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Kuwata Hiroshi

■FacultyHealth Chemistry
■PositionAssociate Professor
Last Updated :2026/08/12

Researcher

基本情報

Profile and Settings

  • 氏名

    Kuwata Hiroshi

Identifiers

  • ORCID ID

    0000-0002-2158-6907

Affiliation

  • Health Chemistry, Associate Professor

Location

  • Hatanodai Campus

Degree

  • Doctor of Pharmaceutical Science, Showa University, Dec. 2001

Achievements

Published Papers

  • Prostacyclin synthase deficiency exacerbates systemic inflammatory responses in lipopolysaccharide-induced septic shock in mice., Tsubasa Ochiai; Toshiya Honsawa; Keishi Yamaguchi; Yuka Sasaki; Chieko Yokoyama; Hiroshi Kuwata; Shuntaro Hara, Inflammation research : official journal of the European Histamine Research Society ... [et al.], Jun. 2024, Peer-reviewed
  • Deficiency of long-chain acyl-CoA synthetase 4 leads to lipopolysaccharide-induced mortality in a mouse model of septic shock., Kuwata Hiroshi;Nakatani Eriko;Tomitsuka Yuki;Ochiai Tsubasa;Sasaki Yuka;Yoda Emiko;Hara Shuntaro, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 37(12), Dec. 2023, Peer-reviewed, DOI:10.1096/fj.202301314R
  • Gene deletion of long-chain acyl-CoA synthetase 4 attenuates xenobiotic chemical-induced lung injury via the suppression of lipid peroxidation., Yuki Tomitsuka; Hiroki Imaeda; Haruka Ito; Isaki Asou; Masayuki Ohbayashi; Fumihiro Ishikawa; Hiroshi Kuwata; Shuntaro Hara, Redox biology, 66:102850 - 102850, Aug. 2023, Peer-reviewed, DOI:10.1016/j.redox.2023.102850
  • Role of ACSL4 in the chemical-induced cell death in human proximal tubule epithelial HK-2 cells, Hiroshi Kuwata; Yuki Tomitsuka; Emiko Yoda; Shuntaro Hara, Bioscience Reports, 42(2):BSR20212433, Feb. 2022, Peer-reviewed
  • Absence of prostacyclin greatly relieves cyclophosphamide-induced cystitis and bladder pain in mice., Tsubasa Ochiai; Yuka Sasaki; Chieko Yokoyama; Hiroshi Kuwata; Shuntaro Hara, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 35(10):e21952, Oct. 2021, Peer-reviewed
  • Substrate Specificity of Human Long-Chain Acyl-CoA Synthetase ACSL6 Variants, Kurotaki Anri;Kuwata Hiroshi;Hara Shuntaro, Biological and Pharmaceutical Bulletin, 44(10):1571 - 1575, Oct. 2021, Peer-reviewed, DOI:10.1248/bpb.b21-00551
  • Gene deletion of microsomal prostaglandin E synthase-1 suppresses chemically induced skin carcinogenesis., SASAKI Yuka;KUWATA Hiroshi;AIDA Eri;OCHIAI Tsubasa;KAMEI Daisuke;NAKATANI Yoshihito;HARA Shuntaro, Anticancer Res, 41(3):1307 - 1314, Mar. 2021, Peer-reviewed
  • Involvement of prostacyclin synthase in high-fat-diet-induced obesity., SASAKI Yuka;KUWATA Hiroshi;AKATSU Moe;YAMAKAWA Yuri;OCHIAI Tsubasa;YODA Emiko;NAKATANI Yoshihito;YOKOYAMA Chieko;HARA Shuntaro, Prostaglandins Other Lipid Mediat, 153:106523, Dec. 2020, Peer-reviewed
  • Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure., Yamada Naoya;Karasawa Tadayoshi;Kimura Hiroaki;Watanabe Sachiko;Komada Takanori;Kamata Ryo;Sampilvanjil Ariunaa;Ito Junya;Nakagawa Kiyotaka;Kuwata Hiroshi;Hara Shuntaro;Mizuta Koichi;Sakuma Yasunaru;Sata Naohiro;Takahashi Masafumi, Cell death & disease, 11(2):144 - 144, Feb. 2020, Peer-reviewed
  • Gene Deletion of Calcium-Independent Phospholipase A2γ (iPLA2γ) Suppresses Adipogenic Differentiation of Mouse Embryonic Fibroblasts., Emiko Yoda; Keiko Hachisu; Hiroshi Kuwata; Yoshihito Nakatani; Shuntaro Hara, Biological & pharmaceutical bulletin, 43(9):1375 - 1381, 2020, Peer-reviewed, DOI:10.1248/bpb.b20-00321
  • Role of acyl-CoA synthetase ACSL4 in arachidonic acid metabolism., Hiroshi Kuwata; Shuntaro Hara, Prostaglandins & other lipid mediators, 144:106363 - 106363, Oct. 2019, Peer-reviewed
  • Long-chain acyl-CoA synthetase 4 participates in the formation of highly unsaturated fatty acid-containing phospholipids in murine macrophages., Kuwata Hiroshi;Nakatani Eriko;Shimbara-Matsubayashi Satoko;Ishikawa Fumihiro;Shibanuma Motoko;Sasaki Yuka;Yoda Emiko;Nakatani Yoshihito;Hara Shuntaro, Biochimica et biophysica acta. Molecular and cell biology of lipids, 1864(11):1606 - 1618, Jul. 2019, Peer-reviewed
  • Analysis on the Substrate Specificity of Recombinant Human Acyl-CoA Synthetase ACSL4 Variants., Satoko Shimbara-Matsubayashi; Hiroshi Kuwata; Nobutada Tanaka; Masaru Kato; Shuntaro Hara, Biological & pharmaceutical bulletin, 42(5):850 - 855, 2019, Peer-reviewed, DOI:10.1248/bpb.b19-00085
  • Calcium-independent phospholipase A2γ (iPLA2γ) and its roles in cellular functions and diseases., Hara Shuntaro;Yoda Emiko;Sasaki Yuka;Nakatani Yoshihito;Kuwata Hiroshi, Biochimica et biophysica acta. Molecular and cell biology of lipids, 1864(6), Nov. 2018, Peer-reviewed
  • The group VIA calcium-independent phospholipase A2 and NFATc4 pathway mediates IL-1β-induced expression of chemokines CCL2 and CXCL10 in rat fibroblasts., KUWATA Hiroshi;YUZURIHARA Chihiro;KINOSHITA Natsumi;TAKI Yuki;IKEGAMI Yuki;WASHIO Sana;HIRAKAWA Yushi;YODA Emiko;AIUCHI Toshihiro;ITABE Hiroyuki;NAKATANI Yoshihito;HARA Shuntaro, FEBS J, 285(11):2056 - 2070, Jun. 2018, Peer-reviewed
  • Inhibition of amyloid fibril formation and cytotoxicity by caffeic acid-conjugated amyloid-β C-terminal peptides, ARAI Takuya;OHNO Akiko;MORI Kazunori;KUWATA Hiroshi;MIZUNO Mirei;IMAI Kohei;HARA Shuntaro;SHIBANUMA Motoko;KURIHARA Masaaki;MIYATA Naoki;NAKAGAWA Hidehiko;FUKUHARA Kiyoshi, Bioorg Med Chem Lett, 26(22):5468 - 5471, Nov. 2016, Peer-reviewed
  • Design, synthesis, and evaluation of Trolox-conjugated amyloid-β C-terminal peptides for therapeutic intervention in an in vitro model of Alzheimer's disease., Takuya Arai; Akiko Ohno; Mori Kazunori; Taeko Kakizawa; Hiroshi Kuwata; Toshihiko Ozawa; Motoko Shibanuma; Shuntaro Hara; Seiichi Ishida; Masaaki Kurihara; Naoki Miyata; Hidehiko Nakagawa; Kiyoshi Fukuhara, Bioorganic & medicinal chemistry, 24(18):4138 - 4143, Sep. 2016, Peer-reviewed
  • Genetic-deletion of Cyclooxygenase-2 Downstream Prostacyclin Synthase Suppresses Inflammatory Reactions but Facilitates Carcinogenesis, unlike Deletion of Microsomal Prostaglandin E Synthase-1, SASAKI Yuka;KAMIYAMA Shuhei;KAMIYAMA Azusa;MATSUMOTO Konomi;AKATSU Moe;NAKATANI Yoshihito;KUWATA Hiroshi;ISHIKAWA Yukio;ISHII Toshiharu;YOKOYAMA Chieko;HARA Shuntaro, Sci Rep, 5(17376):1 - 11, Nov. 2015, Peer-reviewed
  • Inhibition of long-chain acyl-CoA synthetase 4 facilitates production of 5, 11-dihydroxyeicosatetraenoic acid via the cyclooxygenase-2 pathway., Hiroshi Kuwata; Shuntaro Hara, Biochemical and biophysical research communications, 465(3):528 - 33, Sep. 2015, Peer-reviewed
  • Group VIB calcium-independent phospholipase A2 (iPLA2γ) regulates platelet activation, hemostasis and thrombosis in mice., YODA Emiko; RAI Kohmi; OGAWA Mai; TAKAKURA Yuki; KUWATA Hiroshi; SUZUKI Hidenori; NAKATANI Yoshihito; MURAKAMI Makoto; HARA Shuntaro, PLOS ONE, 9(10):e109409, Oct. 2014, Peer-reviewed
  • 10. Group VIB calcium-independent phospholipase A2 (iPLA2γ) regulates platelet activation, hemostasis and thrombosis in mice., YODA Emiko;RAI Kohmi;OGAWA Mai;TAKAKURA Yuki;KUWATA Hiroshi; SUZUKI Hidenori; NAKATANI Yoshihito; MURAKAMI Makoto;HARA Shuntaro, PLOS ONE, e0109409, Oct. 2014, Peer-reviewed, DOI:10.1371/journal.pone.0109409
  • Group VIB calcium-independent phospholipase A2 (iPLA2γ) regulates platelet activation, hemostasis and thrombosis in mice., YODA Emiko;RAI Kohmi;OGAWA Mai;TAKAKURA Yuki;KUWATA Hiroshi; SUZUKI Hidenori; NAKATANI Yoshihito; MURAKAMI Makoto;HARA Shuntaro, PLOS ONE, e0109409, Oct. 2014, Peer-reviewed, DOI:10.1371/journal.pone.0109409
  • Time course-changes in phosphatidylcholine profile during oxidative modification of low-density lipoprotein., SASABE Naoko;KEYAMURA Yuka;OBAMA Takashi;INOUE Nozomi;MASUKO Yukihiro;IGARASHI Yu;AIUCHI Toshihiro;KATO Rina;YAMAGUCHI Tomohiro;KUWATA Hiroshi;IWAMOTO Sanju;MIYAZAKI Akira;HARA Shuntaro;YOSHIKAWA Tomohiro;ITABE Hiroyuki, Lipids Health Dis, 13:48, Mar. 2014, Peer-reviewed, DOI:https://doi.org/10.1186/1476-511X-13-48
  • Role of long-chain acyl-coenzyme A synthetases in the regulation of arachidonic acid metabolism in interleukin 1β-stimulated rat fibroblasts., Hiroshi Kuwata; Makiko Yoshimura; Yuka Sasaki; Emiko Yoda; Yoshihito Nakatani; Ichiro Kudo; Shuntaro Hara, Biochimica et biophysica acta, 1841(1):44 - 53, Jan. 2014, Peer-reviewed
  • Group VIB calcium-independent phospholipase A2 (iPLA2γ) regulates platelet activation, hemostasis and thrombosis in mice., Emiko Yoda; Kohmi Rai; Mai Ogawa; Yuki Takakura; Hiroshi Kuwata; Hidenori Suzuki; Yoshihito Nakatani; Makoto Murakami; Shuntaro Hara, PloS one, 9(10):e109409, 2014, Peer-reviewed
  • Mitochondrial dysfunction and reduced prostaglandin synthesis in skeletal muscle of Group VIB Ca2+-independent phospholipase A2gamma-deficient mice., Emiko Yoda; Keiko Hachisu; Yoshitaka Taketomi; Kotomi Yoshida; Masanori Nakamura; Kazutaka Ikeda; Ryo Taguchi; Yoshihito Nakatani; Hiroshi Kuwata; Makoto Murakami; Ichiro Kudo; Shuntaro Hara, Journal of lipid research, 51(10):3003 - 15, Oct. 2010, Peer-reviewed
  • Differential contributions of protein kinase C isoforms in the regulation of group IIA secreted phospholipase A2 expression in cytokine-stimulated rat fibroblasts., Mizuki Sugita; Hiroshi Kuwata; Ichiro Kudo; Shuntaro Hara, Biochimica et biophysica acta, 1801(1):70 - 6, Jan. 2010, Peer-reviewed
  • Regulation of sPLA(2)-IIA expression in cytokine-stimulated rat fibroblasts, Hiroshi Kuwata; Ichiro Kudo, NEW FRONTIERS IN LIFESTYLE-RELATED DISEASES, :143 - 146, 2008
  • A novel role of group VIB calcium-independent phospholipase A2 (iPLA2gamma) in the inducible expression of group IIA secretory PLA2 in rat fibroblastic cells., Hiroshi Kuwata; Chikako Fujimoto; Emiko Yoda; Satoko Shimbara; Yoshihito Nakatani; Shuntaro Hara; Makoto Murakami; Ichiro Kudo, The Journal of biological chemistry, 282(28):20124 - 32, Jul. 2007, Peer-reviewed
  • Search of factors that intermediate cytokine-induced group IIA phospholipase A2 expression through the cytosolic phospholipase A2- and 12/15-lipoxygenase-dependent pathway., Hiroshi Kuwata; Takuya Nonaka; Makoto Murakami; Ichiro Kudo, The Journal of biological chemistry, 280(27):25830 - 9, Jul. 2005, Peer-reviewed
  • Group VIB Ca2+-independent phospholipase A2gamma promotes cellular membrane hydrolysis and prostaglandin production in a manner distinct from other intracellular phospholipases A2., Makoto Murakami; Seiko Masuda; Kaori Ueda-Semmyo; Emiko Yoda; Hiroshi Kuwata; Yasukazu Takanezawa; Junken Aoki; Hiroyuki Arai; Hideki Sumimoto; Yukio Ishikawa; Toshiharu Ishii; Yoshihito Nakatani; Ichiro Kudo, The Journal of biological chemistry, 280(14):14028 - 41, Apr. 2005, Peer-reviewed
  • Group IIA secretory phospholipase A2 is a unique 12/15-lipoxygenase-regulated gene in cytokine-stimulated rat fibroblastic 3Y1 cells., Hiroshi Kuwata; Shinji Yamamoto; Akiko Takekura; Makoto Murakami; Ichiro Kudo, Biochimica et biophysica acta, 1686(1-2):15 - 23, Nov. 2004, Peer-reviewed
  • Induction of distinct sets of secretory phospholipase A(2) in rodents during inflammation., Katsuhiko Hamaguchi; Hiroshi Kuwata; Kumiko Yoshihara; Seiko Masuda; Satoko Shimbara; Sachiko Oh-ishi; Makoto Murakami; Ichiro Kudo, Biochimica et biophysica acta, 1635(1):37 - 47, Nov. 2003, Peer-reviewed
  • Type IIA secretory PLA2-mediated delayed PGE2 biosynthesis is regulated by the products of the cytosolic PLA2., Hiroshi Kuwata; Shinji Yamamoto; Yoshihito Nakatani; Makoto Murakami; Ichiro Kudo, Advances in experimental medicine and biology, 507:9 - 13, 2002
  • Studies on a mechanism by which cytosolic phospholipase A2 regulates the expression and function of type IIA secretory phospholipase A2, H. Kuwata; S. Yamamoto; Y. Miyazaki; S. Shimbara; Y. Nakatani; H. Suzuki; N. Ueda; S. Yamamoto; M. Murakami; I. Kudo, Journal of Immunology, 165(7):4024 - 4031, Oct. 2000, Peer-reviewed
  • Interferon-γ and interleukin 4 inhibit interleukin 1β-induced delayed prostagilandin E2 generation through suppression of cyclooxugenase-2 expression in human fibroblasts, Yoshinori Hayashi; Makoto Kobayashi; Hiroshi Kuwata; Gen-Ichi Atsumi; Katsutoshi Deguchi; Xiu Feng Wei; Ichiro Kudo; Kohji Hasegawa, Cytokine, 12(6):603 - 612, 2000, Peer-reviewed
  • Functional association of type IIA secretory phospholipase A, with the glycosylphosphatidylinositol-anchored heparan sulfate proteoglycan in the cyclooxygenase-2-mediated delayed prostanoid-biosynthetic pathway, M Murakami; T Kambe; S Shimbara; S Yamamoto; H Kuwata; Kudo, I, JOURNAL OF BIOLOGICAL CHEMISTRY, 274(42):29927 - 29936, Oct. 1999, Peer-reviewed
  • Characterization of heparin low-affinity phospholipase A(1) present in brain and testicular tissue, S Uchiyama; Y Miyazaki; Y Amakasu; H Kuwata; Y Nakatani; G Atsumi; M Murakami; Kudo, I, JOURNAL OF BIOCHEMISTRY, 125(6):1001 - 1010, Jun. 1999, Peer-reviewed
  • Role of type IIA secretory phospholipase A(2) in arachidonic acid metabolism, H Kuwata; H Sawada; M Murakami; Kudo, I, EICOSANOIDS AND OTHER BIOACTIVE LIPIDS IN CANCER, IMFLAMMATION AND RADIATION INJURY, 4, 469:183 - 188, 1999
  • The functions of five distinct mammalian phospholipase A(2)S in regulating arachidonic acid release - Type IIA and type V secretory phospholipase A(2)S are functionally redundant and act in concert with cytosolic phospholipase A(2), M Murakami; S Shimbara; T Kambe; H Kuwata; MV Winstead; JA Tischfield; Kudo, I, JOURNAL OF BIOLOGICAL CHEMISTRY, 273(23):14411 - 14423, Jun. 1998, Peer-reviewed
  • Cytosolic phospholipase A(2) is required for cytokine-induced expression of type IIA secretory phospholipase A(2) that mediates optimal cyclooxygenase-2-dependent delayed prostaglandin E-2 generation in rat 3Y1 fibroblasts, H Kuwata; Y Nakatani; M Murakami; Kudo, I, JOURNAL OF BIOLOGICAL CHEMISTRY, 273(3):1733 - 1740, Jan. 1998, Peer-reviewed
  • Cancer cells isolated from malignant pleural and peritoneal effusions inhibit phospholipase A2 activity in human polymorphonuclear leukocytes, Masayoshi Abe; Hisao Kitsuki; Sachiko Saruwatari; Hiroshi Asoh; Tsugutomo Sakurada; Hiroshi Kuwata; Yoshihito Nakatani; Ichiro Kudo; Tatsuo Furukawa, Cancer Letters, 121(2):155 - 161, Dec. 1997, Peer-reviewed
  • Prostaglandin E-2 amplifies cytosolic phospholipase A(2)- and cyclooxygenase-2-dependent delayed prostaglandin E-2 generation in mouse osteoblastic cells - Enhancement by secretory phospholipase A(2), M Murakami; H Kuwata; Y Amakasu; S Shimbara; Y Nakatani; G Atsumi; Kudo, I, JOURNAL OF BIOLOGICAL CHEMISTRY, 272(32):19891 - 19897, Aug. 1997, Peer-reviewed
  • Phospholipase A(2) inhibitory activity in lung cancer cell lines, M Abe; T Sakurada; H Kuwata; Y Nakatani; Kudo, I; T Furukawa, RECENT ADVANCES IN PROSTAGLANDIN, THROMBOXANE, AND LEUKOTRIENE RESEARCH, 433:343 - 345, 1997
  • Lung Cancer Cell Lines Inhibit Leukotriene B4 Production by Human Polymorphonuclear Leukocytes at the Level of Phospholipase A2, Masayoshi Abe; Hiroaki Matsuki; Mariko Domae; Hiroshi Kuwata; Ichiro Kudo; Yoichi Nakanishi; Nobuyuki Hara; Takashi Mitsuyama; Tatsuo Furukawa, American Journal of Respiratory Cell and Molecular Biology, 15(5):565 - 573, 1996, Peer-reviewed

Presentations

  • ACSL6の細胞内における機能解析, 佐久間諒、鈴木梨々、桑田浩、原俊太郎, 第69回 日本薬学会 関東支部大会, 13 Sep. 2025, 埼玉
  • LPS 誘導性全身炎症が腸管ACSL4発現に与える影響の解析, 中村壮汰、中原未遥、鈴木彩水、桑田浩、原俊太郎, 第69回 日本薬学会 関東支部大会, 13 Sep. 2025, 埼玉
  • 長鎖アシルCoA合成酵素による高度不飽和脂肪酸代謝とその影響, 桑田浩、原俊太郎, 第66回日本脂質生化学会 シンポジウム「脂質多様性の分子機序と生物学的意義」, 06 Jun. 2024
  • 長鎖アシルCoA合成酵素4の欠損がリポ多糖により惹起される炎症応答に及ぼす影響, 桑田浩、中谷絵理子、冨塚祐希、落合翔、佐々木由香、依田恵美子、原俊太郎, 日本薬学会第144年会, Mar. 2024
  • 腸上皮細胞に発現した長鎖アシルCoA合成酵素4の腸炎誘導大腸がん進展における機能解析, 落合 翔;桑田 浩;原 俊太郎, 日本生化学会大会プログラム・講演要旨集, Oct. 2023
  • 化学物質曝露に伴う肺傷害における長鎖アシルCoA合成酵素(ACSL)4の機能解析, 冨塚 祐希;桑田 浩;原 俊太郎, 脂質生化学研究, May 2023
  • 大腸がんの発症・進展における長鎖アシルCoA合成酵素-4の機能解析, 落合 翔;桑田 浩;原 俊太郎, 脂質生化学研究, May 2023
  • HK-2細胞の細胞死におけるACSL4の役割の解析, 桑田浩、冨塚祐希、原俊太郎, フォーラム2022: 衛生薬学・環境トキシコロジー, Aug. 2022
  • パラコートの肺毒性発現における長鎖アシルCoA合成酵素(ACSL)4の役割の解析, 冨塚 祐希;桑田 浩;原 俊太郎, The Journal of Toxicological Sciences, Jun. 2022
  • パラコートの毒性発現における長鎖アシルCoA合成酵素(ACSL)4の役割の解析, 冨塚 祐希;桑田 浩;原 俊太郎, 脂質生化学研究, May 2022
  • 大腸発がんにおける長鎖アシルCoA合成酵素-4の機能解析, 落合 翔;桑田 浩;原 俊太郎, 脂質生化学研究, May 2022
  • 大腸疾患における長鎖アシルCoA合成酵素-4の機能解析, 落合 翔;桑田 浩;原 俊太郎, 日本薬学会年会要旨集, Mar. 2022
  • マクロファージに発現するプロスタサイクリン合成酵素の機能解析, 山口慧士、落合翔、桑田浩、原俊太郎, 第66回日本薬学会関東支部大会, 2022
  • Deficiency of long chain acyl-CoA synthetase 4 enhances LPS-induced shock, 桑田　浩;原　俊太郎, 第94回日本生化学大会 シンポジウム「感染症と脂質代謝、オルガネラ動態」, 05 Nov. 2021, Web 開催
  • 高度不飽和脂肪酸の活性化の阻害が炎症応答に及ぼす影響, 桑田　浩;原　俊太郎, 第21回Pharmaco-Hematologyシンポジウム 「感染症と脂質代謝、オルガネラ動態」, 22 May 2021, On-line会議
  • 出血性膀胱炎におけるプロスタサイクリンの機能解析, 落合 翔;佐々木 由香;横山 知永子;桑田 浩;原 俊太郎, 脂質生化学研究, May 2021
  • 高度不飽和脂肪酸選択的アシルCoA合成酵素、ASCL4の生体内機能の解析, 桑田　浩;原　俊太郎, フォーラム2020　衛生薬学・環境トキシコロジー　シンポジウム「衛生薬学分野における脂質研究の最前線」, 04 Sep. 2020, Web開催
  • 生体内における長鎖アシルCoA合成酵素4の役割, 桑田　浩;落合　翔;原　俊太郎, 第92回日本生化学会大会, 18 Sep. 2019, 横浜
  • 高度不飽和脂肪酸選択的アシルCoA合成酵素欠損が及ぼす生体への影響, 桑田　浩;原　俊太郎, 第63回日本薬学会関東支部大会　シンポジウム「最先端の若手脂質研究」, 14 Sep. 2019, 東京
  • 炎症反応における長鎖アシルCoA合成酵素4の役割, 桑田　浩;小栗　百葉;原　俊太郎, 第61回日本脂質生化学会, 04 Jul. 2019, 札幌
  • The in vivo roles of long-chain acyl-coenzyme A synthetase 4 in phospholipid remodeling, KUWATA Hiroshi;HARA Shuntaro, 60th International Conference on the Bioscience of Lipids, 19 Jun. 2019, Tokyo
  • 組換えヒト長鎖アシルCoA合成酵素ACSL4タンパク質の性状解析, 松林 智子[新原];桑田 浩;田中 信忠;原 俊太郎;加藤 大, 昭和学士会雑誌, Apr. 2019
  • Roles of ACSL4 in inflammatory responses, 桑田　浩;小泉　朱音;加藤　卓;幸井　花子;宮崎　恵;原　俊太郎, 第91回日本生化学会大会, 26 Sep. 2018, 京都
  • マクロファージの機能における長鎖アシルCoA合成酵素4の役割, 桑田　浩;水沼　孝裕;加藤　卓;小泉　朱音;原　俊太郎, 第60回日本脂質生化学会, 31 May 2018, 東京
  • Changes in fatty acid composition of phospholipids in long-chain acyl CoA synthetase 4-deficient macrophages., 桑田　浩;水沼　孝裕;加藤　卓;小泉　朱音;原　俊太郎, 日本薬学会第138年会, 26 Mar. 2018, 金沢
  • 長鎖アシルCoA合成酵素4遺伝子欠損マウス由来マクロファージの機能解析, 桑田　浩;中谷　絵理子;水沼　孝裕;原　俊太郎, フォーラム2017　衛生薬学・環境トキシコロジー, 01 Sep. 2017, 仙台
  • エイコサノイド産生における長鎖アシルCoA合成酵素4の役割に関する研究, 桑田 浩;中谷 絵理子;原 俊太郎, 脂質生化学研究, Jun. 2017
  • マクロファージの機能制御における長鎖アシルCoA合成酵素4の役割, 桑田　浩;小泉　朱音;加藤　卓;幸井　花子;宮﨑　恵;中谷　絵理子;原　俊太郎, 日本薬学会第137年会, 25 Mar. 2017, 仙台
  • 炎症時における長鎖アシルCoA合成酵素4の機能の解明, 中谷　絵理子;桑田　浩;原　俊太郎, 日本薬学会第137年会, 25 Mar. 2017, 仙台
  • Regulatory mechanisms of chemotactic factor(s) release by intracellular phospholipase A2 in IL-1beta-stimulated rat fibroblasts, KUWATA Hiroshi;HARA Shuntaro, 6th European Workshop on Lipid Mediators, 29 Sep. 2016, Frankfurt
  • 細胞内ホスホリパーゼA2による細胞遊走因子産生の制御, 桑田　浩;平川　裕士;中谷　良人;原　俊太郎, フォーラム2016　衛生薬学・環境トキシコロジー, 10 Sep. 2016, 東京
  • リポ多糖投与により惹起される全身性炎症は長鎖アシルCoA合成酵素 4 の欠損により増悪化する, 桑田　浩;水沼　孝裕;伊藤　早紀;原　俊太郎, 日本薬学会第136年会, 29 Mar. 2016, 横浜
  • Studies on the in vivo roles of long-chain acyl CoA synthetase 4, 桑田　浩;水沼　孝裕;伊藤　早紀;原　俊太郎, フォーラム2015　衛生薬学・環境トキシコロジー, 17 Sep. 2015, 神戸
  • 長鎖アシルCoA合成酵素 4 の生体内機能の機能解析 – 1, 水沼　孝裕;伊藤　早紀;森　雅美;矢澤　将太;桑田　浩;原　俊太郎, 第59回日本薬学会関東支部大会, 12 Sep. 2015, 船橋
  • 長鎖アシルCoA合成酵素 4 の生体内機能の機能解析 – 2, 伊藤　早紀;水沼　孝裕;矢澤　将太;森　雅美;桑田　浩;原　俊太郎, 第59回日本薬学会関東支部大会, 12 Sep. 2015, 船橋
  • Studies on the mechanism of chemokine expression by intracellular phospholipase A2, 平川　裕士;桑田　浩;原　俊太郎, 日本薬学会第135年会, 28 Mar. 2015, 神戸
  • Inhibition of acyl-CoA synthetase perturbs arachidonic acid metabolism, KUWATA Hiroshi;HARA Shuntaro, 6th international conference on Phospholipase A2 and Lipid Mediators, 11 Feb. 2015, Tokyo
  • 長鎖アシル CoA 合成酵素の阻害による脂肪酸代謝変動の解析, 桑田　浩;庄司　知紘;福島　有彩;原　俊太郎, 第87回日本生化学会大会, 16 Oct. 2014, 京都
  • Inhibition of Acyl-CoA synthetase activity perturbs fatty acid metabolism, 桑田　浩;島田　浩明;庄司　知紘;福島　有彩;原　俊太郎, フォーラム2014　衛生薬学・環境トキシコロジー, 20 Sep. 2014, つくば
  • Alteration of fatty acid metabolic profiles by the inhibition of Acyl-CoA synthetase, 桑田　浩;島田　浩明;福島　有彩;原　俊太郎, 日本薬学会第134年会, 28 Mar. 2014, 熊本

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