Sugawara Hirohito

Researcher

基本情報

Profile and Settings

• 氏名

  Sugawara Hirohito

Affiliation

• Nephrology, Assistant Professor

Location

• Northern Yokohama Hospital

Achievements

Published Papers

• Renin-angiotensin system inhibitor use and cardio-renal outcomes in non-proteinuric chronic kidney disease: a post-hoc analysis of the Frontier of Renal Outcome Modification-Japan study, Hirohito Sugawara, Kiryu Yoshida, Chie Saito, Yoshinori Saito, Masanori Kato, Akihiko Kato, Ichiei Narita, Shoichi Maruyama, Jun Wada, Takashi Wada, Masahiro Yamamoto, Hidetoshi Ito, Kunihiro Yamagata, Hiroaki Ogata, Hypertension Research, Apr. 2026, Peer-reviewed
• IgG4-Related Pericarditis Diagnosed by Accumulated Pericardial Effusion., Sugawara Hirohito;Takahashi Tomokazu;Kimura Yukishige;Matsui Azumi;Matsumoto Tamaki;Nishisato Kimio;Nishimura Mitsuhiro, Case reports in cardiology, 2023, Nov. 2023, Peer-reviewed, DOI:https://doi.org/10.1155/2023/9223342
• Seasonal variation of serum 25-hydroxyvitamin D level in hemodialysis patients in the northernmost island of Japan., Gocho Y, Tanaka M, Sugawara H, Furuhashi M, Moniwa N, Yamashita T, Takizawa H, Mukai H, Ohno K, Maeda T, Osanami A, Ohnishi H, Komatsu H, Mori K, Miura T., Clin Exp Nephrol., 25(12):1360 - 1366, Dec. 2021, Peer-reviewed
• Involvement of necroptosis in contrast-induced nephropathy in a rat CKD model., Shibata S, Moniwa N, Kuno A, Kimura A, Ohwada W, Sugawara H, Gocho Y, Tanaka M, Yano T, Furuhashi M, Tanno M, Miki T, Miura T., Clin Exp Nephrol., 25(7):708 - 717, Jul. 2021, Peer-reviewed
• Activation of the angiotensin II receptor promotes autophagy in renal proximal tubular cells and affords protection from ischemia/reperfusion injury., Sugawara H, Moniwa N, Kuno A, Ohwada W, Osanami A, Shibata S, Kimura Y, Abe K, Gocho Y, Tanno M, Miura T., J Pharmacol Sci., 145(2):187 - 197, Feb. 2021, Peer-reviewed
• Cardiac Light Chain Deposition Disease Mimicking Immunoglobulin Light Chain Amyloidosis: Two Branches of the Same Tree., Osanami A, Yano T, Takemura G, Ikeda H, Inyaku M, Toda Y, Kamiyama N, Sugawara H, Gocho Y, Fujito T, Nagano N, Takahashi S, Muranaka A, Tanaka M, Moniwa N, Murase K, Takada K, Kuroda H, Ogawa Y, Miura T., Circ Cardiovasc Imaging., 13(e010478), 2020, Peer-reviewed
• Distinct intra-mitochondrial localizations of pro-survival kinases and regulation of their functions by DUSP5 and PHLPP-1., Ohwada W, Tanno M, Yano T, Ong SB, Abe K, Sato T, Kuno A, Miki T, Sugawara H, Igaki Y, Miura T., Biochim Biophys Acta Mol Basis Dis., 1866(165851), 2020, Peer-reviewed
• mTORC1 inhibition attenuates necroptosis through RIP1 inhibition-mediated TFEB activation., Abe K, Yano T, Tanno M, Miki T, Kuno A, Sato T, Kouzu H, Nakata K, Ohwada W, Kimura Y, Sugawara H, Shibata S, Igaki Y, Ino S, Miura T., Biochim Biophys Acta Mol Basis Dis., 1865(165552), 2019, Peer-reviewed
• Canagliflozin, a sodium-glucose cotransporter 2 inhibitor, normalizes renal susceptibility to type 1 cardiorenal syndrome through reduction of renal oxidative stress in diabetic rats., Kimura Y, Kuno A, Tanno M, Sato T, Ohno K, Shibata S, Nakata K, Sugawara H, Abe K, Igaki Y, Yano T, Miki T, Miura T., J Diabetes Investig., 10:933 - 946, 2019, Peer-reviewed
• Anti-glomerular basement membrane disease accompanied by systemic lupus erythematosus presenting central nervous system involvement., Sugawara H, Takizawa H, Shimamura Y, Moniwa N, Hasegawa K, Ogawa Y., CEN case Rep., 6:1 - 4, 2017, Peer-reviewed
• Impact of the Number of Anti-Thrombosis Agents in Hemodialysis Patients: BOREAS-HD2 Study., Tanaka M, Moniwa N, Ohnishi H, Yamashita T, Koyama M, Gocho Y, Nishizawa K, Kimura Y, Sugawara H, Murakami S, Okazaki Y, Furuhashi M, Yoshida H, Miura T., Kidney Blood Press Res., 42:553 - 564, 2017, Peer-reviewed
• Suppressed autophagic response underlies augmentation of renal ischemia/reperfusion injury by type 2 diabetes., Muratsubaki S, Kuno A, Tanno M, Miki T, Yano T, Sugawara H, Shibata S, Abe K, Ishikawa S, Ohno K, Kimura Y, Tatekoshi Y, Nakata K, Ohwada W, Mizuno M, Miura T., Sci Rep., 7(5311), 2017, Peer-reviewed
• Acute interstitial nephritis with membranous nephropathy in bucillamine-treated rheumatoid arthritis., Takamatsu N, Takizawa H, Sugawara H, Ogawa Y., CEN case Rep., 5:103 - 107, 2016, Peer-reviewed
• A Case of Acute Renal Failure Associated with IgG4-Related Disease Presenting Both Tubulointerstitial Nephritis and Retroperitoneal Fibrosis., Sugawara H, Takizawa H, Moniwa N, Takamatsu N, Ohashi Y, Ogawa Y., Open Journal of Nephrology., 6:86 - 92, 2016, Peer-reviewed
• 心サルコイドーシスの診断と治療における18F-FDG-PET/心筋SPECTイメージングの有用性と問題点, 菅原　浩仁、西沢　慶太郎、中田　潤、須永　大介、多田　智洋、佐藤　健司、福眞　隆行、北　宏之、梶　智人、中田　智明、老松　寛, 函館五稜郭病院医誌, 22:9 - 12, Sep. 2014, Peer-reviewed
• Case report; Selective serotonin reuptake inhibitor induced QT prolongation and ventricular fibrillation in acute myocardial infarction., Tada T, Nakata J, Sugawara H, Nishizawa K, Sunaga D, Sato K, Fukuma T, Kita H, NakataT, Oimatsu H., Nihon Naika Gakkai Zasshi., 103:738 - 740, 2014, Peer-reviewed
• Aortic valve aneurysm responsible for acute congestive heart failure and histological findings: A case report., Sugawara H, Matsumoto T, Hotta H, Yoshida D, Kato N, Ohata J, Ishii K, Yuda S, Murakami T, Shibata S, Ishizu A, Ooiwa H, Fujise Y, Nakata T., Journal of Cardiology Cases., 10:100 - 103, 2014, Peer-reviewed
• Clinical efficacies of myocardial fatty acid metabolism imaging in risk stratification and prognosis assessment in patients with chronic kidney disease or undergoing hemodialysis treatment: basic concept and clinical implications., Nakata T, Hashimoto A, Obara F, Yoshihara M, Sugawara H, Nishizawa K., Nihon Toseki Igakkai Zasshi., 47:57 - 65, 2014, Peer-reviewed
• Cardiac metaiodobenzylguanidine imaging and heart failure., Nakata T, Hashimoto A, Sugawara H., Curr Heart Fall Rep., 10:359 - 364, 2013, Peer-reviewed

Presentations

• Clinical characteristic of undiagnosed coronary artery disease (uCAD) in individuals initiating hemodialysis (HD)., Hirohito Sugawara, Kiryu Yoshida, Yoshinori Saito, Masanori Kato, Masahiro Yamamoto, Hidetoshi Ito, Suguru Shimazu, Masahiko Ochiai, Hiroaki Ogata, Kidney Week ASN 2024, Oct. 2024, San Diego, USA
• 高齢者心不全患者における肝硬変の検討　心肝連関における腎臓の役割, 菅原　浩仁、木村　幸滋、西村　光弘、吉田　輝龍、齋藤　佳範、加藤　雅典、山本　真寛、伊藤　英利、緒方　浩顕, 第67回日本腎臓学会学術総会, Jun. 2024
• Liver elasticity in elderly heart failure patient -the role of kidney in cardio-hepatic interaction-., Hirohito Sugawara, Yukishige Kimura, Mitsuhiro Nishimura, Kiryu Yoshida, Masahiro Yamamoto, Hidetoshi Ito, Hiroaki Ogata, APCN 2024, Jun. 2024, Seoul, Korea
• Liver elasticity in heart failure patient: the role of kidney in cardio-hepatic interaction., Hirohito Sugawara, Kimura Yukishige, Azumi Matsui, Tamaki Matsumoto, Kimio Nishisato, Mitsuhiro Nishimura, Kidney Week ASN 2023, Nov. 2023, Philadelphia, USA
• Liver elasticity in elderly heart failure patient., Hirohito Sugawara, Kimura Yukishige, Azumi Matsui, Tamaki Matsumoto, Kimio Nishisato, Mitsuhiro Nishimura, AHA 2023, Nov. 2023, Philadelphia, USA
• フェブキソスタットはインスリン抵抗性動物モデルの虚血再灌流障害を軽減する, 菅原　浩仁、茂庭　仁人、三浦　哲嗣, 第63回日本腎臓学会学術総会, Aug. 2020
• Protection afforded by angiotensin II receptor activation against acute kidney injury is associated with upregulation of tubular autophagy., Hirohito Sugawara, Norihito Moniwa, Masaya Tanno, Takayuki Miki, Atsushi Kuno, Toshiyuki Yano, Tatsuya Sato, Hidemichi Kouzu, Satoru Shibata, Tetsuji Miura, ISN WCN 2020, Mar. 2020, Abu Dhabi, UAE
• AKIに対するアンジオテンシンII前投与による腎保護効果はAT1およびMas受容体減少の軽減とautophagy活性化を伴う, 菅原　浩仁、茂庭　仁人、柴田　智、矢野　俊之、久野　篤史、丹野　雅也、三木　隆幸、三浦　哲嗣, 第62回日本腎臓学会学術総会, Jun. 2019
• Protection afforded by angiotensin II receptor activation against acute kidney injury is associated with upregulation of tubular autophagy., Hirohito Sugawara, Norihito Moniwa, Toshiyuki Yano, Atsushi Kuno, Masaya Tanno, Takayuki Miki, Satoru Shibata, Yukishige Kimura, Tetsuji Miura, 2nd Asia Pacific AKI CRRT Congress, Aug. 2018, Taipei, Taiwan
• アンジオテンシンIIの短期投与は尿細管autophagyを活性化し、急性腎障害を軽減する, 菅原　浩仁、茂庭　仁人、柴田　智、木村　幸滋、山下　智久、矢野　俊之、久野　篤史、丹野　雅也、三木　隆幸、三浦　哲嗣, 第61回日本腎臓学会学術総会, Jun. 2018
• Role of Enhanced Necroptosis Induced by Impaired Autophagy in Aggravation of Renal Ischemia-reperfusion Injury in Type 2 Diabetes., Hirohito Sugawara, Shingo Muratsubaki, Atsushi Kuno, Koki Abe, Tatsuya Sato, Toshiyuki Yano, Masaya Tanno, Takayuki Miki, Tetsuji Miura, 第82回日本循環器学会学術集会, Mar. 2018
• Activation of the angiotensin II receptor alleviates renal ischemia-reperfusion injury with upregulation of tubular autophagy before ischemia., Hirohito Sugawara, Norihito Moniwa, Toshiyuki Yano, Atsushi Kuno, Masaya Tanno, Takayuki Miki, Satoru Shibata, Yukishige Kimura, Tomohisa Yamashita, Tetsuji Miura, ISN Frontiers Meeting 2018, Feb. 2018, Tokyo
• 2型糖尿病による腎虚血再灌流障害の増悪におけるautophagy障害の役割, 菅原　浩仁、茂庭　仁人、柴田　智、山下　智久、村椿　真悟、久野　篤史、矢野　俊之、丹野　雅也、三木　隆幸、三浦　哲嗣, 第60回日本腎臓学会学術総会, May 2017
• 透析患者の貧血管理における季節性変動, 菅原　浩仁、滝沢　英毅、大谷　美穂、茂庭　仁人、長谷川　浩一、大野　紘平、山下　智久、富樫　信彦、西谷　彰紘, 第61回日本透析医学会通常総会, Jun. 2016
• 多彩な症状を呈したSLEと抗GBM抗体病の合併例, 菅原　浩仁、滝沢　英毅、茂庭　仁人、長谷川　浩一、嶋村　昌之介、田中　繁道、小川弥生、浦　信行, 第45回日本腎臓学会東部学術大会, Oct. 2015
• 心サルコイドーシス診断と治療におけるFDG-PET/心筋血流SPECTイメージングの有用性と問題点, 菅原　浩仁、西沢　慶太郎、須永　大介、多田　智洋、佐藤　健司、福眞　隆行、北　宏之、中田　智明、梶　智人、金子　尚史, 第66回道南医学会大会, Nov. 2013
• 急激な血糖悪化を契機に偶然発見され、多腺性内分泌腫瘍症1型が疑われた１例, 菅原　浩仁、小笠原　惇、伊藤　孝仁、田中　希尚、古橋　眞人、下重　晋也、丹野　雅也、三浦　哲嗣, 第46回日本糖尿病学会北海道地方会, 11 Nov. 2012
• 特発性右房拡張症の１例, 菅原　浩仁、小笠原　惇、村中　敦子、川向　美奈、望月　敦史、伊藤　孝仁、丹野　雅也、下重　晋也、湯田　聡、橋本　暁佳、土橋　和文、三浦　哲嗣, 日本超音波医学会第42回北海道地方会学術集会, 27 Oct. 2012
• ACTH産生褐色細胞腫の１例, 菅原　浩仁、須永　大介、藤戸　健史、小山　雅之、丹野　雅也、橋本　暁佳、土橋　和文、三浦　哲嗣, 第12回日本内分泌学会北海道支部学術集会, 06 Oct. 2012
• 血胸を来した両側肺動静脈瘻の１例, 菅原　浩仁、小栗　満、河井　康孝, 第102回日本呼吸器学会北海道支部会学術集会, 17 Sep. 2011
• 大動脈弁瘤により大動脈弁閉鎖不全症と大動脈弁狭窄を呈した１例, 菅原　浩仁、松本　倫明、堀田　寛之、吉田　大輔、加藤　伸郎、大畑　純一、石井　勝久、大岩　均、湯田　聡, 第106回日本循環器学会北海道地方会, 10 Sep. 2011

Books etc

• 高血圧学(上), 高血圧領域における循環生理活性物質研究の進歩と展望(RAA系を除く) カリクレイン・ キニン系(解説/特集), 茂庭　仁人、菅原　浩仁, 日本臨床, 2020