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Kanamaru Mitsuko

■FacultyFaculty of Arts and Sciences at Fujiyoshida
■PositionProfessor
Last Updated :2025/04/01

Researcher

基本情報

Profile and Settings

  • 氏名

    Kanamaru Mitsuko

Affiliation

  • Faculty of Arts and Sciences at Fujiyoshida, Professor

Location

  • Fujiyoshida Campus

Degree

  • Doctor of Medical Science, Showa University, Oct. 1998

Achievements

Published Papers

  • Exercise evaluation with metabolic and ventilatory responses and blood lactate concentration in mice, Akira Yoshikawa 1, Makito Iizuka 2, Mitsuko Kanamaru 3, Shotaro Kamijo 4, Hirokazu Ohtaki 5, Masahiko Izumizaki 2, Respir Physiol Neurobiol ., :104163, Dec. 2023, Peer-reviewed, DOI:10.1016/j.resp.2023.104163
  • Optogenetic analysis of biological rhythms　ーRespiration and sleep-wake states modulated by brain serotonergic neurons, Mitsuko Kanamaru, Precision　Medicine, 第６巻(第５号):78 - 80, May 2023
  • 【富士吉田教育部における初年次学部連携教育】学部連携をめざしたサイエンス実習　基礎サイエンス実習の変遷, 長谷川　真紀子;稲垣　昌博;金丸　みつ子;佐野　佳弘;久光　隆;宮本　洋一;荒田　悟;萩原　康夫;山本　雅人;本多　英彦;小林　広和;有澤　岳, 昭和学士会雑誌, 82(5):350 - 356, Nov. 2022, Peer-reviewed, DOI:https://doi.org/10.14930/jshowaunivsoc.82.350
  • Optogenetic activation of DRN 5-HT neurons induced active wakefulness, not quiet wakefulness., MORIYA Rica;KANAMARU Mitsuko;OKUMA Naoki;YOSHIKAWA Akira;TANAKA K;HOKARI S;OHSHIMA Y;YAMANAKA A;HONMA Motoyasu;ONIMARU Hiroshi;KIKUCHI T;IZUMIZAKI Masahiko, Brain Res Bull, 177:129 - 142, Dec. 2021, Peer-reviewed
  • Optogenetic analysis of physiological function　－A factor affecting sleep－, 金丸　みつ子, 細胞, 52(10):568 - 569, Sep. 2020
  • Optogenetic Stimulation of 5-HT Neurons in the Median Raphe Nucleus Affects Anxiety and Respiration, OKUMA Naoki;KANAMARU Mitsuko;MORIYA Rika;TANAKA Kenji F.;ARATA Satoru;WATANABE Jun;YOSHIKAWA Akira;IZUMIZAKI Masahiko, Showa Univ J Med Sci, 31(3):263 - 274, Sep. 2019, Peer-reviewed
  • 大縫線核セロトニン神経による疼痛抑制の光遺伝学的解析, 三橋　学;金丸　みつ子;田中　謙二;吉川　輝;稲垣　克記;久光　正;砂川　正隆;泉﨑　雅彦, 昭和学士会雑誌, 79(4):483 - 491, Aug. 2019, Peer-reviewed
  • Neurochemical aspects of obstructive sleep apnea syndrome　－medullary serotonergic system-, 金丸　みつ子, 日本薬理学雑誌, 150(4):177 - 182, Oct. 2017, Peer-reviewed
  • ラット回盲部におけるslow waveの生後発達, 遠藤　利行;飯塚　眞喜人;長谷川　義真;大熊　公樹;岡　厚;矢倉　沙貴;吉川　輝;鬼丸　洋;金丸　みつ子;泉﨑　雅彦, 昭和学士会雑誌, 77(1):88 - 95, Feb. 2017, Peer-reviewed, DOI:10.14930/jshowaunivsoc.77.88
  • Breathing is affected by dopamine D2-like receptors in the basolateral amygdala., SUGITA Toshihisa;KANAMARU Mitsuko;IIZUKA Makito;SATO Kanako;TSUKADA Setsuro;KAWAMURA Mitsuru;HOMMA Ikuo;IZUMIZAKI Masahiko, Respir Physiol Neurobiol, 209:23 - 27, Apr. 2015, Peer-reviewed
  • Early Onset of Ventilatory and Airway Response to Hypercapnia is Mediated by Medullary 5-HT1A Receptors in Infant Rats, MATSUDAIRA Shingo;KANAMARU Mitsuko;IIZUKA Makito;HOMMA Ikuo;IZUMIZAKI Masahiko, Showa Univ J Med Sci, 26(3):211 - 217, Sep. 2014, Peer-reviewed, DOI:10.15369/sujms.26.211
  • Effects of dorsomedial medullary 5-HT2 receptor antagonism on initial ventilatory airway responses to hypercapnic hypoxia in mice., KANAMARU Mitsuko;SUGITA Toshihisa;HOMMA Ikuo, Exp Brain Res, 230(4):547 - 554, Oct. 2013, Peer-reviewed
  • 上気道と下気道の比較と関連　気道の神経生理, 金丸　みつ子;本間　生夫, JOHNS, 29(5):817 - 820, May 2013
  • 【unified airwayからみた鼻副鼻腔病変】 上気道と下気道の比較と関連性 気道の神経生理, 金丸 みつ子; 本間 生夫, JOHNS, 29(5):817 - 820, May 2013
  • 基礎医学からのアプローチ　睡眠障害が呼吸調節機能に与える影響, 金丸　みつ子;本間　生夫, アレルギー･免疫　, 18(2):198 - 207, Jan. 2011
  • 検査・データ編 血液ガス・酸塩基平衡　アシドーシス・アルカローシスの代償反応とは何ですか?, 金丸　みつ子, 呼吸器ケア, (2010冬季増刊):104 - 106, Dec. 2010
  • 【この1冊でらくらくマスター!ベッドサイドで役立つ呼吸アセスメントQ&A101】 検査・データ編 血液ガス・酸塩基平衡 アシドーシス・アルカローシスの代償反応とは何ですか?, 金丸 みつ子, 呼吸器ケア, (2010冬季増刊):104 - 106, Dec. 2010
  • Chemical Control of Airway and Ventilatory Responses Mediated Via Dorsomedial Medullary 5-HT2 Receptors, Mitsuko Kanamaru; Ikuo Homma, NEW FRONTIERS IN RESPIRATORY CONTROL, 669:239 - 242, 2010, Peer-reviewed
  • Dorsomedial medullary 5-HT2 receptors mediate immediate onset of initial hyperventilation, airway dilation, and ventilatory decline during hypoxia in mice, Mitsuko Kanamaru; Ikuo Homma, AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 297(1):R34 - R41, Jul. 2009, Peer-reviewed
  • Serotonin release acts on 5-HT2 receptors in the dorsomedial medulla oblongata to elicit airway dilation in mice, Mitsuko Kanamaru; Ikuo Homma, TRANSMITTERS AND MODULATORS IN HEALTH AND DISEASE, :115 - 123, 2009
  • Time-dependent ventilatory response to poikilocapnic hypoxia during light and dark periods and the role of histamine H1 receptors in mice, Yasuyoshi Ohshima; Michiko Iwase; Masahiko Izumizaki; Mitsuko Kanamaru; Ikuo Homma, JOURNAL OF PHYSIOLOGICAL SCIENCES, 58(2):147 - 150, Apr. 2008, Peer-reviewed
  • Hypoxic ventilatory response during light and dark periods and the involvement of histamine H1 receptor in mice, Yasuyoshi Ohshima; Michiko Iwase; Masahiko Izumizaki; Takashi Ishiguro; Mitsuko Kanamaru; Hideaki Nakayama; Fumitake Gejyo; Ikuo Homma, AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 293(3):R1350 - R1356, Sep. 2007, Peer-reviewed
  • Compensatory airway dilation and additive ventilatory augmentation mediated by dorsomedial medullary 5-hydroxytryptamine 2 receptor activity and hypercapnia, Mitsuko Kanamaru; Ikuo Homma, AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 293(2):R854 - R860, Aug. 2007, Peer-reviewed
  • Lack of histamine type-1 receptors impairs the thermal response of respiration during hypoxia in mice (Mus musculus), Michiko Iwase; Masahiko Izumizaki; Kenichi Miyamoto; Takashi Ishiguro; Mitsuko Kanamaru; Ikuo Homma, COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY, 146(2):242 - 251, Feb. 2007, Peer-reviewed
  • Impaired ventilation and metabolism response to hypoxia in histamine H1 receptor-knockout mice, Takashi Ishiguro; Michiko Iwase; Mitsuko Kanamaru; Masahiko Izumizaki; Yasuyoshi Ohshima; Ikuo Homma, RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, 154(3):331 - 341, Dec. 2006, Peer-reviewed
  • Contribution of histamine type-1 receptor to metabolic and behavioral control of ventilation, Takashi Ishiguro; Michiko Iwase; Mitsuko Kanamaru; Masahiko Izumizaki; Yasuyoshi Hishwa; Ikuo Homma, JOURNAL OF PHYSIOLOGICAL SCIENCES, 56(4):287 - 295, Aug. 2006, Peer-reviewed
  • Control of central histaminergic neurons for respiration during hypercapnia in conscious mice, Michiko Iwase; Masahiko Izumizaki; Kenichi Miyamoto; Mitsuko Kanamaru; Ikuo Homma, BREATHING, FEEDING AND NEUROPROTECTION, :17 - +, 2006
  • Effects of hyperthermia on ventilation and metabolism during hypoxia in conscious mice, M Iwase; M Izumizaki; M Kanamaru; Homma, I, JAPANESE JOURNAL OF PHYSIOLOGY, 54(1):53 - 59, Feb. 2004, Peer-reviewed
  • Central histamine and serotonin in airway motoer control, Mitsuko Kanamaru, Methods Find. Exp. Clin. Pharmacol, 26:43 - 44, 2004
  • 【鼻と肺 上気道と下気道】 呼吸神経生理からみた上気道と下気道の関連, 金丸 みつ子; 本間 生夫, JOHNS, 19(6):773 - 778, Jun. 2003
  • Neuronal histamine release elicited by hyperthermia mediates tracheal dilation and pressor response, M Kanamaru; M Iwase; Homma, I, AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 280(6):R1748 - R1754, Jun. 2001
  • Involvement of central histaminergic neurons in polypnea induced by hyperthermia in rabbits, M Iwase; M Izumizaki; M Kanamaru; Homma, I, NEUROSCIENCE LETTERS, 298(2):119 - 122, Feb. 2001
  • Central histamine and behavioral respiration, Homma, I; M Iwase; M Kanamaru; M Izumizaki, HISTAMINE RESEARCH IN THE NEW MILLENNIUM, 1224:253 - 258, 2001
  • Histamine release in the medulla oblongata influences tracheal tone and blood pressure, M Kanamaru; M Iwase; Homma, I, HISTAMINE RESEARCH IN THE NEW MILLENNIUM, 1224:501 - 502, 2001
  • Central histamine influences respiration in the POA/AH, M Iwase; M Izumizaki; M Kanamaru; Homma, I, HISTAMINE RESEARCH IN THE NEW MILLENNIUM, 1224:497 - 498, 2001
  • Central histaminergic neurons regulate rabbit tracheal tension through the cervical sympathetic nerve, M Iwase; M Kanamaru; A Kanamaru; Homma, I, JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 74(1):23 - 32, Nov. 1998
  • Autoregulation of histamine release in medulla oblongata via H-3-receptors in rabbits, M Kanamaru; M Iwase; Homma, I, NEUROSCIENCE RESEARCH, 31(1):53 - 60, May 1998
  • POSTERIOR HYPOTHALAMIC CONTROL OF RABBIT TRACHEAL TENSION AND INVOLVEMENT OF CENTRAL HISTAMINERGIC NEURONS, M IWASE; M KANAMARU; HOMMA, I, JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 53(1):69 - 76, May 1995
  • CENTRAL MEDIATION OF TRACHEAL PRESSURE THROUGH H(1) AND H(2) RECEPTORS AFTER HISTAMINE ADMINISTRATION TO THE 4TH VENTRICLE OF ANESTHETIZED RABBIT, M KANAMARU; M IWASE; HOMMA, I, NEUROSCIENCE LETTERS, 169(1-2):35 - 38, Mar. 1994
  • SEPARATION OF FREE AMINO-ACIDS BY REVERSED-PHASE ION-PAIR CHROMATOGRAPHY WITH COLUMN SWITCHING AND ISOCRATIC ELUTION, M HIRUKAWA; M MAEDA; A TSUJI; T HANAI, JOURNAL OF CHROMATOGRAPHY, 507:95 - 101, May 1990
  • SELECTIVITY OF AN OCTADECYL-MODIFIED VINYL ALCOHOL COPOLYMER GEL FOR THE RETENTION OF POLAR COMPOUNDS, M HIRUKAWA; T HANAI, JOURNAL OF CHROMATOGRAPHY, 468:191 - 199, May 1989
  • SIMPLE FREE AMINO-ACID SEPARATION BY REVERSED-PHASE ION-PAIR LIQUID-CHROMATOGRAPHY USING COLUMN SWITCHING TECHNIQUE, M HIRUKAWA; T HANAI, JOURNAL OF LIQUID CHROMATOGRAPHY, 11(8):1741 - 1751, 1988
  • RETENTION OF AROMATIC-ACIDS ON AN OCTADECYL-BONDED VINYL ALCOHOL COPOLYMER GEL, Y ARAI; M HIRUKAWA; T HANAI, JOURNAL OF CHROMATOGRAPHY, 400:27 - 32, Jul. 1987

Presentations

  • 漸増運動負荷試験マウスに対する代謝と換気指標をもとにした無酸素性代謝閾値の探索, 吉川　輝;大滝　博和;金丸　みつ子;飯塚　眞喜人;上條　翔太郎;泉﨑　雅彦, 第26回日本基礎理学療法学会学術大会, 24 Oct. 2021, Web開催
  • Optogenetic activation of serotonergic neurons in the dorsal raphe nucleus changes masticatory movements in mice, DANTSUJI Masanori;MOCHIZUKI Ayako;NAKAYAMA Kiyomi;NAKAMURA Shiro;KANAMARU Mitsuko;IZUMIZAKI Masahiko;TANAKA Kenji F;INOUE Tomio, 第44回日本神経科学大会, 28 Jul. 2021, 神戸(Hybrid開催)
  • 呼吸・循環応答とうつ・不安・不眠の程度とモノアミン神経関連遺伝子の連関　第3報, 金丸　みつ子;久光　隆;佐野　佳弘;長谷川　真紀子;松永　雅美;萩原　康夫;小山田　英人;刑部　慶太郎;倉田　知光;稲垣　昌博;大幡　久之;小林　如乃, 第371回昭和大学学士会例会 (アーツ・アンド・サイエンス部会主催), 15 Feb. 2021, 誌上開催
  • 呼吸・循環応答とうつ・不安・不眠の程度とモノアミン神経関連遺伝子の連関　第2報, 金丸　みつ子;長谷川　真紀子;松永　雅美;佐野　佳弘;萩原　康夫;小山田　英人;刑部　慶太郎;倉田　知光;稲垣　昌博;大幡　久之;小林　如乃, 第362回昭和大学学士会例会 (アーツ・アンド・サイエンス部会主催), 18 Feb. 2020, 富士吉田
  • Effects of optogenetic inhibition of 5-HT neurons in the dorsal raphe nucleus on respiratory control, KANAMARU Mitsuko;TSUKADA Mana;YOSHIKAWA Akira;ONIMARU Hiroshi;MOCHIZUKI Ayako;SUNAGAWA Masataka;INOUE Tomio;IZUMIZAKI Masahiko, The 9th Federation of Asian and Oceanian Physiological Societies Congress（FAOPS2019）, 31 Mar. 2019, Kobe
  • 呼吸・循環応答とうつ・不安・不眠の程度とモノアミン神経関連遺伝子の連関, 金丸　みつ子;長谷川　真紀子;松永　雅美;佐野　佳弘;萩原　康夫;小山田　英人;刑部　慶太郎;倉田　知光;稲垣　昌博;大幡　久之, 第353回昭和大学学士会例会 (アーツ・アンド・サイエンス部会主催), 28 Feb. 2019, 東京
  • マウスにおける漸増運動負荷中の呼吸・代謝応答の加齢に伴う変化, 吉川　輝;金丸　みつ子;飯塚　眞喜人;大滝　博和;泉﨑　雅彦, 第23回日本基礎理学療法学会学術大会, 15 Dec. 2018, 京都
  • Optogenetic analysis of nociceptive mechanism mediated by 5-HT neurons in the nucleus raphe magnus, 三橋　学;金丸　みつ子;田中　謙二;吉川　輝;久光　正;砂川　正隆;泉﨑　雅彦, 第95回日本生理学会大会, 29 Mar. 2018, 高松
  • The effect of activating serotonergic neurons in the dorsal raphe nucleus on control of vigilance state., MORIYA Rika;KANAMARU Mitsuko;OKUMA Naoki;TANAKA Kenji;IZUMIZAKI Masahiko;ONIMARU Hiroshi;YOSHIKAWA Akira;HOKARI Satoshi;OSHIMA Yasuyoshi, ERS International Congress 2017, 11 Sep. 2017, Milan
  • Calcium imaging of the locomotor activities in the inspiratory cells in the thoracic spinal cord of the neonatal rat in vitro, 飯塚　眞喜人;岡　厚;長谷川　義真;吉川　輝;金丸　みつ子;鬼丸　洋;泉﨑　雅彦, 第40回日本神経科学大会, 20 Jul. 2017, 千葉
  • Activating dorsal raphe nucleus serotonin neurons affects control of vigilance state switch, 森谷　梨加;金丸　みつ子;大熊　公樹;吉川　輝;田中　謙二;穂苅　諭;大嶋　康義;鬼丸　洋;泉﨑　雅彦, 第94回日本生理学会大会, 30 Mar. 2017, 浜松
  • Relationship between anxiety behavior and respiration control as determined using optogenetics, 大熊　公樹;金丸　みつ子;森谷　梨加;田中　謙二;荒田　悟;渡邊　潤;遠藤　利行;吉川　輝;飯塚　眞喜人;泉﨑　雅彦, 第94回日本生理学会大会, 28 Mar. 2017, 浜松
  • Optogenetic silencing of selected serotonin neurons in the control of CO2-induced arousal, MORIYA Rika;KANAMARU Mitsuko;OOKUMA Naoki;YOSHIKAWA Akira;TANAKA Kenji F.;HOKARI Satoshi;OHSHIMA Yasuyoshi;IZUMIZAKI Masahiko, ERS International Congress 2016, 05 Sep. 2016, London
  • Postnatal development of slow waves in the rat ileocecum, 遠藤　利行;長谷川　義真;大熊　公樹;鬼丸　洋;金丸　みつ子;飯塚　眞喜人;泉﨑　雅彦, 第93回日本生理学会大会, 24 Mar. 2016, 札幌
  • Neurochemical aspects of obstructive sleep apnea syndrome.　 -Medullary serotonergic system-（シンポジウム28　難治性疾患の治療に向けた基礎研究　招待講演）, KANAMARU Mitsuko;IZUMIZAKI Masahiko, 第89回日本薬理学会年会, 11 Mar. 2016, 横浜
  • Post-apneic respiratory responses in patients with obstructive sleep apnea., 金丸　みつ子;横江　琢也;渡部　良雄;相良　博典;泉﨑　雅彦, 第91回日本生理学会大会, 18 Mar. 2014, 鹿児島
  • 睡眠時無呼吸症候群と中枢セロトニン（招待講演）, 金丸　みつ子, 薬物・精神・行動の会, 29 Feb. 2012, 東京
  • 背内側延髄セロトニンの作用から睡眠時無呼吸症候群を考える（招待講演）, 金丸　みつ子, 第38回　Sleep Apneaカンファレンス　, 29 May 2010, 東京

MISC

  • オプトジェネティクスを用いたCO2による覚醒調節機構の解明 (2019年度科学研究費助成事業(基盤研究C)実績報告書), 金丸　みつ子;泉﨑　雅彦;吉川　輝, Jan. 2021
  • オプトジェネティクスを用いたCO2による覚醒調節機構の解明 (科学研究費助成事業(基盤研究C)研究成果報告書), 金丸　みつ子;泉﨑　雅彦;吉川　輝, May 2020
  • オプトジェネティクスを用いたCO2による覚醒調節機構の解明 (2018年度科学研究費助成事業(基盤研究C)実施状況報告書), 金丸　みつ子;泉﨑　雅彦;吉川　輝, Dec. 2019
  • オプトジェネティクスを用いたCO2による覚醒調節機構の解明 (2017年度科学研究費助成事業(基盤研究C)実施状況報告書), 金丸　みつ子;泉﨑　雅彦;吉川　輝, Dec. 2018
  • オプトジェネティクスを用いたCO2による覚醒調節機構の解明 (2016年度科学研究費助成事業(基盤研究C)実施状況報告書), 金丸　みつ子;泉﨑　雅彦;吉川　輝, Jan. 2018

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