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Yamada Atsushi

■FacultyOral Biochemistry
■PositionAssociate Professor
Last Updated :2025/04/01

Researcher

基本情報

Profile and Settings

  • 氏名

    Yamada Atsushi

Affiliation

  • Oral Biochemistry, Associate Professor

Location

  • Hatanodai Campus

Degree

  • Doctor of Veterinary Medical Science, The University of Tokyo, Mar. 2001

Research Areas

  • Life Science, Oral biological science

Achievements

Published Papers

  • Lactate-induced histone lactylation by p300 promotes osteoblast differentiation., Minami Erika;Sasa Kiyohito;Yamada Atsushi;Kawai Ryota;Yoshida Hiroshi;Nakano Haruhisa;Maki Koutaro;Kamijo Ryutaro, PloS one, 18(12), Dec. 2023, Peer-reviewed
  • BMP-2-mediated signaling suppresses salivary gland development., Shinnosuke Ono; Atsushi Yamada; Junichi Tanaka; Akane Yukimori; Kiyohito Sasa; Kenji Mishima; Takahiro Funatsu; Ryutaro Kamijo, Biochemical and biophysical research communications, 681:1 - 6, Sep. 2023, Peer-reviewed
  • Kielin/chordin-like protein enhances induction of osteoblast differentiation by Bone Morphogenetic Protein-2., Kei Nagasaki; Atsushi Yamada; Kiyohito Sasa; Ryutaro Kamijo, FEBS open bio, May 2023, Peer-reviewed
  • Low oxygen tension suppresses the death of chondrocyte-like ATDC5 cells induced by interleukin-1ß, Motohiro Tanaka; Yoichi Miyamoto; Kiyohito Sasa; Kentaro Yoshimura; Atsushi Yamada; Tatsuo Shirota; Ryutaro Kamijo, In Vitro Cellular & Developmental Biology - Animal, Aug. 2022, Peer-reviewed
  • Extracellular acidification augments sclerostin and osteoprotegerin production by Ocy454 mouse osteocytes, Kaori Ikezaki-Amada; Yoichi Miyamoto; Kiyohito Sasa; Atsushi Yamada; Mitsuhiro Kinoshita; Kentaro Yoshimura; Ryota Kawai; Fumiko Yano; Tatsuo Shirota; Ryutaro Kamijo, Biochemical and Biophysical Research Communications, 597:44 - 51, Mar. 2022, Peer-reviewed
  • Establishment of Down's syndrome periodontal ligament cells by transfection with SV40T-Ag and hTERT., Takeyoshi Asakawa; Atsushi Yamada; Masumi Kugino; Tomokazu Hasegawa; Kentaro Yoshimura; Kiyohito Sasa; Mitsuhiro Kinoshita; Masakazu Nitta; Karin Nagata; Tomomi Sugiyama; Ryutaro Kamijo; Takahiro Funatsu, Human cell, 35(1):379 - 383, Sep. 2021, Peer-reviewed
  • Protein Kinase C Alpha Acting Through Phorbol-12-Myristate 13-Acetate Regulates Nephronectin Gene Expression Via c-Jun and c-Fos Transcription Factors, Mitsuhiro Kinoshita; Atsushi Yamada; Kiyohito Sasa; Kaori Ikezaki; Tatsuo Shirota; Ryutaro Kamijo, Scientific reports, 11(1):20360 - 20360, Jun. 2021, Peer-reviewed
  • Cdc42 has important roles in postnatal angiogenesis and vasculature formation., Yuko Yoshida; Atsushi Yamada; Yoshihiro Akimoto; Kyoko Abe; Sachie Matsubara; Junri Hayakawa; Junichi Tanaka; Mitsuhiro Kinoshita; Tadashi Kato; Hiroaki Ogata; Akiko Sakashita; Kenji Mishima; Yoshiaki Kubota; Hayato Kawakami; Ryutaro Kamijo; Takehiko Iijima, Developmental biology, 477:64 - 69, May 2021, Peer-reviewed
  • Zoledronate promotes inflammatory cytokine expression in human CD14-positive monocytes among peripheral mononuclear cells in presence of γδ T cells., Reiko Takimoto; Tetsuo Suzawa; Atsushi Yamada; Kiyohito Sasa; Yoichi Miyamoto; Kentaro Yoshimura; Yuji Sasama; Motohiro Tanaka; Mitsuhiro Kinoshita; Kaori Ikezaki; Makoto Ichikawa; Matsuo Yamamoto; Tatsuo Shirota; Ryutaro Kamijo, Immunology, 162(3):306 - 313, Nov. 2020, Peer-reviewed
  • Osteoblastic differentiation of bone marrow mesenchymal stem cells in uremic rats., KATO Tadashi;MIZOBUCHI Masahide;SASA Kiyohito;YAMADA Atsushi;OGATA Hiroaki;HONDA Hirokazu;SAKASHITA Akiko;KAMIJO Ryutaro, Biochem Biophys Res Commun, 532(1):11 - 18, Oct. 2020, Peer-reviewed
  • Lipopolysaccharide (LPS) inhibits ectopic bone formation induced by bone morphogenetic protein-2 and TGF-β1 through IL-1β production., MATSUMOTO Akifumi;TAKAMI Masamichi;URANO Eri;NAKAMACHI Tomoya;YOSHIMURA Kentaro;YAMADA Atsushi;SUZAWA Tetsuo;MIYAMOTO Yoichi;BABA Kazuyoshi;KAMIJO Ryutaro, J Oral Biosci., 62(1):44 - 51, Mar. 2020, Peer-reviewed
  • Functional Analysis of PTH1R Variants Found in Primary Failure of Eruption., E Izumida; T Suzawa; Y Miyamoto; A Yamada; M Otsu; T Saito; T Yamaguchi; K Nishimura; M Ohtaka; M Nakanishi; K Yoshimura; K Sasa; R Takimoto; R Uyama; T Shirota; K Maki; R Kamijo, Journal of dental research, 99(4):22034520901731 - 22034520901731, Jan. 2020, Peer-reviewed
  • Visualization of junctional epithelial cell replacement by oral gingival epithelial cells over a life time and after gingivectomy, KATO Mayu;TANAKA Junichi;AIZAWA Ryo;YAJIMA-HIMURO Sara;SEKI Tatsuaki;TANAKA Keisuke;YAMADA Atsushi;OGAWA Miho;KAMIJO Ryutaro;TSUJI Takashi;MISHIMA Kenji;YAMAMOTO Matsuo, Sci Rep, 9(1):7640, May 2019, Peer-reviewed
  • Cdc42 regulates cranial suture morphogenesis and ossification., AIZAWA Ryo;YAMADA Atsushi;SEKI Tatsuaki;TANAKA Junichi;NAGAHAMA Ryo;IKEHATA Mikiko;KATO Tadashi;SAKASHITA Akiko;OGATA Hiroaki;CHIKAZU Daichi;MAKI Koutaro;MISHIMA Kenji;YAMAMOTO Matsuo;KAMIJO Ryutaro, Biochem Biophys Res Commun, 512(2):145 - 149, Apr. 2019, Peer-reviewed
  • Nephronectin Expression is Inhibited by Inorganic Phosphate in Osteoblasts., Tadashi Kato; Atsushi Yamada; Kiyohito Sasa; Kentaro Yoshimura; Naoko Morimura; Hiroaki Ogata; Akiko Sakashita; Ryutaro Kamijo, Calcified tissue international, 104(2):201 - 206, Feb. 2019, Peer-reviewed
  • Monocarboxylate transporter-1 promotes osteoblast differentiation via suppression of p53, a negative regulator of osteoblast differentiation., SASA Kiyohito;YOSHIMURA Kentaro;YAMADA Atsushi;SUZUKI Dai;MIYAMOTO Yoichi;IMAI Hiroko;NAGAYAMA Kazuhiro;MAKI Koutaro;YAMAMOTO Matsuo;KAMIJO Ryutaro, Sci Rep, 8(1):10579, Jul. 2018, Peer-reviewed
  • Cooperation of Rho family proteins Rac1 and Cdc42 in cartilage development and calcified tissue formation, IKEHATA Mikiko;YAMADA Atsushi;FUJITA Koji;YOSHIDA Yuko;KATO Tadashi;SAKASHITA Akiko;OGATA Hiroaki;IIJIMA Takehiko;KURODA Masahiko;CHIKAZU Daichi;KAMIJO Ryutaro, Biochem Biophys Res Commun, 500(3):525 - 529, Jun. 2018, Peer-reviewed
  • FGF-2 suppresses expression of nephronectin via JNK and PI3K pathways, KATO Tadashi;YAMADA Atsushi;IKEHATA Mikiko;YOSHIDA Yuko;SASA Kiyohito;MORIMURA Naoko;SAKASHITA Akiko;IIJIMA Takehiko;CHIKAZU Daichi;OGATA Hiroaki;KAMIJO Ryutaro, FEBS Open Bio, 8(5):836 - 842, May 2018, Peer-reviewed
  • IL-1β suppresses nephronectin expression in osteoblasts via ERK1/2 and JNK, IEZUMI Yuka;YAMADA Atsushi;MINAMI Erika;IKEHATA Mikiko;YOSHIDA Yuko;KATO Tadashi ;MORIMURA Naoko;OGATA Hiroaki;SAKASHITA Akiko;IIJIMA Takehiko;CHIKAZU Daichi;KAMIJO Ryutaro, Biochem Biophys Res Commun, 493(1):773 - 775, Nov. 2017, Peer-reviewed
  • Wnt/ß-catenin signaling activates nephronectin expression in osteoblasts., IKEHATA Mikiko;YAMADA Atsushi;MORIMURA Naoko;ITOSE Masakatsu;SUZAWA Tetsuo;SHIROTA Tatsuo;CHIKAZU Daichi ;KAMIJO Ryutaro, Biochem Biophys Res Commun, 484(2):231 - 234, Mar. 2017, Peer-reviewed
  • Comprehensive genetic exploration of selective tooth agenesis of mandibular incisors by exome sequencing., Tetsutaro Yamaguchi; Kazuyoshi Hosomichi; Keisuke Yano; Yong-Il Kim; Hirofumi Nakaoka; Ryosuke Kimura; Hirotada Otsuka; Naoko Nonaka; Shugo Haga; Masahiro Takahashi; Tatsuo Shirota; Yoshiaki Kikkawa; Atsushi Yamada; Ryutaro Kamijo; Soo-Byung Park; Masanori Nakamura; Koutaro Maki; Ituro Inoue, Human genome variation, 4:17005 - 17005, 2017, Peer-reviewed
  • Cdc42 is crucial for facial and palatal formation during craniofacial development., OSHIMA-NAKAYAMA Mutsuko;YAMADA Atsushi;KUROSAWA Tamaki;AIZAWA Ryo;SUZUKI Dai;SAITO Yoshiro;KASSAI Hidetoshi;SATO Yuki;YAMAMOTO Matsuo;SHIROTA Tatsuo;AIBA Atsu;MAKI Koutaro;KAMIJO Ryutaro, Bone Rep, 5:1 - 6, Dec. 2016, Peer-reviewed
  • Expression of nephronectin is enhanced by 1 alpha,25-dihydroxyvitamin D-3, Katsuhiro Hiranuma; Atsushi Yamada; Tamaki Kurosawa; Ryo Aizawa; Dai Suzuki; Yoshiro Saito; Ryo Nagahama; Mikiko Ikehata; Masayuki Tsukasaki; Naoko Morimura; Daichi Chikazu; Koutaro Maki; Tatsuo Shirota; Masamichi Takami; Matsuo Yamamoto; Takehiko Iijima; Ryutaro Kamijo, FEBS OPEN BIO, 6(9):914 - 918, Sep. 2016, Peer-reviewed
  • Nephronectin expression is up-regulated by BMP-2., KUROSAWA Tamaki;YAMADA Atsushi;SUZUKI Dai;MORIMURA Naoko;SASAGANE Yoshiyuki;ITABE Hiroyuki;KAMIJO Ryutaro, Biol Pharm Bull, 39(7):1211 - 1215, Jul. 2016, Peer-reviewed
  • Continuous monitoring of caspase-3 activation induced by propofol in developing mouse brain., KONNO Ayumi;NISHIMURA Akiko;NAKAMURA Shiro;MOCHIZUKI Ayako;YAMADA Atsushi;KAMIJO Ryutaro;INOUE Tomio;IIJIMA Takehiko, Int J Dev Neurosci, 51:42 - 49, Jun. 2016, Peer-reviewed
  • Rho GTPase protein Cdc42 is critical for postnatal cartilage development., NAGAHAMA Ryo;YAMADA Atsushi;TANAKA Junichi;AIZAWA Ryo;SUZUKI Dai;KASSAI Hidetoshi;YAMAMOTO Matsuo;MISHIMA Kenji;AIBA Atsu;MAKI Koutaro;KAMIJO Ryutaro, Biochem Biophys Res Commun, 470(4):813 - 817, Feb. 2016, Peer-reviewed
  • Nephronectin: an extracellular matrix protein with diverse functions, YAMADA Atsushi;KAMIJO Ryutaro, J Dent Oral Disord, 2(1):1004, Jan. 2016, Peer-reviewed
  • Localization and osteoblastic differentiation potential of neural crest-derived cells in oral tissues of adult mice., ONO Miki;SUZAWA Tetsuo;TAKAMI Masamichi;YAMAMOTO Gou;HOSONO Tomohiko;YAMADA Atsushi;SUZUKI Dai;YOSHIMURA Kentaro;WATAHIKI Junichi;HAYASHI Ryuhei;ARATA Satoru;MISHIMA Kenji;NISHIDA Kohji;OSUMI Noriko;MAKI Koutaro;KAMIJO Ryutaro, Biochem Biophys Res Commun, 464(4):1209 - 1214, Sep. 2015, Peer-reviewed
  • Association of aging with gene expression profiling in mouse submandibular glands, Yoshiro Saito; Atsushi Yamada; Dai Suzuki; Junichi Tanaka; Ryo Nagahama; Tamaki Kurosawa; Koutaro Maki; Kenji Mishima; Tatsuo Shirota; Ryutaro Kamijo, Genomics Data, 5:115 - 119, Sep. 2015, Peer-reviewed
  • New iron preparations for CKD patients, 緒方　浩顕;加藤　憲, 腎と透析, 79(1):121 - 127, Jul. 2015
  • Enhanced in vitro biological activity generated by surface characteristics of anodically oxidized titanium--the contribution of the oxidation effect, WU Rihan;YAMADA Atsushi;SUZUKI Dai;SHIBATA Yo;KAMIJO Ryutaro;MIYAZAKI Takashi, Eur Cell Mater, 29:290 - 302, May 2015, Peer-reviewed
  • Expression of Nephronectin is inhibited by Oncostatin M via both JAK/STAT and MAPK pathways., KUROSAWA Tamaki;YAMADA Atsushi;TAKAMI Masamichi;SUZUKI Dai;SAITO Yoshiro;HIRANUMA Katsuhiro;ENOMOTO Takuya;MORIMURA Naoko;YAMAMOTO Matsuo;IIJIMA Takehiko;SHIROTA Tatsuo;ITABE Hiroyuki;KAMIJO Ryutaro, FEBS Open Bio, 5:303 - 307, Apr. 2015, Peer-reviewed
  • Bone micro-fragility caused by the mimetic aging processes in α-klotho deficient mice: in situ nanoindentation assessment of dilatational bands, MARUYAMA Noriko;SHIBATA Yo;MOCHIZUKI Ayako;YAMADA Atsushi;MAKI Koutaro;INOUE Tomio;KAMIJO Ryutaro;MIYAZAKI Takashi, Biomaterials, 47:62 - 71, Apr. 2015, Peer-reviewed, DOI:10.1016/j.biomaterials.2015.01.004
  • Cdc42 is critical for cartilage development during endochondral ossification., SUZUKI Wataru;YAMADA Atsushi;AIZAWA Ryo;SUZUKI Dai;KASSAI Hidetoshi;HARADA Takeshi;Nakayama Mutsuko;NAGAHAMA Ryo;MAKI Koutaro;TAKEDA Shu;YAMAMOTO Matsuo;AIBA Atsu;BABA Kazuyoshi;KAMIJO Ryutaro, Endocrinology, 156(1):314 - 322, Jan. 2015, Peer-reviewed, DOI:10.1210/en.2014-1032
  • Enhanced in vitro biological activity generated by surface characteristics of anodically oxidized titanium – the contribution of the oxidation effect, Wurihan; A. Yamada; D. Suzuki; Y. Shibata; R. Kamijo; T. Miyazaki, European Cells and Materials, 29:290 - 302, Jan. 2015, Peer-reviewed
  • Expression of nephronectin is inhibited by oncostatin M via both JAK/STAT and MAPK pathways, Tamaki Kurosawa; Atsushi Yamada; Masamichi Takami; Dai Suzuki; Yoshiro Saito; Katsuhiro Hiranuma; Takuya Enomoto; Naoko Morimura; Matsuo Yamamoto; Takehiko Iijima; Tatsuo Shirota; Hiroyuki Itabe; Ryutaro Kamijo, FEBS OPEN BIO, 5:303 - 307, 2015, Peer-reviewed
  • Strain-rate stiffening of cortical bone: observations and implications from nanoindentation experiments, MARUYAMA Noriko;SHIBATA Yo;WURIHAN;SWAIN Michael V;KATAOKA Yu;TAKIGUCHI Yuichi;YAMADA Atsushi;MAKI Koutaro; MIYAZAKI Takashi, Nanoscale, 6(24):14863 - 14871, Dec. 2014, Peer-reviewed, DOI:10.1039/c4nr03180f
  • Porphyromonas gingivalis-derived lysine gingipain enhances osteoclast differentiation induced by tumor necrosis factor-α and interleukin-1β but suppresses that by interleukin-17A: importance of proteolytic degradation of osteoprotegerin by lysine gingipain., AKIYAMA Tomohito;MIYAMOTO Yoichi;YOSHIMURA Kentaro;YAMADA Atsushi;TAKAMI Masamichi;SUZAWA Tetsuo;HOSHINO Marie;IMAMURA Takahisa;AKIYAMA Chie;YASUHARA Rika;MISHIMA Kenji;MARUYAMA Toshifumi;KOHDA Chikara;TANAKA Kazuo;POTEMPA Jan;YASUDA Hisataka;BABA Kazuyoshi;KAMIJO Ryutaro, J Biol Chem, 289(22):15621 - 15630, May 2014, Peer-reviewed, DOI:10.1074/jbc.M113.520510
  • Identification of gene expression profile of neural crest-derived cells isolated from submandibular glands of adult mice, TAKAHASHI Masahiro;SUZAWA Tetsuo;YAMADA Atsushi;YAMAGUCHI Tetsutaro;MISHIMA Kenji;OSUMI Noriko;MAKI Koutaro;KAMIJO Ryutaro, Biochem Biophys Res Commun, 446(2):481 - 486, Apr. 2014, Peer-reviewed, DOI:10.1016/j.bbrc.2014.02.130
  • Rho family small G proteins: lessons from tissue-specific gene knockout studies., YAMADA Atsushi;AIBA Atsu;KAMIJO Ryutaro, J Oral Biosci, 56(1):23 - 29, Feb. 2014, Peer-reviewed
  • Strain-rate stiffening of cortical bone: observations and implications from nanoindentation experiments, Noriko Maruyama; Yo Shibata; Wurihan; Michael V. Swain; Yu Kataoka; Yuichi Takiguchi; Atsushi Yamada; Koutaro Maki; Takashi Miyazaki, NANOSCALE, 6(24):14863 - 14871, 2014, Peer-reviewed
  • Lysyl oxidase like-2 reinforces unsatisfactory ossification induced by bone morphogenetic protein-2., SHIBATA Yo;SUZUKI Dai;WU Rihan;YAMADA Atsushi;MARUYAMA Noriko;FUJISAWA Naoki;KAMIJO Ryutaro;MIYAZAKI Takashi, Nanomedicine, 9(7):1036 - 1047, Oct. 2013, Peer-reviewed, DOI:10.1016/j.nano.2013.04.008
  • BMP-2 Induced Expression of Alx3 That Is a Positive Regulator of Osteoblast Differentiation, Takashi Matsumoto; Atsushi Yamada; Ryo Aizawa; Dai Suzuki; Masayuki Tsukasaki; Wataru Suzuki; Mutsuko Nakayama; Koutaro Maki; Matsuo Yamamoto; Kazuyoshi Baba; Ryutaro Kamijo, PLOS ONE, 8(6):e68774, Jun. 2013, Peer-reviewed
  • Octacalcium phosphate suppresses chondrogenic differentiation of ATDC5 cells., SHIBUYA Isao;YOSHIMURA Kentaro;MIYAMOTO Yoichi;YAMADA Atsushi;TAKAMI Masamichi;SUZAWA Tetsuo;SUZUKI Dai;IKUMI Noriharu;HIURA Fumitaka;ANADA Takahisa;SUZUKI Osamu;KAMIJO Ryutaro, Cell Tissue Res, 352(2):401 - 412, May 2013, Peer-reviewed
  • Downregulation of Carbonic Anhydrase IX Promotes Col10a1 Expression in Chondrocytes, Toshifumi Maruyama; Yoichi Miyamoto; Gou Yamamoto; Atsushi Yamada; Kentaro Yoshimura; Tetsuo Suzawa; Masamichi Takami; Tomohito Akiyama; Marie Hoshino; Fuminori Iwasa; Noriharu Ikumi; Tetsuhiko Tachikawa; Kenji Mishima; Kazuyoshi Baba; Ryutaro Kamijo, PLoS ONE, 8(2):e56984, Feb. 2013, Peer-reviewed
  • Expression of myelin and lymphocyte protein (MAL) in oral carcinogenesis, Samir Kumar Pal; Sunaki Noguchi; Gou Yamamoto; Atsushi Yamada; Tomohide Isobe; Shigeo Hayashi; Jun-Ichi Tanaka; Yoichi Tanaka; Ryutaro Kamijo; Gen-Yuki Yamane; Tetsuhiko Tachikawa, MEDICAL MOLECULAR MORPHOLOGY, 45(4):222 - 228, Dec. 2012, Peer-reviewed
  • Nephronectin expression is regulated by SMAD signaling in osteoblast-like MC3T3-E1 cells, Masayuki Tsukasaki; Atsushi Yamada; Kentaro Yoshimura; Agasa Miyazono; Matsuo Yamamoto; Masamichi Takami; Yoichi Miyamoto; Naoko Morimura; Ryutaro Kamijo, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 425(2):390 - 392, Aug. 2012, Peer-reviewed
  • BMP2 Differentially Regulates the Expression of Gremlin1 and Gremlin2, the Negative Regulators of BMP Function, During Osteoblast Differentiation, Dai Suzuki; Atsushi Yamada; Ryo Aizawa; Sakie Funato; Takashi Matsumoto; Wataru Suzuki; Masamichi Takami; Yoichi Miyamoto; Tetsuo Suzawa; Matsuo Yamamoto; Kazuyoshi Baba; Ryutaro Kamijo, CALCIFIED TISSUE INTERNATIONAL, 91(1):88 - 96, Jul. 2012, Peer-reviewed
  • Cdc42 is required for chondrogenesis and interdigital programmed cell death during limb development, Ryo Aizawa; Atsushi Yamada; Dai Suzuki; Tadahiro Iimura; Hidetoshi Kassai; Takeshi Harada; Masayuki Tsukasaki; Gou Yamamoto; Tetsuhiko Tachikawa; Kazuki Nakao; Matsuo Yamamoto; Akira Yamaguchi; Atsu Aiba; Ryutaro Kamijo, MECHANISMS OF DEVELOPMENT, 129(1-4):38 - 50, Mar. 2012, Peer-reviewed
  • Expression of POEM, a positive regulator of osteoblast differentiation, is suppressed by TNF-alpha, Masayuki Tsukasaki; Atsushi Yamada; Dai Suzuki; Ryo Aizawa; Agasa Miyazono; Yoichi Miyamoto; Tetsuo Suzawa; Masamichi Takami; Kentaro Yoshimura; Naoko Morimura; Matsuo Yamamoto; Ryutaro Kamijo, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 410(4):766 - 770, Jul. 2011, Peer-reviewed
  • Experience Dictates Stem Cell Fate in the Adult Hippocampus, Alex Dranovsky; Alyssa M. Picchini; Tiffany Moadel; Alexander C. Sisti; Atsushi Yamada; Shioko Kimura; E. David Leonardo; Rene Hen, NEURON, 70(5):908 - 923, Jun. 2011, Peer-reviewed
  • Monocarboxylate Transporter-1 Is Required for Cell Death in Mouse Chondrocytic ATDC5 Cells Exposed to Interleukin-1 beta via Late Phase Activation of Nuclear Factor kappa B and Expression of Phagocyte-type NADPH Oxidase, Kentaro Yoshimura; Yoichi Miyamoto; Rika Yasuhara; Toshifumi Maruyama; Tomohito Akiyama; Atsushi Yamada; Masamichi Takami; Tetsuo Suzawa; Shoko Tsunawaki; Tetsuhiko Tachikawa; Kazuyoshi Baba; Ryutaro Kamijo, JOURNAL OF BIOLOGICAL CHEMISTRY, 286(17):14744 - 14752, Apr. 2011, Peer-reviewed
  • Bone morphogenetic protein 2 enhances mouse osteoclast differentiation via increased levels of receptor activator of NF-kappa B ligand expression in osteoblasts, Keita Tachi; Masamichi Takami; Baohong Zhao; Ayako Mochizuki; Atsushi Yamada; Yoichi Miyamoto; Tomio Inoue; Kazuyoshi Baba; Ryutaro Kamijo, CELL AND TISSUE RESEARCH, 342(2):213 - 220, Nov. 2010, Peer-reviewed
  • Osteoclast Differentiation Induced by Synthetic Octacalcium Phosphate Through Receptor Activator of NF-kappa B Ligand Expression in Osteoblasts, Masamichi Takami; Ayako Mochizuki; Atsushi Yamada; Keita Tachi; Baohong Zhao; Yoichi Miyamoto; Takahisa Anada; Yoshitomo Honda; Tomio Inoue; Masanori Nakamura; Osamu Suzuki; Ryutaro Kamijo, TISSUE ENGINEERING PART A, 15(12):3991 - 4000, Dec. 2009, Peer-reviewed
  • Essential mesenchymal role of small GTPase Rac1 in interdigital programmed cell death during limb development., Suzuki D; Yamada A; Amano T; Yasuhara R; Kimura A; Sakahara M; Tsumaki N; Takeda S; Tamura M; Nakamura M; Wada N; Nohno T; Shiroishi T; Aiba A; Kamijo R, Dev Biol., 335(2):396 - 406, Nov. 2009, Peer-reviewed
  • Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis, Baohong Zhao; Masamichi Takami; Atsushi Yamada; Xiaogu Wang; Takako Koga; Xiaoyu Hu; Tomohiko Tamura; Keiko Ozato; Yongwon Choi; Lionel B. Ivashkiv; Hiroshi Takayanagi; Ryutaro Kamijo, NATURE MEDICINE, 15(9):1066 - U121, Sep. 2009, Peer-reviewed
  • Oncostatin M Regulates Secretoglobin 3A1 and 3A2 Expression in a Bidirectional Manner, Takeshi Tomita; Atsushi Yamada; Masaaki Miyakoshi; Taketomo Kido; Faruk Sheikh; Achara Srisodsai; Atsushi Miyajima; Raymond P. Donnelly; Shioko Kimura, AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 40(5):620 - 630, May 2009, Peer-reviewed
  • IFN-gamma down-regulates Secretoglobin 3A1 gene expression, Atsushi Yamada; Dai Suzuki; Agasa Miyazono; Kumiko Oshima; Akihide Kamiya; Baohong Zhao; Masamichi Takami; Raymond P. Donnelly; Hiroyuki Itabe; Matsuo Yamamoto; Shioko Kimura; Ryutaro Kamijo, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 379(4):964 - 968, Feb. 2009, Peer-reviewed
  • Characterization of synovial cell clones isolated from rheumatoid arthritis patients: Possible involvement of TNF-alpha in reduction of osteoprotegerin in synovium, Baohong Zhao; Masamichi Takami; Yoichi Miyamoto; Tetsuo Suzawa; Atsushi Yamada; Ayako Mochizuki; Rika Yasuhara; Xiaogu Wang; Tomio Inoue; Osamu Namiki; Keizo Sakamoto; Ryutaro Kamijo, CYTOKINE, 41(1):61 - 70, Jan. 2008, Peer-reviewed
  • TGF-beta suppresses POEM expression through ERK1/2 and JNK in osteoblasts, Agasa Miyazono; Atsushi Yamada; Naoko Morimura; Masamichi Takami; Dai Suzuki; Makoto Kobayashi; Ken-ichi Tezuka; Matsuo Yamamoto; Ryutaro Kamijo, FEBS LETTERS, 581(27):5321 - 5326, Nov. 2007, Peer-reviewed
  • Interleukin-4 inhibition of osteoclast differentiation is stronger than that of interleukin-13 and they are equivalent for induction of osteoprotegerin production from osteoblasts, Atsushi Yamada; Masamichi Takami; Tadaharu Kawawa; Rika Yasuhara; Baohong Zhao; Ayako Mochizuki; Yoichi Miyamoto; Tomoo Eto; Hisataka Yasuda; Yuko Nakamichi; Nacksung Kim; Takenobu Katagiri; Tatsuo Suda; Ryutaro Kamijo, IMMUNOLOGY, 120(4):573 - 579, Apr. 2007, Peer-reviewed
  • Nitric oxide in pulp cell growth, differentiation, and mineralization., Yasuhara R; Suzawa T; Miyamoto Y; Wang X; Takami M; Yamada A; Kamijo R, J Dent Res., 86(2):163 - 168, 2007, Peer-reviewed
  • Peroxisome proliferator-activated receptor alpha activation during pregnancy severely impairs mammary lobuloalveolar development in mice, Qian Yang; Reiko Kurotani; Atsushi Yamada; Shioko Kimura; Frank J. Gonzalez, ENDOCRINOLOGY, 147(10):4772 - 4780, Oct. 2006, Peer-reviewed
  • Alterations in skin and stratified epithelia by constitutively activated PPAR alpha, Qian Yang; Atsushi Yamada; Shioko Kimura; Jeffrey M. Peters; Frank J. Gonzalez, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 126(2):374 - 385, Feb. 2006, Peer-reviewed
  • Induction of uteroglobin-related protein 2 (Ugrp2) gene expression by the Th2 cytokines IL-4 and IL-13, A Yamada; F Sheikh; T Niimi; FJ DeMayo; AD Keegan; RP Donnelly; S Kimura, JOURNAL OF IMMUNOLOGY, 175(9):5708 - 5715, Nov. 2005, Peer-reviewed
  • Induction of uteroglobin-related protein 2 (Ugrp2) expression by EGF and TGF alpha, A Yamada; S Kimura, FEBS LETTERS, 579(10):2221 - 2225, Apr. 2005, Peer-reviewed
  • Microarray analysis using amplified mRNA from laser capture microdissection of microscopic hepatocellular precancerous lesions and frozen hepatocellular carcinomas reveals unique and consistent gene expression profiles, SH Yim; JM Ward; Y Dragan; A Yamada; PC Scacheri; S Kimura; FJ Gonzalez, TOXICOLOGIC PATHOLOGY, 31(3):295 - 303, May 2003, Peer-reviewed
  • FD-891, a structural analogue of concanamycin A that does not affect vacuolar acidification or perforin activity, yet potently prevents cytotoxic T lymphocyte-mediated cytotoxicity through the blockage of conjugate formation., T Kataoka; A Yamada; M Bando; T Honma; K Mizoue; K Nagai, Immunology, 100(2):170 - 7, Jun. 2000, Peer-reviewed
  • Regulation of long-term potentiation by H-Ras through NMDA receptor phosphorylation., T Manabe; A Aiba; A Yamada; T Ichise; H Sakagami; H Kondo; M Katsuki, The Journal of neuroscience : the official journal of the Society for Neuroscience, 20(7):2504 - 11, Apr. 2000, Peer-reviewed
  • The fungal metabolite gliotoxin: immunosuppressive activity on CTL-mediated cytotoxicity., A Yamada; T Kataoka; K Nagai, Immunology letters, 71(1):27 - 32, Jan. 2000, Peer-reviewed
  • Guaianolides as immunomodulators. Synthesis and biological activities of dehydrocostus lactone, mokko lactone, eremanthin, and their derivatives., S Yuuya; H Hagiwara; T Suzuki; M Ando; A Yamada; K Suda; T Kataoka; K Nagai, Journal of natural products, 62(1):22 - 30, Jan. 1999, Peer-reviewed
  • Immunosuppressive effects of gallic acid and chebulagic acid on CTL-mediated cytotoxicity., S Hamada; T Kataoka; J T Woo; A Yamada; T Yoshida; T Nishimura; N Otake; K Nagai, Biological & pharmaceutical bulletin, 20(9):1017 - 9, Sep. 1997, Peer-reviewed
  • Identification of low molecular weight probes on perforin- and Fas-based killing mediated by cytotoxic T lymphocytes., T Kataoka; M Taniguchi; A Yamada; H Suzuki; S Hamada; J Magae; K Nagai, Bioscience, biotechnology, and biochemistry, 60(10):1726 - 8, Oct. 1996, Peer-reviewed

Presentations

  • Nephronectin gene expression is suppressed by phorbol 12-myristate 13-acetate (PMA) via PKC signaling pathway., 木下　三博;山田　篤;上條　竜太郎, 第63回歯科基礎医学会学術大会, 11 Oct. 2021, オンライン開催
  • 骨芽細胞においてPMAはNephronectinの発現をPKCαおよびδを介し抑制する, 木下　三博;山田　篤;北條　宏徳;大庭　伸介, 第38回日本骨代謝学会学術集会, 09 Oct. 2020, 神戸およびLIVE配信、オンデマンド配信
  • PMAによる細胞外マトリックスタンパク質Nephronectinの発現制御機構の解明, 木下　三博;山田　篤;上條　竜太郎, 第56回日本口腔組織培養学会学術大会・総会, 02 Nov. 2019, 岐阜
  • Zoledronate promoted the expression of inflammatory cytokines in CD14+ cells in human peripheral blood mononuclear cells and inhibited their differentiation into osteoclasts, TAKIMOTO Reiko;MIYAMOTO Yoichi;YAMADA Atsushi;SUZAWA Tetsuo;SASA Kiyohito;KAMIJO Ryutaro;SHIROTA Tatsuo, 第66回国際歯科研究学会日本部会総会・学術大会, 17 Nov. 2018, 札幌
  • Cdc42は出生後の血管形成および血管を介した骨形成に重要な役割を果たしている, 吉田　優子;山田　篤;池畑　美紀子;加藤　憲;上條　竜太郎, 第55回日本口腔組織培養学会学術大会・総会, 10 Nov. 2018, 西宮
  • Cdc42 is expected to become a target gene for the control of vascular permeability, YOSHIDA Yuko;YAMADA Atsushi;AKIMOTO Yoshihiro;ABE Kyoko;KAMIJO Ryutaro;IIJIMA Takehiko, Anesthesiology 2018 Annual Meeting, 16 Oct. 2018, San Francisco
  • Cdc42 plays important roles in postnatal angiogenesis and bone formation, YOSHIDA Yuko;YAMADA Atsushi;IIJIMA Takehiko;KAMIJO Ryutaro, The 28th annual scientific meeting of the Australian and New Zealand Bone and Mineral Society(ANZBMS), 04 Sep. 2018, Queenstown
  • Cdc42 plays pivotal roles in postnatal angiogenesis and bone formation, YOSHIDA Yuko;YAMADA Atsushi;IIJIMA Takehiko;KAMIJO Ryutaro, 15th Meeting of Bone Biology Forum, 17 Aug. 2018, Chiba
  • 骨軟骨形成におけるRhoファミリー低分子量Gタンパク質Rac1とCdc42の機能解析, 池畑　美紀子;山田　篤;吉田　優子;加藤　憲;近津　大地;上條　竜太郎, 第36回日本骨代謝学会学術集会, 27 Jul. 2018, 長崎
  • Cdc42は出生後の血管形成および血管を介した骨形成に重要な役割を果たしている, 吉田　優子;山田　篤;池畑　美紀子;加藤　憲;上條　竜太郎, 第36回日本骨代謝学会学術集会, 26 Jul. 2018, 長崎
  • Extracellular phosphate suppresses expression of Nephronectin via FGF signaling, 加藤　憲;山田　篤;吉田　優子;池畑　美紀子;緒方　浩顕;上條　竜太郎, 第36回日本骨代謝学会学術集会, 26 Jul. 2018, 長崎
  • α-cyano-4-hydroxycinnamic acid は破骨細胞の骨吸収を抑制する, 今井　裕子;吉村　健太郎;宮本　洋一;山田　篤;笹　清人;茶谷　昌宏;髙見　正道;山本　松男;上條　竜太郎, 第4回日本骨免疫学会, 25 Jun. 2018, 名護
  • FGF-2による細胞外マトリックスタンパク質Nephronectinの発現制御機構の解明, 加藤　憲;山田　篤;上條　竜太郎, 第54回日本口腔組織培養学会学術大会・総会, 04 Nov. 2017, 盛岡
  • Small GTPase Rac1 is a negative regulator in calvarial osteoblast differentiation and ossification, 鈴木　大;山田　篤;笹　清人;上條　竜太郎, 第59回歯科基礎医学会学術大会, 17 Sep. 2017, 松本
  • 細胞外マトリックスタンパク質Nephronectinの発現制御機構の解明, 池畑　美紀子;山田　篤;上條　竜太郎, 第18回運動器科学研究会, 01 Sep. 2017, 呉
  • Cdc42 is critical for cartilage development through PTH-mediated signaling., 長濱　諒;山田　篤;槇　宏太郎;上條　竜太郎, 第58回歯科基礎医学会学術大会, 25 Aug. 2016, 札幌
  • 低分子量Gタンパク質Rac1は軟骨形成に必須である, 鈴木　大;山田　篤;竹田　秀;FRANK Beier;稲垣　克記;上條　竜太郎, 東京骨関節・フォーラム(第16回), 30 Jul. 2016, 東京
  • Rho GTPase protein Cdc42 is critical for postnatal cartilage development, 長濱　諒;山田　篤;鈴木　大;槇　宏太郎;上條　竜太郎, 第34回日本骨代謝学会学術集会・第3回アジア太平洋骨代謝学会議　, 23 Jul. 2016, 大阪
  • Expression of nephronectin is induced by 1α,25-Dehydroxyvitamin D3, 平沼　克洋;山田　篤;鈴木　大;長濱　諒;髙見　正道;上條　竜太郎, 第34回日本骨代謝学会学術集会・第3回アジア太平洋骨代謝学会議, 21 Jul. 2016, 大阪
  • microRNAによる骨軟骨形成に関与する遺伝子発現制御の解析, 鈴木　大;宮本　洋一;山田　篤;須澤　徹夫;吉村　健太郎;宇山　理紗;山本　松男;上條　竜太郎, 昭和大学歯学部文部科学省私立大学戦略的研究基盤形成支援事業平成27年度シンポジウム, 12 Mar. 2016, 東京
  • Regulation of nephronectin gene expression by 1α, 25-Dyhydroxyvitamin D3, HIRANUMA Katsuhiro;YAMADA Atsushi;SUZUKI Dai;IIJIMA Takehiko;KAMIJO Ryutaro, 2015 cell biology ascb annual meeting, 16 Dec. 2015, San Diego
  • Missense mutations in parathyroid hormone 1 receptor found in patients having primary failure of tooth eruption cause decreased response to parathyroid hormone., IZUMIDA Eri;MIYAMOTO Yoichi;YAMADA Atsushi;SAITO Taku;OTSU Makoto;YAMAGUCHI Tetsutaro;MAKI Koutaro;KAMIJO Ryutaro, 2015 cell biology ascb annual meeting, 13 Dec. 2015, San Diego
  • Cdc42 is critical for cartilage development during endochondral ossification at postnatal stage, NAGAHAMA Ryo;YAMADA Atsushi;SUZUKI Dai;MAKI Koutaro;KAMIJO Ryutaro, 2015 cell biology ascb annual meeting, 13 Dec. 2015, San Diego
  • Nephronectinに対する活性型ビタミンD3の発現制御機構の解析, 平沼　克洋;山田　篤;鈴木　大;飯島　毅彦;上條　竜太郎, 第52回日本口腔組織培養学会学術大会・総会, 21 Nov. 2015, 徳島
  • Cdc42は生後成長期の軟骨形成に重要である, 長濱　諒;山田　篤;鈴木　大;槇　宏太郎;上條　竜太郎, 第52回日本口腔組織培養学会学術大会, 21 Nov. 2015, 徳島
  • Cdc42 in neural crest derived cells is essential for palatal development, OSHIMA Mutsuko;YAMADA Atsushi;MAKI Koutaro;KAMIJO Ryutaro;SUZUKI Dai, Australian and New Zealand Bone and Mineral Society Annual Scientific Meeting 2015, 01 Nov. 2015, Hobart
  • Cdc42 is critical for postnatal cartilage development, NAGAHAMA Ryo;YAMADA Atsushi;SUZUKI Dai;MAKI Koutaro;KAMIJO Ryutaro, 第63回国際歯科研究学会日本部会総会・学術大会, 30 Oct. 2015, 福岡
  • Expression of nephronection is regulated by 1A, 25-Dyhydroxyvitamin D3, HIRANUMA Katsuhiro;YAMADA Atsushi;IIJIMA Takehiko;KAMIJO Ryutaro, 第63回国際歯科研究学会日本部会総会・学術大会, 30 Oct. 2015, 福岡
  • 神経堤由来細胞に発現するRhoファミリー低分子量Gタンパク質Cdc42は口蓋形成に必須である, 大島　睦子;山田　篤;鈴木　大;槇　宏太郎;上條　竜太郎, 第57回歯科基礎医学会学術大会, 12 Sep. 2015, 新潟
  • 低分子量Gタンパク質Cdc42は口蓋形成において重要な遺伝子である, 大島　睦子;山田　篤;鈴木　大;槇　宏太郎;上條　竜太郎, 第33回日本骨代謝学会学術集会, 23 Jul. 2015, 東京
  • Rhoファミリー低分子量Gタンパク質Rac1およびCdc42の骨･軟骨形成における機能解析, 山田　篤;鈴木　大;上條　竜太郎, 第1回日本骨免疫学会, 01 Jul. 2015, 宮古島
  • Cdc42遺伝子の口蓋形成過程における機能解析, 大島　睦子;山田　篤;槇　宏太郎;上條　竜太郎, 第69回日本口腔科学会学術集会, 14 May 2015, 大阪
  • microRNAによる骨芽細胞•エナメル芽細胞分化誘導に基づく新たな再生医療への挑戦, 須澤　徹夫;宮本　洋一;山田　篤;鈴木　大;吉村　健太郎;宇山　理紗;山本　松男;上條　竜太郎, 昭和大学歯学部文部科学省私立大学戦略的研究基盤形成支援事業平成26年度シンポジウム, 28 Mar. 2015, 東京
  • マイクロアレイを用いた顎下腺の加齢に伴う遺伝子変化の解析, 斉藤　芳郎;山田　篤;KAMIJO Ryutaro;代田　達夫, 昭和大学歯学部文部科学省私立大学戦略的研究基盤形成支援事業平成26年度シンポジウム, 28 Mar. 2015, 東京
  • Oncostatin Mによるネフロネクチン発現制御機構の解明, 黒澤　珠希;山田　篤;高見　正道;鈴木　大;守村　直子;板部　洋之;上條　竜太郎, 日本薬学会第135年会, 28 Mar. 2015, 神戸
  • LIVE IMAGING OF APOPTOGENIC CHANGE INDUCED BY GENERAL ANESTHETIC NEUROTOXICITY IN DEVELOPING MOUSE, KONNO Ayumi;NISHIMURA Akiko;NAKAMURA Shiro;YAMADA Atsushi;KAMIJO Ryutaro;INOUE Tomio;IIJIMA Takehiko, IARS 2015 Annual Meeting and International Science Symposium, 22 Mar. 2015, Honolulu
  • Cdc42は口蓋形成過程において必須の遺伝子である, 中山　睦子;山田　篤;鈴木　大;槇　宏太郎;上條　竜太郎, 第51回口腔組織培養学会学術大会・総会, 15 Nov. 2014, 北九州
  • Cdc42は口蓋形成過程において必須の遺伝子である, 中山　睦子;山田　篤;佐藤　友紀;上條　竜太郎;槇　宏太郎, 第73回日本矯正歯科学会大会・第5回日韓ジョイントミーティング, 21 Oct. 2014, 千葉
  • Cdc42 is essential for cartilage development during endochondral ossification., SUZUKI Wataru;YAMADA Atsushi;AIZAWA Ryo;SUZUKI Dai;TAKEDA Shu;YAMAMOTO Matsuo;BABA Kazuyoshi;KAMIJO Ryutaro, ANZBMS 24th Annual Scientific Meeting, 07 Sep. 2014, Queenstown
  • Cdc42は軟骨分化とそれに続く軟骨内骨化に必須である, 鈴木　航;山田　篤;相澤　怜;鈴木　大;竹田　秀;山本　松男;馬場　一美;上條　竜太郎, 第32回日本骨代謝学会学術集会, 24 Jul. 2014, 大阪
  • Cdc42は口蓋形成において必須の遺伝子である, 中山　睦子;山田　篤;佐藤　友紀;上條　竜太郎;槇　宏太郎, 第38回日本口蓋裂学会総会・学術集会, 29 May 2014, 札幌
  • Rhoファミリー低分子量Gタンパク質Rac1およびCdc42の骨•軟骨形成における機能解析, 山田　篤, 第13回　松本ボーンフォーラム, 09 May 2014, 松本
  • 低分子量Gタンパク質Cdc42は軟骨分化とそれに引き続く軟骨内骨化に必須である, 鈴木　航;山田　篤;馬場　一美;上條　竜太郎, 第68回日本口腔科学会学術集会, 08 May 2014, 東京
  • 毛包内の神経堤由来細胞による象牙芽細胞分化誘導., 森澤　絵里;須澤　徹夫;宮内　知彦;髙見　正道;山田　篤;宮本　洋一;林　竜平;西田　幸二;大隅　典子;馬場　一美;上條　竜太郎, 第11回日本再生医療学会総会, 12 Jun. 2012, 横浜

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