矢野　文子Yano Fumiko

研究者情報

基本情報

プロフィール情報

• 氏名

  矢野　文子, Yano Fumiko

• eメール

  fumikoyanodent.showa-u.ac.jp

ID各種

• 研究者番号

  80529040

所属

• 統括研究推進センター, 講師

施設

• 旗の台校舎

学位

• 博士(医学), 東京大学, 2006年03月

業績

論文

• 関節のバイオロジー ～関節の恒常性を司る，滑膜と軟骨の連関制御機構の解明～, 矢野　文子, 昭和学士会雑誌, 84(1):70 - 74, 2024年03月, 査読あり, DOI:https://doi.org/10.14930/jshowaunivsoc.84.70
• Runx2 and Runx3 differentially regulate articular chondrocytes during surgically induced osteoarthritis development., Nagata Kosei;Hojo Hironori;Chang Song Ho;Okada Hiroyuki;Yano Fumiko;Chijimatsu Ryota;Omata Yasunori;Mori Daisuke;Makii Yuma;Kawata Manabu;Kaneko Taizo;Iwanaga Yasuhide;Nakamoto Hideki;Maenohara Yuji;Tachibana Naohiro;Ishikura Hisatoshi;Higuchi Junya;Taniguchi Yuki;Ohba Shinsuke;Chung Ung-Il;Tanaka Sakae;Saito Taku, Nature communications, 13(1):6187 - 6187, 2022年10月, 原著, 査読あり, DOI:10.1038/s41467-022-33744-5
• RSPO2 defines a distinct undifferentiated progenitor in the tendon/ligament and suppresses ectopic ossification., Naohiro Tachibana; Ryota Chijimatsu; Hiroyuki Okada; Takeshi Oichi; Yuki Taniguchi; Yuji Maenohara; Junya Miyahara; Hisatoshi Ishikura; Yasuhide Iwanaga; Yusuke Arino; Kosei Nagata; Hideki Nakamoto; So Kato; Toru Doi; Yoshitaka Matsubayashi; Yasushi Oshima; Asuka Terashima; Yasunori Omata; Fumiko Yano; Shingo Maeda; Shiro Ikegawa; Masahide Seki; Yutaka Suzuki; Sakae Tanaka; Taku Saito, Science advances, 8(33):eabn2138, 2022年08月
• Effects of conditioned medium obtained from human adipose-derived stem cells on skin inflammation., Fumiko Yano; Taiga Takeda; Takafumi Kurokawa; Toshiya Tsubaki; Ryota Chijimatsu; Keita Inoue; Shinsaku Tsuji; Sakae Tanaka; Taku Saito, Regenerative therapy, 20:72 - 77, 2022年04月, 原著, DOI:10.1016/j.reth.2022.03.009
• Regulation of osteoarthritis development by ADAM17/Tace in articular cartilage., Taizo Kaneko; Keisuke Horiuchi; Ryota Chijimatsu; Daisuke Mori; Kosei Nagata; Yasunori Omata; Fumiko Yano; Hiroshi Inui; Toru Moro; Sakae Tanaka; Taku Saito, Journal of bone and mineral metabolism, 40(2):196 - 207, 2022年03月
• Involvement of Transient Receptor Potential Vanilloid Channel 2 in the Induction of Lubricin and Suppression of Ectopic Endochondral Ossification in Mouse Articular Cartilage., Hideki Nakamoto; Yuki Katanosaka; Ryota Chijimatsu; Daisuke Mori; Fengjun Xuan; Fumiko Yano; Yasunori Omata; Yuji Maenohara; Yasutaka Murahashi; Kohei Kawaguchi; Ryota Yamagami; Hiroshi Inui; Shuji Taketomi; Yuki Taniguchi; Motoi Kanagawa; Keiji Naruse; Sakae Tanaka; Taku Saito, Arthritis & rheumatology (Hoboken, N.J.), 73(8):1441 - 1450, 2021年08月
• Ear Cartilage Reconstruction Combining Induced Pluripotent Stem Cell-Derived Cartilage and Three-Dimensional Shape-Memory Scaffold., Sakura Uto; Atsuhiko Hikita; Tomoaki Sakamoto; Daisuke Mori; Fumiko Yano; Shinsuke Ohba; Taku Saito; Tsuyoshi Takato; Kazuto Hoshi, Tissue engineering. Part A, 27(9-10):604 - 617, 2021年05月
• Lubricin Contributes to Homeostasis of Articular Cartilage by Modulating Differentiation of Superficial Zone Cells., Yuji Maenohara; Ryota Chijimatsu; Naohiro Tachibana; Kosuke Uehara; Fengjun Xuan; Daisuke Mori; Yasutaka Murahashi; Hideki Nakamoto; Takeshi Oichi; Song Ho Chang; Takumi Matsumoto; Yasunori Omata; Fumiko Yano; Sakae Tanaka; Taku Saito, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 36(4):792 - 802, 2021年04月
• Evidence that TD-198946 enhances the chondrogenic potential of human synovium-derived stem cells through the NOTCH3 signaling pathway., Masato Kobayashi; Ryota Chijimatsu; David A Hart; Shuichi Hamamoto; George Jacob; Fumiko Yano; Taku Saito; Kazunori Shimomura; Wataru Ando; Ung-Il Chung; Sakae Tanaka; Hideki Yoshikawa; Norimasa Nakamura, Journal of tissue engineering and regenerative medicine, 15(2):103 - 115, 2021年02月
• The small compound, TD-198946, protects against intervertebral degeneration by enhancing glycosaminoglycan synthesis in nucleus pulposus cells., Junichi Kushioka; Takashi Kaito; Ryota Chijimatsu; Rintaro Okada; Hiroyuki Ishiguro; Zeynep Bal; Joe Kodama; Fumiko Yano; Taku Saito; Ung-Il Chung; Sakae Tanaka; Hideki Yoshikawa, Scientific reports, 10(1):14190 - 14190, 2020年08月
• Associations of clinical outcomes and MRI findings in intra-articular administration of autologous adipose-derived stem cells for knee osteoarthritis., Junya Higuchi; Ryota Yamagami; Takumi Matsumoto; Tomohiro Terao; Keita Inoue; Shinsaku Tsuji; Yuji Maenohara; Tokio Matsuzaki; Ryota Chijimatsu; Yasunori Omata; Fumiko Yano; Sakae Tanaka; Taku Saito, Regenerative therapy, 14:332 - 340, 2020年06月
• Enhancement of chondrogenic differentiation supplemented by a novel small compound for chondrocyte-based tissue engineering., Shuichi Hamamoto; Ryota Chijimatsu; Kazunori Shimomura; Masato Kobayashi; George Jacob; Fumiko Yano; Taku Saito; Ung-Il Chung; Sakae Tanaka; Norimasa Nakamura, Journal of experimental orthopaedics, 7(1):10 - 10, 2020年03月
• Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling., Keita Okada; Daisuke Mori; Yuma Makii; Hideki Nakamoto; Yasutaka Murahashi; Fumiko Yano; Song Ho Chang; Yuki Taniguchi; Hiroshi Kobayashi; Hiroaki Semba; Norihiko Takeda; Wen Piao; Kenjiro Hanaoka; Tetsuo Nagano; Sakae Tanaka; Taku Saito, Scientific reports, 10(1):5425 - 5425, 2020年03月
• Primary culture of mouse adipose and fibrous synovial fibroblasts under normoxic and hypoxic conditions., Hikaru Sugimoto; Yasutaka Murahashi; Ryota Chijimatsu; Satoshi Miwa; Fumiko Yano; Sakae Tanaka; Taku Saito, Biomedical research (Tokyo, Japan), 41(1):43 - 51, 2020年
• Oral administration of EP4-selective agonist KAG-308 suppresses mouse knee osteoarthritis development through reduction of chondrocyte hypertrophy and TNF secretion., Yasutaka Murahashi; Fumiko Yano; Ryota Chijimatsu; Hideki Nakamoto; Yuji Maenohara; Masahiro Amakawa; Yoshihide Miyake; Hiroyuki Yamanaka; Kousuke Iba; Toshihiko Yamashita; Sakae Tanaka; Taku Saito, Scientific reports, 9(1):20329 - 20329, 2019年12月
• Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone., Fengjun Xuan; Fumiko Yano; Daisuke Mori; Ryota Chijimatsu; Yuji Maenohara; Hideki Nakamoto; Yoshifumi Mori; Yuma Makii; Takeshi Oichi; Makoto Mark Taketo; Hironori Hojo; Shinsuke Ohba; Ung-Il Chung; Sakae Tanaka; Taku Saito, Arthritis research & therapy, 21(1):247 - 247, 2019年11月
• Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds., Manabu Kawata; Daisuke Mori; Kosuke Kanke; Hironori Hojo; Shinsuke Ohba; Ung-Il Chung; Fumiko Yano; Hideki Masaki; Makoto Otsu; Hiromitsu Nakauchi; Sakae Tanaka; Taku Saito, Stem cell reports, 13(3):530 - 544, 2019年09月
• Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway., Oichi Takeshi;Taniguchi Yuki;Soma Kazuhito;Oshima Yasushi;Yano Fumiko;Mori Yoshifumi;Chijimatsu Ryota;Kim-Kaneyama Joo-Ri;Tanaka Sakae;Saito Taku, Cellular and molecular life sciences : CMLS, 76(23), 2019年06月
• Runx1 contributes to articular cartilage maintenance by enhancement of cartilage matrix production and suppression of hypertrophic differentiation., Fumiko Yano; Shinsuke Ohba; Yasutaka Murahashi; Sakae Tanaka; Taku Saito; Ung-Il Chung, Scientific reports, 9(1):7666 - 7666, 2019年05月
• Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway., Chang Song Ho;Mori Daisuke;Kobayashi Hiroshi;Mori Yoshifumi;Nakamoto Hideki;Okada Keita;Taniguchi Yuki;Sugita Shurei;Yano Fumiko;Chung Ung-Il;Kim-Kaneyama Joo-Ri;Yanagita Motoko;Economides Aris;Canalis Ernesto;Chen Di;Tanaka Sakae;Saito Taku, Nature communications, 10(1), 2019年03月
• Effect of the small compound TD-198946 on glycosaminoglycan synthesis and transforming growth factor β3-associated chondrogenesis of human synovium-derived stem cells in vitro., Ryota Chijimatsu; Fumiko Yano; Taku Saito; Masato Kobayashi; Shuichi Hamamoto; Takashi Kaito; Junichi Kushioka; David A Hart; Ung-Il Chung; Sakae Tanaka; Hideki Yoshikawa; Norimasa Nakamura, Journal of tissue engineering and regenerative medicine, 13(3):446 - 458, 2019年03月
• Multi-layered PLLA-nanosheets loaded with FGF-2 induce robust bone regeneration with controlled release in critical-sized mouse femoral defects., Yasutaka Murahashi; Fumiko Yano; Hideki Nakamoto; Yuji Maenohara; Kousuke Iba; Toshihiko Yamashita; Sakae Tanaka; Kazuhiko Ishihara; Yosuke Okamura; Toru Moro; Taku Saito, Acta biomaterialia, 85:172 - 179, 2019年02月
• Multi-layered PLLA-nanosheets loaded with FGF-2 induce robust bone regeneration with controlled release in critical-sized mouse femoral defects., Murahashi Yasutaka;Yano Fumiko;Nakamoto Hideki;Maenohara Yuji;Iba Kousuke;Yamashita Toshihiko;Tanaka Sakae;Ishihara Kazuhiko;Okamura Yosuke;Moro Toru;Saito Taku, Acta biomaterialia, 85, 2018年12月
• Intra-articular administration of IκBα kinase inhibitor suppresses mouse knee osteoarthritis via downregulation of the NF-κB/HIF-2α axis., Yasutaka Murahashi; Fumiko Yano; Hiroshi Kobayashi; Yuma Makii; Kousuke Iba; Toshihiko Yamashita; Sakae Tanaka; Taku Saito, Scientific reports, 8(1):16475 - 16475, 2018年11月
• A Mouse Intervertebral Disc Degeneration Model by Surgically Induced Instability., Takeshi Oichi; Yuki Taniguchi; Kazuhito Soma; Song Ho Chang; Fumiko Yano; Sakae Tanaka; Taku Saito, Spine, 43(10):E557-E564, 2018年05月
• Bone regeneration by human dental pulp stem cells using a helioxanthin derivative and cell-sheet technology., Yasuyuki Fujii; Yoko Kawase-Koga; Hironori Hojo; Fumiko Yano; Marika Sato; Ung-Il Chung; Shinsuke Ohba; Daichi Chikazu, Stem cell research & therapy, 9(1):24 - 24, 2018年02月
• Alteration of gait parameters in a mouse model of surgically induced knee osteoarthritis., Makii Yuma;Asaka Meiko;Setogawa Susumu;Fujiki Soichiro;Hosaka Yoko;Yano Fumiko;Oka Hiroyuki;Tanaka Sakae;Fukui Naoshi;Yanagihara Dai;Saito Taku, Journal of orthopaedic surgery (Hong Kong), 26(2), 2018年
• Sandwich-type PLLA-nanosheets loaded with BMP-2 induce bone regeneration in critical-sized mouse calvarial defects., Kuo-Chin Huang; Fumiko Yano; Yasutaka Murahashi; Shuta Takano; Yoshiaki Kitaura; Song Ho Chang; Kazuhito Soma; Steve W N Ueng; Sakae Tanaka; Kazuhiko Ishihara; Yosuke Okamura; Toru Moro; Taku Saito, Acta biomaterialia, 59:12 - 20, 2017年09月
• Regulation of Chondrocyte Survival in Mouse Articular Cartilage by p63., Yuki Taniguchi; Manabu Kawata; Song Ho Chang; Daisuke Mori; Keita Okada; Hiroshi Kobayashi; Shurei Sugita; Yoko Hosaka; Hiroshi Inui; Shuji Taketomi; Fumiko Yano; Toshiyuki Ikeda; Haruhiko Akiyama; Alea A Mills; Ung-Il Chung; Sakae Tanaka; Hiroshi Kawaguchi; Taku Saito, Arthritis & rheumatology (Hoboken, N.J.), 69(3):598 - 609, 2017年03月
• Different regulation of limb development by p63 transcript variants., Manabu Kawata; Yuki Taniguchi; Daisuke Mori; Fumiko Yano; Shinsuke Ohba; Ung-Il Chung; Tomomi Shimogori; Alea A Mills; Sakae Tanaka; Taku Saito, PloS one, 12(3):e0174122, 2017年
• Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes., Kobayashi Hiroshi;Chang Song Ho;Mori Daisuke;Itoh Shozo;Hirata Makoto;Hosaka Yoko;Taniguchi Yuki;Okada Keita;Mori Yoshifumi;Yano Fumiko;Chung Ung-Il;Akiyama Haruhiko;Kawaguchi Hiroshi;Tanaka Sakae;Saito Taku, Nature communications, 7:13336 - 13336, 2016年11月
• Comparison of mouse and human ankles and establishment of mouse ankle osteoarthritis models by surgically-induced instability, Song Ho Chang, T Yasui, S Taketomi, T Matsumoto, J R Kim-Kaneyama, T Omiya, Y Hosaka, H Inui, Y Omata, R Yamagami , D Mori , F Yano, U Chung , S Tanaka, T Saito, Osteoarthritis Cartilage, 2016年04月, 原著, 査読あり
• Runx1 and Runx3 Are Downstream Effectors of Nanog in Promoting Osteogenic Differentiation of the Mouse Mesenchymal Cell Line C3H10T1/2., Tadahito Saito; Shinsuke Ohba; Fumiko Yano; Ichiro Seto; Yoshiyuki Yonehara; Tsuyoshi Takato; Toru Ogasawara, Cellular reprogramming, 17(3):227 - 34, 2015年06月
• Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 2., Shurei Sugita; Yoko Hosaka; Keita Okada; Daisuke Mori; Fumiko Yano; Hiroshi Kobayashi; Yuki Taniguchi; Yoshifumi Mori; Tomotake Okuma; Song Ho Chang; Manabu Kawata; Shuji Taketomi; Hirotaka Chikuda; Haruhiko Akiyama; Ryoichiro Kageyama; Ung-Il Chung; Sakae Tanaka; Hiroshi Kawaguchi; Shinsuke Ohba; Taku Saito, Proceedings of the National Academy of Sciences of the United States of America, 112(10):3080 - 5, 2015年03月
• Regulation of mouse chondrocyte differentiation by CCAAT/enhancer-binding proteins., Tomotake Okuma; Makoto Hirata; Fumiko Yano; Daisuke Mori; Hiroshi Kawaguchi; Ung-il Chung; Sakae Tanaka; Taku Saito, Biomedical research (Tokyo, Japan), 36(1):21 - 9, 2015年
• Hyaline cartilage formation and tumorigenesis of implanted tissues derived from human induced pluripotent stem cells., Taku Saito; Fumiko Yano; Daisuke Mori; Manabu Kawata; Kazuto Hoshi; Tsuyoshi Takato; Hideki Masaki; Makoto Otsu; Koji Eto; Hiromitsu Nakauchi; Ung-il Chung; Sakae Tanaka, Biomedical research (Tokyo, Japan), 36(3):179 - 86, 2015年
• Disease-modifying effects of TD-198946 on progressed osteoarthritis in a mouse model., Fumiko Yano; Shinsuke Ohba; Yoko Hosaka; Taku Saito; Ung-Il Chung, Annals of the rheumatic diseases, 73(11):2062 - 4, 2014年11月
• Identification of SCAN domain zinc-finger gene ZNF449 as a novel factor of chondrogenesis., Keita Okada; Atsushi Fukai; Daisuke Mori; Yoko Hosaka; Fumiko Yano; Ung-il Chung; Hiroshi Kawaguchi; Sakae Tanaka; Toshiyuki Ikeda; Taku Saito, PloS one, 9(12):e115169, 2014年
• Cell-sheet technology combined with a thienoindazole derivative small compound TD-198946 for cartilage regeneration., Fumiko Yano; Hironori Hojo; Shinsuke Ohba; Taku Saito; Muneki Honnami; Manabu Mochizuki; Tsuyoshi Takato; Hiroshi Kawaguchi; Ung-il Chung, Biomaterials, 34(22):5581 - 7, 2013年07月
• A novel disease-modifying osteoarthritis drug candidate targeting Runx1., Fumiko Yano; Hironori Hojo; Shinsuke Ohba; Atsushi Fukai; Yoko Hosaka; Toshiyuki Ikeda; Taku Saito; Makoto Hirata; Hirotaka Chikuda; Tsuyoshi Takato; Hiroshi Kawaguchi; Ung-il Chung, Annals of the rheumatic diseases, 72(5):748 - 53, 2013年05月
• Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium., Hironori Hojo; Shinsuke Ohba; Kiyomi Taniguchi; Masataka Shirai; Fumiko Yano; Taku Saito; Toshiyuki Ikeda; Keiji Nakajima; Yuske Komiyama; Naomi Nakagata; Kentaro Suzuki; Yuji Mishina; Masahisa Yamada; Tomohiro Konno; Tsuyoshi Takato; Hiroshi Kawaguchi; Hideki Kambara; Ung-Il Chung, The Journal of biological chemistry, 288(14):9924 - 9932, 2013年04月
• β-catenin regulates parathyroid hormone/parathyroid hormone-related protein receptor signals and chondrocyte hypertrophy through binding to the intracellular C-terminal region of the receptor., Fumiko Yano; Taku Saito; Naoshi Ogata; Toshiko Yamazawa; Masamitsu Iino; Ung-il Chung; Hiroshi Kawaguchi, Arthritis and rheumatism, 65(2):429 - 35, 2013年02月
• Nanog promotes osteogenic differentiation of the mouse mesenchymal cell line C3H10T1/2 by modulating bone morphogenetic protein (BMP) signaling., Toru Ogasawara; Shinsuke Ohba; Fumiko Yano; Hiroshi Kawaguchi; Ung-Il Chung; Tadahito Saito; Yoshiyuki Yonehara; Takashi Nakatsuka; Yoshiyuki Mori; Tsuyoshi Takato; Kazuto Hoshi, Journal of cellular physiology, 228(1):163 - 71, 2013年01月
• Tenomodulin expression in the periodontal ligament enhances cellular adhesion., Yuske Komiyama; Shinsuke Ohba; Nobuyuki Shimohata; Keiji Nakajima; Hironori Hojo; Fumiko Yano; Tsuyoshi Takato; Denitsa Docheva; Chisa Shukunami; Yuji Hiraki; Ung-Il Chung, PloS one, 8(4):e60203, 2013年
• Generation of Col2a1-EGFP iPS cells for monitoring chondrogenic differentiation., Taku Saito; Fumiko Yano; Daisuke Mori; Shinsuke Ohba; Hironori Hojo; Makoto Otsu; Koji Eto; Hiromitsu Nakauchi; Sakae Tanaka; Ung-il Chung; Hiroshi Kawaguchi, PloS one, 8(9):e74137, 2013年
• Gli1 protein participates in Hedgehog-mediated specification of osteoblast lineage during endochondral ossification., Hironori Hojo; Shinsuke Ohba; Fumiko Yano; Taku Saito; Toshiyuki Ikeda; Keiji Nakajima; Yuske Komiyama; Naomi Nakagata; Kentaro Suzuki; Tsuyoshi Takato; Hiroshi Kawaguchi; Ung-Il Chung, The Journal of biological chemistry, 287(21):17860 - 17869, 2012年05月
• Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage., Ryosuke Echigo; Nobuyuki Shimohata; Kensuke Karatsu; Fumiko Yano; Yuko Kayasuga-Kariya; Ayano Fujisawa; Takayo Ohto; Yoshihiro Kita; Motonao Nakamura; Shigeki Suzuki; Manabu Mochizuki; Takao Shimizu; Ung-Il Chung; Nobuo Sasaki, Journal of translational medicine, 10:80 - 80, 2012年04月
• C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes., Makoto Hirata; Fumitaka Kugimiya; Atsushi Fukai; Taku Saito; Fumiko Yano; Toshiyuki Ikeda; Akihiko Mabuchi; Bishwa Raj Sapkota; Toru Akune; Nao Nishida; Noriko Yoshimura; Takumi Nakagawa; Katsushi Tokunaga; Kozo Nakamura; Ung-il Chung; Hiroshi Kawaguchi, Human molecular genetics, 21(5):1111 - 23, 2012年03月
• [Novel small compound in combination with cell-sheet technology for articular cartilage regeneration]., Fumiko Yano; Hironori Hojo; Ung il Chung, Clinical calcium, 21(6):871 - 7, 2011年06月
• Identification of oxytetracycline as a chondrogenic compound using a cell-based screening system., Hironori Hojo; Fumiko Yano; Shinsuke Ohba; Kazuyo Igawa; Keiji Nakajima; Yuske Komiyama; Akinori Kan; Toshiyuki Ikeda; Takayuki Yonezawa; Je-Tae Woo; Tsuyoshi Takato; Kozo Nakamura; Hiroshi Kawaguchi; Ung-il Chung, Journal of bone and mineral metabolism, 28(6):627 - 33, 2010年11月
• Trehalose inhibits oral dryness by protecting the cell membrane, Mori Y, Yano F, Shimohata N, Suzuki S, Chung UI, Takato T., Int J Oral Maxillofac Surg, 2010年09月, 原著, 査読あり
• Coordination of chondrogenesis and osteogenesis by hypertrophic chondrocytes in endochondral bone development., Hironori Hojo; Shinsuke Ohba; Fumiko Yano; Ung-il Chung, Journal of bone and mineral metabolism, 28(5):489 - 502, 2010年09月
• Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development., Taku Saito; Atsushi Fukai; Akihiko Mabuchi; Toshiyuki Ikeda; Fumiko Yano; Shinsuke Ohba; Nao Nishida; Toru Akune; Noriko Yoshimura; Takumi Nakagawa; Kozo Nakamura; Katsushi Tokunaga; Ung-Il Chung; Hiroshi Kawaguchi, Nature medicine, 16(6):678 - 86, 2010年06月
• Enhancement of bone formation ex vivo and in vivo by a helioxanthin-derivative., Keiji Nakajima; Yusuke Komiyama; Hironori Hojo; Shinsuke Ohba; Fumiko Yano; Naoko Nishikawa; Sigeo Ihara; Hiroyuki Aburatani; Tsuyoshi Takato; Ung-Il Chung, Biochemical and biophysical research communications, 395(4):502 - 8, 2010年05月
• Runx1 and Runx2 cooperate during sternal morphogenesis., Ayako Kimura; Hiroyuki Inose; Fumiko Yano; Koji Fujita; Toshiyuki Ikeda; Shingo Sato; Makiko Iwasaki; Tetsuya Jinno; Keisuke Ae; Seiji Fukumoto; Yasuhiro Takeuchi; Hiroshi Itoh; Takeshi Imamura; Hiroshi Kawaguchi; Ung-il Chung; James F Martin; Sachiko Iseki; Ken-ichi Shinomiya; Shu Takeda, Development (Cambridge, England), 137(7):1159 - 67, 2010年04月
• Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions., Atsushi Fukai; Naohiro Kawamura; Taku Saito; Yasushi Oshima; Toshiyuki Ikeda; Fumitaka Kugimiya; Akiro Higashikawa; Fumiko Yano; Naoshi Ogata; Kozo Nakamura; Ung-Il Chung; Hiroshi Kawaguchi, Arthritis and rheumatism, 62(3):826 - 36, 2010年03月
• Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER: identification of sorting nexin 19 as a novel factor., Akinori Kan; Toshiyuki Ikeda; Taku Saito; Fumiko Yano; Atushi Fukai; Hironori Hojo; Toru Ogasawara; Naoshi Ogata; Kozo Nakamura; Ung-Il Chung; Hiroshi Kawaguchi, Arthritis and rheumatism, 60(11):3314 - 23, 2009年11月
• Transcriptional induction of SOX9 by NF-kappaB family member RelA in chondrogenic cells, M Ushita , T Saito, T Ikeda, F Yano, A Higashikawa, N Ogata, U Chung, K Nakamura, H Kawaguchi, Osteoarthritis Cartilage, 2009年08月, 原著, 査読あり
• Temporal and spatial changes in element distribution in bone and cartilage., Kenichi Yamamoto; Kazuyo Igawa; Hiroshi Ueno; Fumiko Yano; Ung-Il Chung; Isao Koshima, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 14(2):198 - 203, 2009年03月
• Tissue engineering of bone and cartilage, Ohba S, Yano F, Chung U, IBMS Bone Key, 2009年, 原著, 査読あり
• C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57., Makoto Hirata; Fumitaka Kugimiya; Atsushi Fukai; Shinsuke Ohba; Naohiro Kawamura; Toru Ogasawara; Yosuke Kawasaki; Taku Saito; Fumiko Yano; Toshiyuki Ikeda; Kozo Nakamura; Ung-Il Chung; Hiroshi Kawaguchi, PloS one, 4(2):e4543, 2009年
• Development of high-throughput screening system for osteogenic drugs using a cell-based sensor., Hironori Hojo; Kazuyo Igawa; Shinsuke Ohba; Fumiko Yano; Keiji Nakajima; Yuske Komiyama; Toshiyuki Ikeda; Alexander C Lichtler; Je-Tae Woo; Takayuki Yonezawa; Tsuyoshi Takato; Ung-il Chung, Biochemical and biophysical research communications, 376(2):375 - 9, 2008年11月
• Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes., Yosuke Kawasaki; Fumitaka Kugimiya; Hirotaka Chikuda; Satoru Kamekura; Toshiyuki Ikeda; Naohiro Kawamura; Taku Saito; Yusuke Shinoda; Akiro Higashikawa; Fumiko Yano; Toru Ogasawara; Naoshi Ogata; Kazuto Hoshi; Franz Hofmann; James R Woodgett; Kozo Nakamura; Ung-il Chung; Hiroshi Kawaguchi, The Journal of clinical investigation, 118(7):2506 - 15, 2008年07月
• Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcription activator., Hiroyuki Tamiya; Toshiyuki Ikeda; Jae-Hwan Jeong; Taku Saito; Fumiko Yano; Youn-Kwan Jung; Shinsuke Ohba; Hiroshi Kawaguchi; Ung-Il Chung; Je-Yong Choi, Gene, 416(1-2):53 - 60, 2008年06月
• Identification of a potent combination of osteogenic genes for bone regeneration using embryonic stem (ES) cell-based sensor., Shinsuke Ohba; Toshiyuki Ikeda; Fumitaka Kugimiya; Fumiko Yano; Alexander C Lichtler; Kozo Nakamura; Tsuyoshi Takato; Hiroshi Kawaguchi; Ung-il Chung, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 21(8):1777 - 87, 2007年06月
• Identification and characterization of the human SOX6 promoter., Toshiyuki Ikeda; Taku Saito; Masahiro Ushita; Fumiko Yano; Akinori Kan; Keiji Itaka; Toru Moro; Kozo Nakamura; Hiroshi Kawaguchi; Ung-Il Chung, Biochemical and biophysical research communications, 357(2):383 - 90, 2007年06月
• Mechanism of osteogenic induction by FK506 via BMP/Smad pathways., Fumitaka Kugimiya; Fumiko Yano; Shinsuke Ohba; Kazuyo Igawa; Kozo Nakamura; Hiroshi Kawaguchi; Ung-il Chung, Biochemical and biophysical research communications, 338(2):872 - 9, 2005年12月
• Involvement of endogenous bone morphogenetic protein (BMP) 2 and BMP6 in bone formation., Fumitaka Kugimiya; Hiroshi Kawaguchi; Satoru Kamekura; Hirotaka Chikuda; Shinsuke Ohba; Fumiko Yano; Naoshi Ogata; Takenobu Katagiri; Yoshifumi Harada; Yoshiaki Azuma; Kozo Nakamura; Ung-il Chung, The Journal of biological chemistry, 280(42):35704 - 12, 2005年10月
• The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner., Fumiko Yano; Fumitaka Kugimiya; Shinsuke Ohba; Toshiyuki Ikeda; Hirotaka Chikuda; Toru Ogasawara; Naoshi Ogata; Tsuyoshi Takato; Kozo Nakamura; Hiroshi Kawaguchi; Ung-Il Chung, Biochemical and biophysical research communications, 333(4):1300 - 8, 2005年08月