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Okumo Takayuki

■FacultyPhysiology
■PositionSenior Lecturer
Last Updated :2025/06/13

Researcher

基本情報

Profile and Settings

  • 顔写真

  • 氏名

    Okumo Takayuki

  • eメール

    tokumomed.showa-u.ac.jp

Identifiers

  • 研究者番号

    40845773

  • ORCID ID

    0000-0003-4633-6506

  • J-Global ID

    201901005597672656

Affiliation

  • Physiology, Senior Lecturer

Location

  • Hatanodai Campus

Degree

  • Doctor of Medical Science, Showa University, Mar. 2019

Achievements

Published Papers

  • Mechanoreceptor Piezo1 channel-mediated interleukin expression in conjunctival epithelial cells: Linking mechanical stress to ocular inflammation, Fukuoka S, Adachi N, Ouchi E, Ikemoto H, Okumo T, Ishikawa F, Onda H, Sunagawa M., The Ocular Surface, Apr. 2025, Peer-reviewed, DOI:10.1016/j.jtos.2025.01.001
  • Early Intervention With Boiogito to Suppress Knee Osteoarthritis Progression: An Experimental Approach Using a Medial Meniscus Instability Rat Model., Izukashi Kanako;Okumo Takayuki;Tatsuo Tokito;Kachi Itaru;Iida Yuta;Nishio Takumi;Ikemoto Hideshi;Adachi Naoki;Kanzaki Koji;Sunagawa Masataka, Cureus, 17(1), Jan. 2025, Peer-reviewed, DOI:10.7759/cureus.77311
  • Electroacupuncture Inhibits Cartilage Degeneration in a Rat Knee Osteoarthritis (KOA) Model by Suppressing ADAMTS5 Expression, Oyunchimeg Chuluunbat, Hideshi Ikemoto, Takayuki Okumo, Naoki Adachi, Tadashi Hisamitsu, Masataka Sunagawa, Cureus, Nov. 2024, Peer-reviewed
  • Suppressive Activity of Boiogito, a Japanese Traditional Kampo Medicine, on Periostin Secretion in Human Fibroblast-Like Synoviocytes In Vitro., Mochizuki Midori;Okumo Takayuki;Takemura Haruka;Izukashi Kanako;Tatsuo Tokito;Ikemoto Hideshi;Adachi Naoki;Kawate Nobuyuki;Sunagawa Masataka, Cureus, 16(4), Apr. 2024, Peer-reviewed, DOI:https://doi.org/10.7759/cureus.57690
  • The Preventive Effects of Platelet-Rich Plasma Against Knee Osteoarthritis Progression in Rats., Takemura Haruka;Okumo Takayuki;Tatsuo Tokito;Izukashi Kanako;Ikemoto Hideshi;Adachi Naoki;Mochizuki Midori;Kanzaki Koji;Sunagawa Masataka, Cureus, 15(11), Nov. 2023, Peer-reviewed, DOI:https://doi.org/10.7759/cureus.48825
  • Multifactorial Comparative Analysis of Platelet-Rich Plasma and Serum Prepared Using a Commercially Available Centrifugation Kit., Okumo Takayuki;Sato Atsushi;Izukashi Kanako;Ohta Masataka;Oike Jun;Yagura Saki;Okuma Naoki;Koya Takayuki;Sunagawa Masataka;Kanzaki Koji, Cureus, 15(11), Nov. 2023, Peer-reviewed, DOI:https://doi.org/10.7759/cureus.48918
  • Boiogito, a Japanese Traditional Herbal Medicine, Inhibits the Osteoclast Differentiation and Proliferation in the Subchondral Bone of an In Vivo Knee Osteoarthritis Rat Model, Taro Kimura; TAKAYUKI OKUMO; Hideshi Ikemoto; Naoki Adachi; Haruka Takemura; Midori Mochizuki; Kanako Izukashi; Koji Kanzaki; MASATAKA SUNAGAWA, Applied Sciences, 12(22):11518, Nov. 2022, Peer-reviewed, DOI:doi.org/10.3390/app122211518
  • Senso-Immunologic Prospects for Complex Regional Pain Syndrome Treatment., Okumo Takayuki;Takayama Yasunori;Maruyama Kenta;Kato Mami;Sunagawa Masataka, Frontiers in immunology, 12(786511), Jan. 2022, Peer-reviewed, DOI:10.3389/fimmu.2021.786511
  • Analgesic Effect of Boiogito, a Japanese Traditional Kampo Medicine, on Post-Traumatic Knee Osteoarthritis through Inhibition of ERK1/2 Phosphorylation in the Dorsal Horn of the Spinal Cord, Yusuke Kunieda; Takayuki Okumo; Hideshi Ikemoto; Naoki Adachi; Midori Tanaka; Taro Kimura; Kanako Yusa; Koji Kanzaki; Masataka Sunagawa, Applied Sciences, 11(18):8421 - 8421, Sep. 2021, Peer-reviewed
  • Inhibition of Angiogenic Factor Productions by Quercetin In Vitro and In Vivo, Takayuki Okumo; Atsuko Furuta; Tarou Kimura; Kanako Yusa; Kazuhito Asano; Masataka Sunagawa, Medicines, 8(5):22, May 2021, Peer-reviewed, DOI:10.3390/medicines8050022
  • Preventive Effect of the Japanese Traditional Herbal Medicine Boiogito on Posttraumatic Osteoarthritis in Rats, Jun Oike; Takayuki Okumo; Hideshi Ikemoto; Yusuke Kunieda; Shingo Nakai; Haruka Takemura; Hiroshi Takagi; Koji Kanzaki; Masataka Sunagawa, Medicines, 7(12):74, Dec. 2020, Peer-reviewed, DOI:10.3390/medicines7120074
  • Suppressive Activity of Hyaluronic Acid on Adiponectin Production from Mouse Adipocytes In vitro, OKUMO Takayuki;OHASHI Yusuke;TANAKA Midori;ASANO Kazuhito;SUNAGAWA Masataka, International Journal of Pharmaceutical Sciences Research, 7(136), Apr. 2020, Peer-reviewed
  • Suppressive Activity of Fragrance Components on the Development of Allergic Rhinitis Induced by Toluene Diisocyanate Inhalation in Rats, OTAKI Amane; TAKAHASHI Kimiko; OKUMO Takayuki; KITANO Manabu; SUNAGAWA Masataka; ASANO Kazuhito, Japanese Pharmacology & Therapeutics, 47(12):1975 - 1983, Dec. 2019, Peer-reviewed
  • Suppressive Activity of Chondroitin Sulfate on Nitric Oxide (NO) Production by Synoviocytes from Knee Osteoarthritis In Vitro, OKUMO Takayuki;FURUKAWA Suguru;ASANO Kazuhito;KOBAYASHI Hitome;SUNAGAWA Masataka, Int J Pharma Sci Res, 4(125), Nov. 2017, Peer-reviewed

Presentations

  • Early Administration of Boiogito Suppresses Progression of Secondary Osteoarthritis of the Knee in a Rat Model. , Takayuki Okumo, Masataka Sunagawa, Tadashi Hisamitsu, Shogo Ishino, 第75回日本東洋医学会学術総会, 07 Jun. 2025
  • Early Intervention with Boiogito to Suppress Knee Osteoarthritis Progression: An Experimental Approach Using a Medial Meniscus Instability Rat Model, Takayuki Okumo, Kanako Izukashi, Tokito Tatsuo, Hideshi Ikemoto, Naoki Adachi, Masataka Sunagawa, APPW2025, 17 Mar. 2025, 千葉・幕張メッセ
  • Effects of electroacupuncture on joint pain and cartilage degeneration in knee osteoarthritis rats, Hideshi Ikemoto, Chuluunbat Oyunchimeg, Takayuki Okumo, Naoki Adachi, Tadashi Hisamitsu, Masataka Sunagawa, IASP 2024 World Congress on Pain, 06 Aug. 2024, Amsterdam (Netherlands)
  • ヒト滑膜細胞に対する防已黄耆湯のペリオスチン産生抑制効果, 奥茂 敬恭;望月 碧;嚴樫 香名子;辰尾 秋斗;竹村 遥;池本 英志;安達 直樹;川手 信行;砂川 正隆, 第52回日本関節病学会, 19 Jul. 2024, 日本関節病学会, 東京
  • Lowered Patella and Higher Age” the Relevant Predictors of Patellofemoral Osteoarthritis after Anterior Cruciate Ligament Reconstruction of the Knee, Takayuki Okumo, Atsushi Sato, Masataka Ota, Kanako Izukashi, Jun Oike, Saki Yagura, Naoki Okuma, Takayuki Koya, Fumiyoshi Kawashima, Hiroshi Takagi, Koji Kanzaki, ISAKOS Congress 2023, 18 Jun. 2023, Boston, MA, USA
  • Comparison of TGF-b Concentrations between Platelet-rich Plasma and Serum, Takayuki Okumo, Atsushi Sato, Haruka Takemura, Hideshi Ikemoto, Yasunori Takayama, Naoki Adachi, Koji Kanzaki, Masataka Sunagawa, The 100th Anniversary Annual Meeting of The Physiological Society of Japan, 15 Mar. 2023, Kyoto, Japan
  • Suppressive Effect of Boiogito on MMP-13 Production by Fibroblast-like Synoviocyte from Knee Osteoarthritis In Vitro, Takayuki Okumo1,2, Midori Mochizuki1, Hideshi Ikemoto1, Naoki Adachi1, Taro Kimura1,2, Yasunori Takayama1, Mana Tsukada1, Masataka Sunagawa1, The 99th Annual Meeting of the Physiological Society of Japan, 16 Mar. 2022, Sendai, Japan
  • 漢方処方による鎮痛作用の検討～ラット急性炎症性疼痛モデルを用いた基礎研究～, 砂川　正隆;加藤　真未;髙山　靖規;池本　英志;安達　直樹;大橋　祐介;奥茂　敬恭;山口　孝二郎;塚田　愛;石野　尚吾, 第33回日本疼痛漢方研究会学術集会, 03 Jul. 2021, 東京+Web開催
  • Preventive Effect of Boiogito, a Kampo medicine, on Surgically Induced Osteoarthritis in Rats, Takayuki Okumo, Hideshi Ikemoto, Jun Oike, Yusuke Kunieda, Masataka Sunagawa, 第126回日本解剖学会総会･全国学術集会・第98回日本生理学会大会, 28 Mar. 2021, Web開催
  • Suppressive Activity of Chondroitin Sulfate on Nitric Oxide Production by Knee Synoviocytes in Vitro, OKUMO Takayuki;ASANO Kazuhito;IKEMOTO Hideshi;TSUKADA Mana;GUO Shi-yu;KANZAKI Shunji;HISAMITSU Tadashi;SUNAGAWA Masataka, the 9th Federation of the Asian and Oceanian Physiological Societies Congress, 28 Mar. 2019, Kobe

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