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Mukudai Yoshiki

■FacultyOral and Maxillofacial Surgery
■PositionSenior Lecturer
Last Updated :2025/07/03

Researcher

基本情報

Profile and Settings

  • 氏名

    Mukudai Yoshiki

Identifiers

  • 研究者番号

    50325099

  • ORCID ID

    0000-0002-9600-4430

  • J-Global ID

    200901041623062879

Affiliation

  • Oral and Maxillofacial Surgery, Senior Lecturer

Location

  • Dental Hospital

Degree

  • Doctor of Dental Science, Osaka University, Mar. 1999

Achievements

Published Papers

  • Pleomorphic adenoma gene 1 (PLAG1) protects p53-/- myoepithelial cells from mitochondria-related apoptosis caused by hypoxia, Nodoka Kindaichi , Yoshiki Mukudai , Yuzo Abe , Masataka Watanabe , Maki Nara , Konomi Yamada , Asami Houri , Toshikazu Shimane , Tatsuo Shirota, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 37(4):654 - 331, Jun. 2025, Peer-reviewed, DOI:https://doi.org/10.1016/j.ajoms.2025.01.005
  • Tumor Protein D53 (TPD53): Involvement in Malignant Transformation of Low-Malignant Oral Squamous Cell Carcinoma Cells, Masataka Watanabe, Yoshiki Mukudai*, Nodoka Kindaichi, Maki Nara, Konomi Yamada, Yuzo Abe, Asami Houri, Toshikazu Shimane, Tatsuo Shirota, Biomedicines, 12(12):2725, Nov. 2024, Peer-reviewed, DOI:https://doi.org/10.3390/biomedicines12122725
  • Suprabasin enhances the invasion, migration, and angiogenic ability of oral squamous cell carcinoma cells under hypoxic conditions., Houri Asami;Mukudai Yoshiki;Abe Yuzo;Watanabe Masataka;Nara Maki;Miyamoto Saya;Kurihara Mai;Shimane Toshikazu;Shirota Tatsuo, Oncology reports, 49(5), Mar. 2023, Peer-reviewed
  • Tumor protein D54: A promising marker of mucoepidermoid carcinoma, YASO Atsutoshi;KAMATANI Takaaki;MUKUDAI Yoshiki;ABE Yuzo;SHIROTA Tatsuo, Showa Univ J Med Sci, 34(1):1 - 10, Mar. 2022, Peer-reviewed
  • Autophagy Prevents Osteocyte Cell Death under Hypoxic Conditions., KURIHARA Mai;MUKUDAI Yoshiki;WATANABE Hitoshi;ASAKURA Mariko;ABE Yuzo;HOURI Asami;CHIKUDA Junichiro;SHIMANE Toshikazu;SHIROTA Tatsuo, Cells Tissues Organs, 210(5月6日):326 - 338, Dec. 2021, Peer-reviewed
  • Combinational Anti-tumor Effects of Chemicals from Paeonia lutea Leaf Extract in Oral Squamous Cell Carcinoma Cells., Shinsuke Nakamura; Yoshiki Mukudai; Junichiro Chikuda; Meilin Zhang; Hideyuki Shigemori; Kazunaga Yazawa; Seiji Kondo; Toshikazu Shimane; Tatsuo Shirota, Anticancer research, 41(12):6077 - 6086, Dec. 2021, Peer-reviewed
  • Tumor protein D52 is upregulated in oral squamous carcinoma cells under hypoxia in a hypoxia-inducible-factor-independent manner and is involved in cell death resistance, ABE Yuzo;MUKUDAI Yoshiki;KURIHARA Mai;HOURI Asami;CHIKUDA Junichiro;YASO Atsutoshi;KATO Kosuke;SHIMANE Toshikazu;SHIROTA Tatsuo, Cell Biosci, 11(1):122, Jul. 2021, Peer-reviewed
  • Combinational Anti-tumor Effects of Chemicals from Paeonia lutea Leaf Extract in Oral Squamous Cell Carcinoma Cells., Nakamura Shinsuke, Mukudai Yoshiki, Chikuda Junichiro, Zhang Meilin, Shigemori Hideyuki, Yazawa Kazunaga, Kondo Seiji, Shimane Toshikazu, Shirota Tatsuo, Anticancer research, 41(12), 2021, Peer-reviewed
  • CD44s Induces miR-629-3p Expression in Association with Cisplatin Resistance in Head and Neck Cancer Cells, CHIKUDA Junichiro;OTSUKA Kurataka;SHIMOMURA Iwao;ITO Kagenori;MIYAZAKI Hiroaki;TAKAHASHI Ryou-u;NAGASAKI Masahiro;MUKUDAI Yoshiki;OCHIYA Takahiro;SHIMANE Toshikazu;SHIROTA Tatsuo;YAMAMOTO Yusuke, Cancers (Basel), 12(4):E856, Apr. 2020, Peer-reviewed
  • 唾液腺腫瘍におけるTumor Protein D52ファミリーの発現様式の検索, 八十 篤聡;椋代 義樹;代田 達夫, 日本口腔科学会雑誌, 67(2):140, Jul. 2018, Peer-reviewed
  • Tumor Proteins D52 and D54 Have Opposite Effects on the Terminal Differentiation of Chondrocytes, ITO Chihiro;MUKUDAI Yoshiki;ITOSE Masakatsu;KATO Kosuke;MOTOHASHI Hiromi;SHIMANE Toshikazu;KONDO Seiji;SHIROTA Tatsuo, Biomed Res Int, 2017:6014278, Jul. 2017, Peer-reviewed
  • Opposite effects of tumor protein D (TPD) 52 and TPD54 on oral squamous cell carcinoma cells, KATO Kosuke;MUKUDAI Yoshiki;MOTOHASHI Hiromi;ITO Chihiro;KAMOSHIDA ShInnosuke;SHIMANE Toshikazu;KONDO Seiji;SHIROTA Tatsuo, Int J Oncol, 50(5):1634 - 1646, May 2017, Peer-reviewed
  • Tumor protein D52 expression is post-transcriptionally regulated by T-cell intercellular antigen (TIA) 1 and TIA-related protein via mRNA stability, MOTOHASHI Hiromi;MUKUDAI Yoshiki;ITO Chihiro;KATO Kosuke;SHIMANE Toshikazu;KONDO Seiji;SHIROTA Tatsuo, Biochem J, 474(10):1669 - 1687, May 2017, Peer-reviewed
  • TPD52遺伝子の転写後遺伝子発現の解析, 椋代 義樹;代田 達夫, 口腔組織培養学会誌, 26(1):17, Mar. 2017
  • TPD52遺伝子の発現はTIA-1及びTIARによってmRNAの安定性を介して転写後制御される, 本橋 宏美;椋代 義樹, Journal of Oral Biosciences Supplement, 2016:292, Sep. 2016
  • TPD52ファミリー遺伝子の軟骨細胞における増殖・分化に対する役割の検索, 椋代 義樹; 伊藤 千洋; 加藤 光佑; 本橋 宏美; 近藤 誠二; 代田 達夫, 日本骨代謝学会学術集会プログラム抄録集, 34回:222 - 222, Jul. 2016
  • Clinicopathological implications of vascular endothelial growth factor 165b expression in oral squamous cell carcinoma stroma., NAGASAKI Masahiro;KONDO Seiji;MUKUDAI Yoshiki;KAMATANI Takaaki;AKIZUKI Ayako;YASO Atsutoshi;SHIMANE Toshikazu;SHIROTA Tatsuo, Oncol Rep, 36(1):573 - 581, Jul. 2016, Peer-reviewed
  • Methanol and butanol extracts of Paeonia lutea leaves repress metastasis of squamous cell carcinoma, MUKUDAI Yoshiki;ZHANG Meilin;SHIOGAMA Sunao;KONDO Seiji;ITO Chihiro;MOTOHASHI Hiromi;KATO Kosuke;FUJII Miharu;SHINTANI Satoru;SHIGEMORI Hideyuki;YAZAWA Kazunaga;SHIROTA Tatsuo, Evid Based Complement Alternat Med, 2016:6087213, May 2016, Peer-reviewed
  • TPD52mRNAの転写後遺伝子発現制御機構の検索, 本橋 宏美; 椋代 義樹; 加藤 光佑; 伊藤 千洋; 近藤 誠二; 代田 達夫, 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 88回・38回:[1P0755] - [1P0755], Dec. 2015
  • TPD52ファミリータンパクの遺伝子発現制御の検索, 本橋 宏美; 椋代 義樹; 代田 達夫; 近藤 誠二, Journal of Oral Biosciences Supplement, 2015:181 - 181, Sep. 2015
  • TPD52ファミリータンパクの遺伝子発現制御の検索, 本橋 宏美; 椋代 義樹; 代田 達夫; 近藤 誠二, Journal of Oral Biosciences Supplement, 2015:272 - 272, Sep. 2015
  • Paeonia lutea葉の抽出物による扁平上皮癌の増殖・転移抑制効果, 椋代 義樹; 本橋 宏美; 代田 達夫; 近藤 誠二; 矢澤 一良; 繁森 英幸; Zhang Meilin, Journal of Oral Biosciences Supplement, 2015:455 - 455, Sep. 2015
  • 口腔扁平上皮癌細胞の増殖・浸潤・転移に対するTPD52ファミリーの相互作用の検索, 加藤 光佑;椋代 義樹;本橋 宏美;伊藤 千尋, 日本口腔科学会雑誌, 64(2):152, Jul. 2015
  • TPDファミリータンパクの遺伝子発現制御の検索, 本橋 宏美; 椋代 義樹; 伊藤 千尋; 加藤 光佑; 近藤 誠二; 代田 達夫, 日本口腔科学会雑誌, 64(2):151 - 152, Jul. 2015
  • A Combination of Low-Intensity Pulsed Ultrasound and Nanohydroxyapatite Concordantly Enhances Osteogenesis of Adipose-Derived Stem Cells From Buccal Fat Pad., NAGASAKI Rika;MUKUDAI Yoshiki;YOSHIZAWA Yasumasa;NAGASAKI Masahiro;SHIOGAMA Sunao;SUZUKI Maiko;KONDO Seiji;SHINTANI Satoru;SHIROTA Tatsuo, Cell Med, 7(3):123 - 131, Apr. 2015, Peer-reviewed
  • 頬脂肪体由来脂肪幹細胞の骨形成におけるLow Intensity Pulsed Ultrasoundとナノハイドロキシアパタイトの影響, 長崎 理佳; 椋代 義樹; 吉澤 泰昌; 鈴木 麻衣子; 代田 達夫; 近藤 誠二; 新谷 悟, 口腔組織培養学会誌, 23(1):134 - 135, Nov. 2014
  • Defferential expression of vascular endothelial growth factor in high- and low-metastasis cell lines of salivary gland adenoid cystic carcinoma, KONDO Seiji;MUKUDAI Yoshiki;SOGA Daisuke;NISHIDA Takashi;TAKIGAWA Masaharu;SHIROTA Tatsuo, Anticancer Res, 34(2):671 - 677, Feb. 2014, Peer-reviewed
  • Potential anti-osteoporotic effects of herbal extracts on osteoclasts, osteoblasts and chondrocytes in vitro., MUKUDAI Yoshiki;KONDO Seiji;KOYAMA Tomoyuki;LI Chunnan;BANKA Seika;KOGURE Akiko;YAZAWA Kazunaga;SHINTANI Satoru, BMC Complement Altern Med, 14:29, Jan. 2014, Peer-reviewed
  • Root bark extracts of Juncus effusus and Paeonia suffruticosa protect salivary gland acinar cells from apoptotic cell death induced by cis-platinum (II) diammine dichloride, Yoshiki Mukudai; Seiji Kondo; Sunao Shiogama; Tomoyuki Koyama; Chunnan Li; Kazunaga Yazawa; Satoru Shintani, ONCOLOGY REPORTS, 30(6):2665 - 2671, Dec. 2013
  • Tumor protein D54 is a negative regulator of extracellular matrix-dependent migration and attachment in oral squamous cell carcinoma-derived cell lines, Yoshiki Mukudai; Seiji Kondo; Atsushi Fujita; Yasuto Yoshihama; Tatsuo Shirota; Satoru Shintani, CELLULAR ONCOLOGY, 36(3):233 - 245, Jun. 2013
  • 高転移性、低転移性腺様嚢胞癌細胞株におけるVEGF発現の差異, 近藤 誠二; 椋代 義樹; 曽我 大輔; 新谷 悟, 頭頸部癌, 39(2):174 - 174, May 2013
  • 苦楝皮、醋延胡索、および白薇抽出液の骨粗鬆症治療への基礎的研究, 椋代 義樹; 近藤 誠二; 新谷 悟, 日本骨代謝学会学術集会プログラム抄録集, 31回:98 - 98, May 2013
  • 新たな骨粗鬆症治療薬となりうる生薬エキスの検索, 椋代 義樹; 近藤 誠二; 小山 智之; Li Chunnan; 矢澤 一良; 新谷 悟, 口腔組織培養学会誌, 22(1):17 - 18, Feb. 2013
  • 口腔扁平上皮癌細胞における牡丹皮の抗腫瘍作用, 近藤 誠二; 李 春男; 矢澤 一良; 椋代 義樹; 佐藤 大典; 吉濱 泰斗; 代田 達夫; 新谷 悟, 口腔組織培養学会誌, 22(1):23 - 24, Feb. 2013
  • The potential anticancer activity of extracts derived from the roots of Scutellaria baicalensis on human oral squamous cell carcinoma cells., Sato D; Kondo S; Yazawa K; Mukudai Y; Li C; Kamatani T; Katsuta H; Yoshihama Y; Shirota T; Shintani S, Molecular and clinical oncology, 1(1):105 - 111, Jan. 2013
  • A combination of chemical and mechanical stimuli enhances not only osteo-but also chondro-differentiation in adipose-derived stem cells, Seika Banka; Yoshiki Mukudai; Yasuto Yoshihama; Tatsuo Shirota; Seiji Kondo; Satoru Shintani, Journal of Oral Biosciences, 54(4):188 - 195, Nov. 2012
  • The Root Bark of Paeonia moutan is a Potential Anticancer Agent in Human Oral Squamous Cell Carcinoma Cells, Chunnan Li; Kazunaga Yazawa; Seiji Kondo; Yoshiki Mukudai; Daisuke Sato; Yuji Kurihara; Takaaki Kamatani; Satoru Shintani, Anticancer Research, 32(7):2625 - 2630, Jul. 2012
  • 天然生薬エキスの口腔癌治療創薬への可能性について, 佐藤 大典; 近藤 誠二; 矢澤 一良; 椋代 義樹; 吉濱 泰斗; 代田 達夫; 新谷 悟, 口腔組織培養学会誌, 21(1):7 - 8, Feb. 2012
  • 天然生薬による口腔癌治療創薬の試み, 佐藤 大典; 近藤 誠二; 椋代 義樹; 代田 達夫; 新谷 悟, 日本口腔外科学会雑誌, 57(Suppl.):188 - 188, Sep. 2011
  • ニワトリCCN1のmRNAの翻訳領域に存在するGC-rich配列の転写後遺伝子発現制御への役割, 椋代 義樹; 近藤 誠二; 吉濱 泰斗; 代田 達夫; 新谷 悟, 日本口腔外科学会雑誌, 57(Suppl.):242 - 242, Sep. 2011
  • Evaluation of Anticancer Activities of Benzo[c]phenanthridine Alkaloid Sanguinarine in Oral Squamous Cell Carcinoma Cell Line, Hikari Tsukamoto; Seiji Kondo; Yoshiki Mukudai; Tatsuhito Nagumo; Arisa Yasuda; Yuji Kurihara; Takaaki Kamatani; Satoru Shintani, Anticancer Research, 31(9):2841 - 2846, Sep. 2011
  • 新たな骨粗鬆症治療薬としての生薬の破骨細胞、骨芽細胞および軟骨細胞への効果, 椋代 義樹; 番家 政香; 近藤 誠二; 矢澤 一良; 新谷 悟, 日本骨代謝学会学術集会プログラム抄録集, 29回:233 - 233, Jul. 2011
  • 脂肪幹細胞(ADSC)から骨形成細胞への分化に対する化学的、機械的刺激の影響, 番家 政香; 椋代 義樹; 吉濱 泰斗; 代田 達夫; 近藤 誠二; 新谷 悟, 日本骨代謝学会学術集会プログラム抄録集, 29回:265 - 265, Jul. 2011
  • Anti-tumor activity of dehydroxymethylepoxyquinomicin against human oral squamous cell carcinoma cell lines in vitro and in vivo, Arisa Yasuda; Seiji Kondo; Tatsuhito Nagumo; Hikari Tsukamoto; Yoshiki Mukudai; Kazuo Umezawa; Satoru Shintani, ORAL ONCOLOGY, 47(5):334 - 339, May 2011
  • 脂肪幹細胞(ADSC)から骨形成細胞への分化に対する化学的、機械的刺激の影響, 番家 政香; 椋代 義樹; 近藤 誠二; 新谷 悟, 口腔組織培養学会誌, 20(1):3 - 4, Feb. 2011
  • Na+-K+ATPase阻害剤Sanguinarineの口腔扁平上皮癌に対する抗腫瘍効果, 塚本 光; 椋代 義樹; 南雲 達人; 安田 有沙; 近藤 誠二; 新谷 悟, 口腔組織培養学会誌, 20(1):17 - 18, Feb. 2011
  • Binding of glyceraldehyde-3-phosphate dehydrogenase to the cis-acting element of structure-anchored repression in ccn2 mRNA, Seiji Kondo; Satoshi Kubota; Yoshiki Mukudai; Takashi Nishida; Yasuto Yoshihama; Tatsuo Shirota; Satoru Shintani; Masaharu Takigawa, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 405(3):382 - 387, Feb. 2011
  • A Coding RNA Segment That Enhances the Ribosomal Recruitment of Chicken ccn1 mRNA, Yoshiki Mukudai; Satoshi Kubota; Takanori Eguchi; Kumi Sumiyoshi; Danilo Janune; Seiji Kondo; Satoru Shintani; Masaharu Takigawa, JOURNAL OF CELLULAR BIOCHEMISTRY, 111(6):1607 - 1618, Dec. 2010
  • 天然生薬エキスによる口腔癌治療創薬への挑戦, 近藤 誠二; 矢澤 一良; 椋代 義樹; Lee Chunnan; 佐藤 大典; 塩竈 素直; 吉濱 泰斗; 代田 達夫; 新谷 悟, 日本統合医療学会誌, 3(2):85 - 85, Nov. 2010
  • 新たな骨粗鬆症治療薬としての生薬のin vitroでの基礎的検討, 椋代 義樹; 矢澤 一良; 木暮 暁子; 番家 政香; 塚本 光; 安田 有紗; 檀 知里; 吉濱 泰斗; 代田 達夫; 近藤 誠二; 新谷 悟, 日本統合医療学会誌, 3(2):88 - 88, Nov. 2010
  • 口腔扁平苔癬に対する低分子フコイダン投与についての臨床的検討, 新谷 悟; 内田 真紀子; 椋代 義樹; 吉濱 泰斗; 代田 達夫; 近藤 誠二, 日本統合医療学会誌, 3(2):111 - 111, Nov. 2010
  • Nucleophosmin/B23: A Multifunctional Regulator that Determines the Fate of CCN2 mRNA, Satoshi Kubota; Yoshiki Mukudai; Harumi Kawaki; Seiji Kondo; Takanori Eguchi; Kumi Sumiyoshi; Toshihiro Ohgawara; Tsuyoshi Shimo; Masaharu Takigawa, CCN PROTEINS IN HEALTH AND DISEASE: AN OVERVIEW OF THE FIFTH INTERNATIONAL WORKSHOP ON THE CCN FAMILY OF GENES, :41 - +, 2010
  • Novel Transcriptional Regulation of CCN2/CTGF by Nuclear Translocation of MMP3, Takanori Eguchi; Satoshi Kubota; Kazumi Kawata; Yoshiki Mukudai; Junji Uehara; Toshihiro Ohgawara; Soichiro Ibaragi; Akira Sasaki; Takuo Kuboki; Masaharu Takigawa, CCN PROTEINS IN HEALTH AND DISEASE: AN OVERVIEW OF THE FIFTH INTERNATIONAL WORKSHOP ON THE CCN FAMILY OF GENES, :255 - +, 2010
  • 軟骨細胞におけるCCN2遺伝子の転写後調節機構におけるNucleophosmin/B23の機能的意義, 住吉 久美; 久保田 聡; 椋代 義樹; 近藤 誠二; 川木 晴美; 江口 傑徳; 大河原 敏博; 山城 隆; 滝川 正春, 日本生化学会大会プログラム・講演要旨集, 82回:3T18a - 8, Sep. 2009
  • Nucleophosmin/B23によるChicken CCN2遺伝子の軟骨細胞特異的転写後調節, 住吉 久美; 久保田 聡; 椋代 義樹; 近藤 誠二; 川木 晴美; 江口 傑徳; 山城 隆; 滝川 正春, Journal of Oral Biosciences, 51(Suppl.):105 - 105, Aug. 2009
  • Posttranscriptional regulation of chicken ccn2 gene expression by nucleophosmin/B23 during chondrocyte differentiation, Yoshiki Mukudai; Satoshi Kubota; Harumi Kawaki; Seiji Kondo; Takanori Eguchi; Kumi Sumiyoshi; Toshihiro Ohgawara; Tsuyoshi Shimo; Masaharu Takigawa, MOLECULAR AND CELLULAR BIOLOGY, 28(19):6134 - 6147, Oct. 2008
  • Novel transcription factor-like function of human matrix metalloproteinase 3 regulating the CTGF/CCN2 gene, Takanori Eguchi; Satoshi Kubota; Kazumi Kawata; Yoshiki Mukudai; Junji Uehara; Toshihiro Ohgawara; Soichiro Ibaragi; Akira Sasaki; Takuo Kuboki; Masaharu Takigawa, MOLECULAR AND CELLULAR BIOLOGY, 28(7):2391 - 2413, Apr. 2008
  • Nuclear protein TIA-1 regulates COL2A1 alternative splicing and interacts with precursor mRNA and genomic DNA, Audrey McAlinden; Li Liang; Yoshiki Mukudai; Toshihiro Imamura; Linda J. Sandell, JOURNAL OF BIOLOGICAL CHEMISTRY, 282(33):24444 - 24454, Aug. 2007
  • Different transcriptional strategies for ccn2/ctgf gene induction between human chondrocytic and breast cancer cell lines, Takanori Eguchi; Satoshi Kubota; Kazumi Kawata; Yoshiki Mukudai; Toshihiro Ohgawara; Kohei Miyazono; Kyouji Nakao; Seiji Kondo; Masaharu Takigawa, BIOCHIMIE, 89(3):278 - 288, Mar. 2007
  • Post-transcriptional Regulation of Chicken ccn2 Gene by Interaction between RNA cis-element and trans-factor during Differentiation of Chondrocytes, Mukudai Yoshiki, Japanese Journal of Oral Biology, 49(1):15 - 22, 2007
  • Dopamine Receptor Presence in the Rat Area Postrema Identified by RT-PCR, Immunohistochemistry, and In Situ Hybridization, Shunji Izawa; Tomoichiro Yamaai; Yoshiki Mukudai; Kozo Yamaji; Yoshihiro Nishitani; Toshiyuki Itota; Ryuji Matsuo; Masaharu Takigawa; Masahiro Yoshiyama, Journal of Oral Biosciences, 49(4):259 - 268, 2007
  • 硬組織再生研究の最前線 CCNファミリータンパク質の内軟骨性骨化制御機構と骨・軟骨再生作用, 久保田 聡; 椋代 義樹; 菊池 剛; 大野 充昭; 川木 晴美; 柳田 剛志; 西田 崇; 田畑 泰彦; 窪木 拓男; 滝川 正春, 日本骨代謝学会学術集会プログラム抄録集, 24回:72 - 72, Jul. 2006, Peer-reviewed
  • Hypoxic regulation of stability of connective tissue growth factor/CCN2 mRNA by 3 '-untranslated region interacting with a cellular protein in human chondrosarcoma cells, S Kondo; S Kubota; Y Mukudai; N Moritani; T Nishida; H Matsushita; S Matsumoto; T Sugahara; M Takigawa, ONCOGENE, 25(7):1099 - 1110, Feb. 2006
  • Novel angiogenic inhibitor DN-9693 that inhibits post-transcriptional induction of connective tissue growth factor (CTGF/CCN2) by vascular endothelial growth factor in human endothelial cells, S Kondo; N Tanaka; S Kubota; Y Mukudai; G Yosimichi; T Sugahara; M Takigawa, MOLECULAR CANCER THERAPEUTICS, 5(1):129 - 137, Jan. 2006
  • Translational repression by the cis-acting element of structure-anchored repression (CAESAR) of human ctgf/ccn2 mRNA, S Kubota; Y Mukudai; NH Moritani; K Nakao; K Kawata; M Takigawa, FEBS LETTERS, 579(17):3751 - 3758, Jul. 2005
  • 低酸素組織,軟骨における肥大軟骨特異的蛋白24/結合組織成長因子/CCNファミリー2mRNAの安定化機構 核および細胞質タンパク結合を介した3'-非翻訳領域(UTR)の関与, 近藤 誠二; 久保田 聡; 椋代 義樹; 森谷 徳文; 西田 崇; 菅原 利夫; 滝川 正春, 日本骨代謝学会学術集会プログラム抄録集, 23回:159 - 159, Jun. 2005
  • Regulation of chicken ccn2 gene by interaction between RNA cis-element and putative trans-factor during differentiation of chondrocytes, Y Mukudai; S Kubota; T Eguchi; S Kondo; K Nakao; M Takigawa, JOURNAL OF BIOLOGICAL CHEMISTRY, 280(5):3166 - 3177, Feb. 2005
  • Conserved repressive regulation of connective tissue growth factor/hypertrophic chondrocyte-specific gene 24 (ctgf/hcs24) enabled by different elements and factors among vertebrate species, Y Mukudai; S Kubota; M Takigawa, BIOLOGICAL CHEMISTRY, 384(1):1 - 9, Jan. 2003
  • 多機能成長因子CTGF/Hcs24遺伝子の転写後制御エレメント,CAESARの作用機序, 久保田 聡; 近藤 誠二; 椋代 義樹; 江口 傑徳; 服部 高子; 中西 徹; 滝川 正春, 生化学, 73(8):710 - 710, Aug. 2001
  • 内軟骨性骨化における軟骨細胞の増殖,および分化に対するBMPシグナルの役割に関する研究, 大阪大学歯学雑誌, 44(2):1 - 19, 2000
  • Role of chondroitin sulfate hyaluronan interactions in the viscoelastic properties of extracellular matrices and fluids, M Nishimura; WQ Yan; Y Mukudai; S Nakamura; K Nakamasu; M Kawata; T Kawamoto; M Noshiro; T Hamada; Y Kato, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1380(1):1 - 9, Mar. 1998
  • Bone morphogenetic protein signaling is required for maintenance of differentiated phenotype, control of proliferation, and hypertrophy in chondrocytes, M Enomoto-Iwamoto; M Iwamoto; Y Mukudai; Y Kawakami; T Nohno; Y Higuchi; S Takemoto; H Ohuchi; S Noji; K Kurisu, JOURNAL OF CELL BIOLOGY, 140(2):409 - 418, Jan. 1998
  • Effects of hyaluronic acid on the release of cartilage matrix proteoglycan and fibronectin from the cell matrix layer of chondrocyte cultures: interactions between hyaluronic acid and chondroitin sulfate glycosaminoglycan, Kato Y; Mukudai Y; Okimura A; Shimazu A; Nakamura S, The Journal of rheumatology. Supplement, 43:158 - 9, 1995

Presentations

  • Tumor Protein D53 (TPD53) is involved in malignant transformation of low-malignant oral squamous cell carcinoma cells., Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Maki Nara, Konomi Yamada, Yuzo Abe, Asami Houri, Toshikazu Shimane, Tatsuo Shirota, The 47th annual meeting of the Molecular Biology Society of Japan, 28 Nov. 2024, The Molecular Biology Society of Japan, Fukuoka, Japan
  • Tumor Protein D53 Increases Cell Proliferation and Invasion in Low-Malignant Oral Squamous Cell Carcinoma Cells., Masataka Watanabe, Yoshiki Mukudai, Nodoka Kindaichi, Maki Nara, Konomi Yamada, Yuzo Abe, Asami Houri, Tatuo Shirota, The 69th Congress of the Japanese Society of Oral and Maxillofacial Surgeons, 22 Nov. 2024, The Japanese Society of Oral and Maxillofacial Surgeons, Yokohama, Japan
  • Tumor protein D53 (TPD53) is involved in malignant transformation of low-malignant oral squamous-cell carcinoma cells, Masataka Watanabe, Yoshiki Mukudai, Kindaichi Nodoka, Maki Nara, Konomi Yamada, Yuzo Abe, Asami Houri, Tatuo Shirota, 27th EACMFS Congress, 17 Sep. 2024, European Association for Oral and Cranio-Maxillo-Facial Surgery, Rome, Italy
  • Effects of hypoxia in myoepithelial cells, Nodoka Kindaichi, Yoshiki Mukudai, Masataka Watanabe, Yuzo Abe, Maki Nara, Konomi Yamada, Tatsuo Shirota, 27th EACMFS Congress, 17 Sep. 2024, European Association for Oral and Cranio-Maxillo-Facial Surgery, Rome, Italy
  • Suprabasin(SBSN) enhances cell infiltration and vascular inductionattraction under hypoxia in OSCC cells., Yoshiki Mukudai, Asami Houri, Yuzo Abe, Mai Kurihara , Masataka Watanabe, Maki Nara, Nodoka Kindaichi, Saya Miyamoto, Toshikazu Shimane and Tatsuo Shirota, 46th Annual Meeting of the Molecular Biology Society of Japan, 07 Dec. 2023, The Molecular Biology Society of Japan, Kobe, Japan
  • Tumor protein D52 is upregulated in oral squamous carcinoma cells under hypoxia in a hypoxia-inducible-factor-independent manner and is involved in cell death resistance, Yuzo Abe, Yoshiki Mukudai, Mai Kurihara, Asami Houri, Tatsuo Shirota, 25th International Conference on Oral Maxillofacial Surgery, 09 Jun. 2023, International Association of Oral and Maxillofacial Surgeons, Vancouver, Canada
  • Suprabasin enhances the invasion, migration, and angiogenic ability of oral squamous cell carcinoma cells under hypoxic conditions, Asami Noro，Yoshiki Mukudai，Yuzo Abe，Tatsuo Shirota, 25th International Conference on Oral Maxillofacial Surgery, 09 Jun. 2023, International Association of Oral and Maxillofacial Surgeons, Vancouver, Canada
  • Suprabasin (SBSN) enhances cell immigration and vascular induction in OSCC cells under hypoxia., Asami Houri; Yoshiki Mukudai; Masataka Watanabe; Yzo Abe; Mai Kobashi; Tatsuo Shirota, The 67th Congress of the Japanese Society of Oral and Maxillofacial Surgery, 05 Nov. 2022, The Japanese Society of Oral and Maxillofacial Surgery, Chiba, Japan
  • Tumor protein D52 is upregulated in oral squamous carcinoma cells under hypoxia in a hypoxia inducible factor independent manner and is involved in cell death resistance, Yuzo Abe; Yoshiki Mukudai; Mai Kurihara; Asami Houri; Tatsuo Shirota, The 40th Annual meeting of JAPAN HUMAN CELL SOCIETY, 23 Oct. 2022, JAPAN HUMAN CELL SOCIETY, Osaka, Japan
  • Expression of the TPD52 gene is post-transcriptionally regulated via mRNA stability by TIA-1 and TIAR., Yoshiki MukudaiI; Yuzo Abe; Tatsuo Shirota, The 40th Annual meeting of JAPAN HUMAN CELL SOCIETY, 23 Oct. 2022, JAPAN HUMAN CELL SOCIETY, Osaka, Japan
  • Tumor protein D52 is upregulated in oral squamous carcinoma cells under hypoxia in a hypoxia-inducible-factor-independent manner and is involved in cell death resistance, 椋代　義樹;安部　勇蔵;栗原　舞;祝部　亜紗美;筑田　洵一郎;八十　篤聡;代田　達夫, 第44回日本分子生物学会年会, 01 Dec. 2021, 横浜・オンライン
  • 低酸素環境下における骨細胞はオートファジーによって細胞死が抑制される, 栗原　舞;椋代　義樹;安部　勇蔵;祝部　亜紗美;代田　達夫, 第66回日本口腔外科学会総会・学術大会, 12 Nov. 2021, 千葉およびライブ配信
  • TPD52は低酸素下の口腔扁平上皮癌細胞でHIF1非依存的に亢進し細胞死抵抗性に関与する, 安部　勇蔵;椋代　義樹;栗原　舞;祝部　亜紗美;代田　達夫, 第66回日本口腔外科学会総会・学術大会, 12 Nov. 2021, 千葉およびライブ配信
  • Autophagy prevents osteocytes under a hypoxic condition from cell death., 栗原　舞;椋代　義樹;安部　勇蔵;祝部　亜紗美;代田　達夫, 第65回日本口腔外科学会総会・学術大会, 13 Nov. 2020, on Line LIVE, on Demand開催
  • TPD52 is up-regulated on OSCC cells in hypoxia by a HIF-independent manner and is involved in resistance from cell death., 安部　勇蔵;椋代　義樹;栗原　舞;祝部　亜紗美;代田　達夫, 第65回日本口腔外科学会総会・学術大会, 13 Nov. 2020, on Line LIVE, on Demand開催
  • Analysis of pharmacological effects from Paeonia lutea extracts on antitumor effect in squamous cell carcinoma, 中村　真輔;椋代　義樹;筑田　洵一郎;鎌谷　宇明;嶋根　俊和;代田　達夫, 第64回日本口腔外科学会総会・学術大会, 25 Oct. 2019, 札幌
  • Elucidating miRNA associated with cisplatin resistance in oral cancer cells, 筑田　洵一郎;椋代　義樹;中村　真輔;鎌谷　宇明;嶋根　俊和;代田　達夫, 第64回日本口腔外科学会総会・学術大会, 25 Oct. 2019, 札幌
  • Expression of TPD52 gene undergoes a negative feed-back via its mRNA stability, 椋代　義樹;本橋　宏美;代田　達夫, 2017年度生命科学系学会合同年次大会（第40回日本分子生物学会年会・第90回日本生化学会大会）, 06 Dec. 2017, 神戸
  • Roles of TPD52 family genes on terminal differentiation of chondrocytes, ITO Chihiro;MUKUDAI Yoshiki;ITOSE Masakatsu;KATO Kosuke;MOTOHASHI Hiromi;SHIROTA Tatsuo, 第65回国際歯科研究学会日本部会総会・学術大会, 19 Nov. 2017, 東京
  • Tumor protein D52 expression is post-transcriptional regulated via mRNA stability, MUKUDAI Yoshiki;MOTOHASHI Hiromi;ITO Chihiro;KATO Kosuke;SHIMANE Toshikazu;KONDO Seiji;SHIROTA Tatsuo, 第65回国際歯科研究学会日本部会総会・学術大会, 18 Nov. 2017, 東京
  • Opposite effects of TPD52 and TPD54 on oral squamous cell carcinoma cells, MUKUDAI Yoshiki;KATO Kousuke;MOTOHASHI Hiromi;ITO Chihiro;KAMOSHIDA Shinnosuke;SHIMANE Toshikazu;KONDO Seiji;SHIROTA Tatsuo, 22nd World Congress on Advances in Oncology and 20th International Symposium on Molecular Medicine, 07 Oct. 2017, Athens
  • The 3’-UTR of TPD52 family mRNA is post-transcriptional regulated on its gene expression, 本橋　宏美;椋代　義樹;加藤　光佑;伊藤　千洋;近藤　誠二;嶋根　俊和;代田　達夫, 第39回日本分子生物学会年会, 01 Dec. 2016, 横浜
  • TPD52遺伝子の転写後遺伝子発現の解析, 椋代　義樹;代田　達夫, 第53回日本口腔組織培養学会学術大会・総会, 18 Nov. 2016, 金沢
  • TPD52遺伝子の発現はTIA-1およびTIARによってmRNAの安定性を介して転写後制御される, 本橋　宏美;椋代　義樹, 第58回歯科基礎医学会年会, 25 Aug. 2016, 札幌
  • Roles of TPD52 family genes on growth and differentiation of chondrocytes, 椋代　義樹;伊藤　千洋;加藤　光佑;本橋　宏美;近藤　誠二;代田　達夫, 第34回日本骨代謝学会学術集会・第3回アジア太平洋骨代謝学会議, 23 Jul. 2016, 大阪
  • Post-transcriptional Regulation of TPD52 mRNA, 本橋　宏美;椋代　義樹;加藤　光佑;伊藤　千洋;近藤　誠二;代田　達夫, BMB2015(第38回日本分子生物学会年会・第88回日本生化学会大会合同大会), 01 Dec. 2015, 神戸
  • The 3′-UTR of TPD family mRNA is post-transcriptional regulation on its gene expression, MOTOHASHI Hiromi;MUKUDAI Yoshiki;Ito Chihiro;KATO Kosuke;KONDO Seiji;SHIROTA Tatsuo, 22nd International Conference on Oral and Maxillofacial Surgery 2015, 30 Oct. 2015, Melbourne
  • Tumor Protein D52 and D54 have Opposite Effects on Terminal Differentiation of Chondrocytes, ITO Chihiro;MUKUDAI Yoshiki;KATO Kosuke;MOTOHASHI Hiromi;KONDO Seiji;SHIROTA Tatsuo, 22nd International Conference on Oral and Maxillofacial Surgery 2015, 30 Oct. 2015, Melbourne
  • The Opposite Effects between Tumor Protein D52 and D54 on Anchorage-independent Proliferation of Squamous Cell Carcinoma Cells, KATO Kosuke;MUKUDAI Yoshiki;MOTOHASHI Hiromi;ITO Chihiro;KONDO Seiji;SHIROTA Tatsuo, 22nd International Conference on Oral and Maxillofacial Surgery 2015, 30 Oct. 2015, Melbourne
  • Tumor protein D52 and D54 have opposite effects on terminal differentiation of chondrocytes, 伊藤　千洋;椋代　義樹;加藤　光佑;本橋　宏美;近藤　誠二;代田　達夫, 第60回日本口腔外科学会総会・学術大会, 16 Oct. 2015, 名古屋
  • The opposite effects between tumor protein D52 and D54 on anchorage-independent proliferation of squamous cell carcinoma cells., 加藤　光佑;椋代　義樹;本橋　宏美;伊藤　千洋;近藤　誠二;代田　達夫, 第60回日本口腔外科学会総会・学術大会, 16 Oct. 2015, 名古屋
  • TPD52 family mRNA is post-transcriptional regulation on its gene expression, 本橋　宏美;加藤　光佑;伊藤　千洋;椋代　義樹;近藤　誠二;代田　達夫, 第60回日本口腔外科学会総会・学術大会, 16 Oct. 2015, 名古屋
  • Effects of the extracts of Paeonia lutea on proliferation and metasta sis of squamous cell carcinoma, 椋代　義樹;本橋　宏美, 第57回歯科基礎医学会学術大会, 13 Sep. 2015, 新潟
  • TPD52ファミリータンパクの遺伝子発現制御の検索, 本橋　宏美;椋代　義樹, 第57回歯科基礎医学会学術大会, 12 Sep. 2015, 新潟
  • 口腔扁平上皮癌細胞の増殖・浸潤・転移に対するTPD52ファミリーの相互作用の検索, 加藤　光佑;椋代　義樹;本橋　宏美;伊藤　千洋;近藤　誠二;代田　達夫, 第69回日本口腔科学会学術集会, 15 May 2015, 大阪
  • TPD52ファミリー遺伝子発現は転写後制御を受ける, 本橋　宏美;椋代　義樹;伊藤　千洋;加藤　光佑;近藤　誠二;代田　達夫, 第69回日本口腔科学会学術集会, 15 May 2015, 大阪
  • 内軟骨性骨化、膜性骨化におけるTPD52ファミリーの役割の検索, 伊藤　千洋;椋代　義樹;加藤　光佑;本橋　宏美;近藤　誠二;代田　達夫, 第69回日本口腔科学会学術集会, 14 May 2015, 大阪
  • The expression of TPD family genes undergo post-transcriptional regulation, 椋代　義樹;本橋　宏美;伊藤　千洋;加藤　光佑;近藤　誠二;代田　達夫, 第37回日本分子生物学会年会, 25 Nov. 2014, 横浜

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