森戸　大介Morito Daisuke

研究者情報

基本情報

プロフィール情報

• 氏名

  森戸　大介, Morito Daisuke

所属

• 生化学, 講師

施設

• 旗の台校舎

学位

• 博士(理学), 京都大学, 2008年03月

業績

論文

• もやもや病遺伝子のクローニングから機能解明へ, 森戸　大介, 昭和学士会雑誌, 84(1):56 - 63, 2024年03月, 査読あり, DOI:https://doi.org/10.14930/jshowaunivsoc.84.56
• もやもや病遺伝子の代謝制御機能, 森戸　大介, 生化学, 91(6):815 - 819, 2019年12月, 総説
• The AAA+ ATPase/ubiquitin ligase mysterin stabilizes cytoplasmic lipid droplets., SUGIHARA M;MORITO Daisuke;AINUKI S;HIRANO Y;OGINO K;KITAMURA A;HIRATA H;NAGATA K, J Cell Biol, 218(3):949 - 960, 2019年03月, 原著, 査読あり, DOI:10.1083/jcb.201712120
• ミステリン　もやもや病の責任遺伝子産物, 森戸　大介, 医学のあゆみ, 267(13):1105 - 1110, 2018年12月, 総説
• Nuclear export of ubiquitinated proteins via the UBIN-POST system, Shoshiro Hirayama; Munechika Sugihara; Daisuke Morito; Shun-ichiro Iemura; Tohru Natsume; Shigeo Murata; Kazuhiro Nagata, Proceedings of the National Academy of Sciences of the United States of America, 115(18):E4199 - E4208, 2018年05月
• Nuclear export of ubiquitinated proteins via the UBIN-POST system, Shoshiro Hirayama; Munechika Sugihara; Daisuke Morito; Shun-ichiro Iemura; Tohru Natsume; Shigeo Murata; Kazuhiro Nagata, Proceedings of the National Academy of Sciences of the United States of America, 115(18):E4199 - E4208, 2018年05月
• Nuclear export of ubiquitinated proteins via the UBIN-POST system, Shoshiro Hirayama; Munechika Sugihara; Daisuke Morito; Shun-ichiro Iemura; Tohru Natsume; Shigeo Murata; Kazuhiro Nagata, Proceedings of the National Academy of Sciences of the United States of America, 115(18):E4199 - E4208, 2018年05月
• Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor, Yuri Kotani; Daisuke Morito; Kenshiro Sakata; Shiori Ainuki; Munechika Sugihara; Tomohisa Hatta; Shun-ichiro Iemura; Seiji Takashima; Tohru Natsume; Kazuhiro Nagata, SCIENTIFIC REPORTS, 7, 2017年03月
• Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor, Yuri Kotani; Daisuke Morito; Kenshiro Sakata; Shiori Ainuki; Munechika Sugihara; Tomohisa Hatta; Shun-ichiro Iemura; Seiji Takashima; Tohru Natsume; Kazuhiro Nagata, SCIENTIFIC REPORTS, 7, 2017年03月
• Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor, Yuri Kotani; Daisuke Morito; Kenshiro Sakata; Shiori Ainuki; Munechika Sugihara; Tomohisa Hatta; Shun-ichiro Iemura; Seiji Takashima; Tohru Natsume; Kazuhiro Nagata, SCIENTIFIC REPORTS, 7, 2017年03月
• Neuromuscular regulation in zebrafish by a large AAA plus ATPase/ubiquitin ligase, mysterin/RNF213, Yuri Kotani; Daisuke Morito; Satoru Yamazaki; Kazutoyo Ogino; Koichi Kawakami; Seiji Takashima; Hiromi Hirata; Kazuhiro Nagata, SCIENTIFIC REPORTS, 5, 2015年11月
• Neuromuscular regulation in zebrafish by a large AAA plus ATPase/ubiquitin ligase, mysterin/RNF213, Yuri Kotani; Daisuke Morito; Satoru Yamazaki; Kazutoyo Ogino; Koichi Kawakami; Seiji Takashima; Hiromi Hirata; Kazuhiro Nagata, SCIENTIFIC REPORTS, 5, 2015年11月
• Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments, Janine Kirstein; Daisuke Morito; Taichi Kakihana; Munechika Sugihara; Anita Minnen; Mark S. Hipp; Carmen Nussbaum-Krammer; Prasad Kasturi; F. Ulrich Hartl; Kazuhiro Nagata; Richard I. Morimoto, EMBO JOURNAL, 34(18):2334 - 2349, 2015年09月
• Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments, Janine Kirstein; Daisuke Morito; Taichi Kakihana; Munechika Sugihara; Anita Minnen; Mark S. Hipp; Carmen Nussbaum-Krammer; Prasad Kasturi; F. Ulrich Hartl; Kazuhiro Nagata; Richard I. Morimoto, EMBO JOURNAL, 34(18):2334 - 2349, 2015年09月
• Pathogenic Hijacking of ER-Associated Degradation: Is ERAD Flexible?, Daisuke Morito; Kazuhiro Nagata, MOLECULAR CELL, 59(3):335 - 344, 2015年08月
• Pathogenic Hijacking of ER-Associated Degradation: Is ERAD Flexible?, Daisuke Morito; Kazuhiro Nagata, MOLECULAR CELL, 59(3):335 - 344, 2015年08月
• Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA plus ATPase, which dynamically changes its oligomeric state, Daisuke Morito; Kouki Nishikawa; Jun Hoseki; Akira Kitamura; Yuri Kotani; Kazumi Kiso; Masataka Kinjo; Yoshinori Fujiyoshi; Kazuhiro Nagata, SCIENTIFIC REPORTS, 4, 2014年03月
• Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA plus ATPase, which dynamically changes its oligomeric state, Daisuke Morito; Kouki Nishikawa; Jun Hoseki; Akira Kitamura; Yuri Kotani; Kazumi Kiso; Masataka Kinjo; Yoshinori Fujiyoshi; Kazuhiro Nagata, SCIENTIFIC REPORTS, 4, 2014年03月
• The moyamoya disease susceptibility variant RNF213 R4810K (rs112735431) induces genomic instability by mitotic abnormality, Toshiaki Hitomi; Toshiyuki Habu; Hatasu Kobayashi; Hiroko Okuda; Kouji H. Harada; Kenji Osafune; Daisuke Taura; Masakatsu Sone; Isao Asaka; Tomonaga Ameku; Akira Watanabe; Tomoko Kasahara; Tomomi Sudo; Fumihiko Shiota; Hirokuni Hashikata; Yasushi Takagi; Daisuke Morito; Susumu Miyamoto; Kazuwa Nakao; Akio Koizumi, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 439(4):419 - 426, 2013年10月
• The moyamoya disease susceptibility variant RNF213 R4810K (rs112735431) induces genomic instability by mitotic abnormality, Toshiaki Hitomi; Toshiyuki Habu; Hatasu Kobayashi; Hiroko Okuda; Kouji H. Harada; Kenji Osafune; Daisuke Taura; Masakatsu Sone; Isao Asaka; Tomonaga Ameku; Akira Watanabe; Tomoko Kasahara; Tomomi Sudo; Fumihiko Shiota; Hirokuni Hashikata; Yasushi Takagi; Daisuke Morito; Susumu Miyamoto; Kazuwa Nakao; Akio Koizumi, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 439(4):419 - 426, 2013年10月
• Downregulation of Securin by the variant RNF213 R4810K (rs112735431, G > A) reduces angiogenic activity of induced pluripotent stem cell-derived vascular endothelial cells from moyamoya patients, Toshiaki Hitomi; Toshiyuki Habu; Hatasu Kobayashi; Hiroko Okuda; Kouji H. Harada; Kenji Osafune; Daisuke Taura; Masakatsu Sone; Isao Asaka; Tomonaga Ameku; Akira Watanabe; Tomoko Kasahara; Tomomi Sudo; Fumihiko Shiota; Hirokuni Hashikata; Yasushi Takagi; Daisuke Morito; Susumu Miyamoto; Kazuwa Nakao; Akio Koizumi, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 438(1):13 - 19, 2013年08月
• Downregulation of Securin by the variant RNF213 R4810K (rs112735431, G > A) reduces angiogenic activity of induced pluripotent stem cell-derived vascular endothelial cells from moyamoya patients, Toshiaki Hitomi; Toshiyuki Habu; Hatasu Kobayashi; Hiroko Okuda; Kouji H. Harada; Kenji Osafune; Daisuke Taura; Masakatsu Sone; Isao Asaka; Tomonaga Ameku; Akira Watanabe; Tomoko Kasahara; Tomomi Sudo; Fumihiko Shiota; Hirokuni Hashikata; Yasushi Takagi; Daisuke Morito; Susumu Miyamoto; Kazuwa Nakao; Akio Koizumi, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 438(1):13 - 19, 2013年08月
• ER stress proteins in autoimmune an inflammatory diseases, Daisuke Morito; Kazuhiro Nagata, FRONTIERS IN IMMUNOLOGY, 3(MAR), 2012年
• ER stress proteins in autoimmune an inflammatory diseases, Daisuke Morito; Kazuhiro Nagata, FRONTIERS IN IMMUNOLOGY, 3(MAR), 2012年
• Identification of RNF213 as a Susceptibility Gene for Moyamoya Disease and Its Possible Role in Vascular Development, Wanyang Liu; Daisuke Morito; Seiji Takashima; Yohei Mineharu; Hatasu Kobayashi; Toshiaki Hitomi; Hirokuni Hashikata; Norio Matsuura; Satoru Yamazaki; Atsushi Toyoda; Ken-ichiro Kikuta; Yasushi Takagi; Kouji H. Harada; Asao Fujiyama; Roman Herzig; Boris Krischek; Liping Zou; Jeong Eun Kim; Masafumi Kitakaze; Susumu Miyamoto; Kazuhiro Nagata; Nobuo Hashimoto; Akio Koizumi, PLOS ONE, 6(7), 2011年07月
• Identification of RNF213 as a Susceptibility Gene for Moyamoya Disease and Its Possible Role in Vascular Development, Wanyang Liu; Daisuke Morito; Seiji Takashima; Yohei Mineharu; Hatasu Kobayashi; Toshiaki Hitomi; Hirokuni Hashikata; Norio Matsuura; Satoru Yamazaki; Atsushi Toyoda; Ken-ichiro Kikuta; Yasushi Takagi; Kouji H. Harada; Asao Fujiyama; Roman Herzig; Boris Krischek; Liping Zou; Jeong Eun Kim; Masafumi Kitakaze; Susumu Miyamoto; Kazuhiro Nagata; Nobuo Hashimoto; Akio Koizumi, PLOS ONE, 6(7), 2011年07月
• Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTRΔF508, Morito D; Hirao K; Oda Y; Hosokawa N; Tokunaga F; Cyr D.M; Tanaka K; Iwai K; Nagata K, Molecular Biology of the Cell, 19(4):1328 - 1336, 2008年04月
• Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTRΔF508, Morito D; Hirao K; Oda Y; Hosokawa N; Tokunaga F; Cyr D.M; Tanaka K; Iwai K; Nagata K, Molecular Biology of the Cell, 19(4):1328 - 1336, 2008年04月
• MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination, Shoshiro Hirayama; Yuji Yamazaki; Akira Kitamura; Yukako Oda; Daisuke Morito; Katsuya Okawa; Hiroshi Kimura; Douglas M. Cyr; Hiroshi Kubota; Kazuhiro Nagata, MOLECULAR BIOLOGY OF THE CELL, 19(3):899 - 911, 2008年03月
• MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination, Shoshiro Hirayama; Yuji Yamazaki; Akira Kitamura; Yukako Oda; Daisuke Morito; Katsuya Okawa; Hiroshi Kimura; Douglas M. Cyr; Hiroshi Kubota; Kazuhiro Nagata, MOLECULAR BIOLOGY OF THE CELL, 19(3):899 - 911, 2008年03月
• EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming, K Hirao; Y Natsuka; T Tamura; Wada, I; D Morito; S Natsuka; P Romero; B Sleno; LO Tremblay; A Herscovics; K Nagata; N Hosokawa, JOURNAL OF BIOLOGICAL CHEMISTRY, 281(14):9650 - 9658, 2006年04月
• EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming, K Hirao; Y Natsuka; T Tamura; Wada, I; D Morito; S Natsuka; P Romero; B Sleno; LO Tremblay; A Herscovics; K Nagata; N Hosokawa, JOURNAL OF BIOLOGICAL CHEMISTRY, 281(14):9650 - 9658, 2006年04月
• Dual-site recognition of different extracellular matrix components by anti-angiogenic/neurotrophic serpin, PEDF, N Yasui; T Mori; D Morito; O Matsushita; H Kourai; K Nagata; T Koide, BIOCHEMISTRY, 42(11):3160 - 3167, 2003年03月
• Dual-site recognition of different extracellular matrix components by anti-angiogenic/neurotrophic serpin, PEDF, N Yasui; T Mori; D Morito; O Matsushita; H Kourai; K Nagata; T Koide, BIOCHEMISTRY, 42(11):3160 - 3167, 2003年03月