船山　英治Funayama Eiji

研究者情報

基本情報

プロフィール情報

• 氏名

  船山　英治, Funayama Eiji

• eメール

  eiji.funayamashowa-u.ac.jp

所属

• 医科薬理学, 助教

施設

• 旗の台校舎

学位

• 博士(薬学), 昭和医科大学, 2025年03月

研究キーワード

• 腫瘍免疫、腸内細菌

所属学協会

• 日本薬理学会
• 日本がん免疫学会

業績

論文

• Inosine shapes PD-1 blockade responses and synergizes with dual PD-1/CTLA-4 immunotherapy to enhance antitumor immunity., Narikawa Yoichiro;Kuramasu Atsuo;Hosonuma Masahiro;Murayama Masakazu;Funayama Eiji;Sasaki Akiko;Baba Yuta;Toyoda Hitoshi;Isobe Junya;Tajima Kohei;Nakashima Rie;Sasaki Aya;Maruyama Yuki;Yamazaki Yoshitaka;Shida Midori;Tsurui Toshiaki;Hirasawa Yuya;Ariizumi Hirotsugu;Ishiguro Tomoyuki;Suzuki Risako;Ohkuma Ryotaro;Kubota Yutaro;Sambe Takehiko;Tsuji Mayumi;Wada Satoshi;Horiike Atsushi;Kobayashi Shinichi;Tsunoda Takuya;Kobayashi Sei;Kobayashi Hitome;Oguchi Tatsunori;Shimane Toshikazu;Kiuchi Yuji;Yoshimura Kiyoshi, Cancer immunology, immunotherapy : CII, 74(9), 2025年08月, 原著, 査読あり, DOI:10.1007/s00262-025-04111-2
• Combination therapy with levofloxacin and the probiotic Clostridium butyricum MIYAIRI 588 enhances immune checkpoint inhibitor efficacy., Tajima Kohei;Hosonuma Masahiro;Funayama Eiji;Isobe Junya;Baba Yuta;Murayama Masakazu;Narikawa Yoichiro;Toyoda Hitoshi;Tsurui Toshiaki;Maruyama Yuki;Sasaki Aya;Amari Yasunobu;Yamazaki Yoshitaka;Nakashima Rie;Shida Midori;Sasaki Akiko;Sambe Takehiko;Wada Satoshi;Tsuji Mayumi;Kiuchi Yuji;Kobayashi Shinichi;Kuramasu Atsuo;Tsunoda Takuya;Mori Masaki;Koyanagi Kazuo;Yoshimura Kiyoshi, International journal of cancer, 157(5), 2025年06月, 原著, 査読あり
• Combination therapy with cetirizine and anti-PD-1 antibody suppresses colitis-induced colon tumor formation in mice., Maruyama Yuki;Hosonuma Masahiro;Toyoda Hitoshi;Funayama Eiji;Sasaki Akiko;Baba Yuta;Tajima Kohei;Nakashima Rie;Sasaki Aya;Shida Midori;Tsurui Toshiaki;Tsuji Mayumi;Tsunoda Takuya;Shimane Toshikazu;Kiuchi Yuji;Yoshimura Kiyoshi;Kuramasu Atsuo, European journal of pharmacology, 999, 2025年05月, 原著, 査読あり
• Veillonella and Streptococcus are associated with aging of the gut microbiota and affect the efficacy of immune checkpoint inhibitors., Hirasawa Yuya;Isobe Junya;Hosonuma Masahiro;Tsurui Toshiaki;Baba Yuta;Funayama Eiji;Tajima Kohei;Murayama Masakazu;Narikawa Yoichiro;Toyoda Hitoshi;Shida Midori;Sasaki Aya;Maruyama Yuuki;Amari Yasunobu;Mura Emiko;Suzuki Risako;Iriguchi Nana;Ishiguro Tomoyuki;Ohkuma Ryotaro;Shimokawa Masahiro;Ariizumi Hirotsugu;Kubota Yutaro;Horiike Atsushi;Sambe Takehiko;Uchida Naoki;Wada Satoshi;Kobayashi Shinichi;Kiuchi Yuji;Kuramasu Atsuo;Yoshimura Kiyoshi;Tsunoda Takuya, Frontiers in immunology, 16, 2025年05月, 原著, 査読あり
• Ki-67 expression in anti-programmed cell death protein-1 antibody-bound CD8+ T cells as a predictor of clinical benefit., Tsurui Toshiaki;Hosonuma Masahiro;Sasaki Aya;Maruyama Yuuki;Amari Yasunobu;Funayama Eiji;Tajima Kohei;Toyoda Hitoshi;Isobe Junya;Yamazaki Yoshitaka;Baba Yuta;Shida Midori;Udaka Yuko;Mura Emiko;Suzuki Risako;Iriguchi Nana;Ishiguro Tomoyuki;Hirasawa Yuya;Ohkuma Ryotaro;Shimokawa Masahiro;Ariizumi Hirotsugu;Kubota Yutaro;Horiike Atsushi;Wada Satoshi;Kuramasu Atsuo;Tsuji Mayumi;Kiuchi Yuji;Tsunoda Takuya;Yoshimura Kiyoshi, Discover oncology, 16(1), 2025年03月, 原著, 査読あり
• Oral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice, 船山　英治, Biomedicine & Pharmacotherapy, 2025年01月, 原著, 査読あり
• Association between the ABCC11 gene polymorphism-determined earwax properties and external auditory canal microbiota in healthy adults., Amari Yasunobu;Hosonuma Masahiro;Mizukami Takuya;Isobe Junya;Azetsu Yuki;Funayama Eiji;Maruyama Yuki;Tsurui Toshiaki;Tajima Kohei;Sasaki Aya;Yamazaki Yoshitaka;Nakano Ryota;Sano Yutaka;Ishida Atsushi;Nakanishi Tatsuya;Mochizuki Seiji;Yoshizawa Yuri;Kumagai Sumito;Yasuhara Sakiko;Ryu Kakei;Oguchi Tatsunori;Kuramasu Atsuo;Yoshimura Kiyoshi;Sambe Takehiko;Kobayashi Sei;Uchida Naoki, Microbiology spectrum, 13(2), 2025年01月, 原著, 査読あり
• Oral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice., Funayama Eiji;Hosonuma Masahiro;Tajima Kohei;Isobe Junya;Baba Yuta;Murayama Masakazu;Narikawa Yoichiro;Toyoda Hitoshi;Tsurui Toshiaki;Maruyama Yuki;Sasaki Aya;Amari Yasunobu;Yamazaki Yoshitaka;Nakashima Rie;Uchiyama Jun;Nakano Ryota;Shida Midori;Sasaki Akiko;Udaka Yuko;Oguchi Tatsunori;Sambe Takehiko;Kobayashi Shinichi;Tsuji Mayumi;Kiuchi Yuji;Kim Yun-Gi;Wada Satoshi;Tsunoda Takuya;Akiyama Masahiro;Nobe Koji;Kuramasu Atsuo;Yoshimura Kiyoshi, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 182, 2024年12月, 原著, 査読あり
• MHC class I polypeptide-related sequence B shedding modulates pancreatic tumor immunity via the activation of NKG2DLow T cells., Toyoda Hitoshi;Kuramasu Atsuo;Hosonuma Masahiro;Murayama Masakazu;Narikawa Yoichiro;Isobe Junya;Baba Yuta;Tajima Kohei;Funayama Eiji;Shida Midori;Maruyama Yuki;Sasaki Aya;Hirasawa Yuya;Tsurui Toshiaki;Ariizumi Hirotsugu;Ishiguro Tomoyuki;Suzuki Risako;Kobayashi Sei;Horiike Atsushi;Hida Noriko;Sambe Takehiko;Nobe Koji;Wada Satoshi;Kobayashi Hitome;Tsuji Mayumi;Kobayashi Shinichi;Tsunoda Takuya;Kudo Yoshifumi;Kiuchi Yuji;Yoshimura Kiyoshi, Scientific reports, 14(1), 2024年10月, 原著, 査読あり
• Isobutyric acid enhances the anti-tumour effect of anti-PD-1 antibody., Murayama Masakazu;Hosonuma Masahiro;Kuramasu Atsuo;Kobayashi Sei;Sasaki Akiko;Baba Yuta;Narikawa Yoichiro;Toyoda Hitoshi;Isobe Junya;Funayama Eiji;Tajima Kohei;Sasaki Aya;Maruyama Yuki;Yamazaki Yoshitaka;Shida Midori;Hamada Kazuyuki;Hirasawa Yuya;Tsurui Toshiaki;Ariizumi Hirotsugu;Ishiguro Tomoyuki;Suzuki Risako;Ohkuma Ryotaro;Kubota Yutaro;Horiike Atsushi;Sambe Takehiko;Tsuji Mayumi;Wada Satoshi;Kobayashi Shinichi;Shimane Toshikazu;Tsunoda Takuya;Kobayashi Hitome;Kiuchi Yuji;Yoshimura Kiyoshi, Scientific reports, 14(1), 2024年05月, 原著, 査読あり
• Nivolumab receptor occupancy on effector regulatory T cells predicts clinical benefit., Hosonuma Masahiro;Hirasawa Yuya;Kuramasu Atsuo;Murayama Masakazu;Narikawa Yoichiro;Toyoda Hitoshi;Baba Yuta;Isobe Junya;Funayama Eiji;Tajima Kohei;Shida Midori;Hamada Kazuyuki;Tsurui Toshiaki;Ariizumi Hirotsugu;Ishiguro Tomoyuki;Suzuki Risako;Ohkuma Ryotaro;Kubota Yutaro;Horiike Atsushi;Sambe Takehiko;Tsuji Mayumi;Wada Satoshi;Kiuchi Yuji;Kobayashi Shinichi;Tsunoda Takuya;Yoshimura Kiyoshi, Cancer science, 115(3), 2024年01月, 原著, 査読あり
• Butyricimonas is a key gut microbiome component for predicting postoperative recurrence of esophageal cancer., Otsuka Koji;Isobe Junya;Asai Yoshiyuki;Nakano Tomohisa;Hattori Kouya;Ariyoshi Tomotake;Yamashita Takeshi;Motegi Kentaro;Saito Akira;Kohmoto Masahiro;Hosonuma Masahiro;Kuramasu Atsuo;Baba Yuta;Murayama Masakazu;Narikawa Yoichiro;Toyoda Hitoshi;Funayama Eiji;Tajima Kohei;Shida Midori;Hirasawa Yuya;Tsurui Toshiaki;Ariizumi Hirotsugu;Ishiguro Tomoyuki;Suzuki Risako;Ohkuma Ryotaro;Kubota Yutaro;Sambe Takehiko;Tsuji Mayumi;Wada Satoshi;Kiuchi Yuji;Kobayashi Shinichi;Horiike Atsushi;Goto Satoru;Murakami Masahiko;Kim Yun-Gi;Tsunoda Takuya;Yoshimura Kiyoshi, Cancer immunology, immunotherapy : CII, 73(2), 2024年01月, 原著, 査読あり
• Turicibacter and Acidaminococcus predict immune-related adverse events and efficacy of immune checkpoint inhibitor., Hamada Kazuyuki;Isobe Junya;Hattori Kouya;Hosonuma Masahiro;Baba Yuta;Murayama Masakazu;Narikawa Yoichiro;Toyoda Hitoshi;Funayama Eiji;Tajima Kohei;Shida Midori;Hirasawa Yuya;Tsurui Toshiaki;Ariizumi Hirotsugu;Ishiguro Tomoyuki;Suzuki Risako;Ohkuma Ryotaro;Kubota Yutaro;Sambe Takehiko;Tsuji Mayumi;Wada Satoshi;Kiuchi Yuji;Kobayashi Shinichi;Kuramasu Atsuo;Horiike Atsushi;Kim Yun-Gi;Tsunoda Takuya;Yoshimura Kiyoshi, Frontiers in immunology, 14, 2023年05月, 原著, 査読あり