Nakatani Yoshihito

Researcher

基本情報

Profile and Settings

• 氏名

  Nakatani Yoshihito

Affiliation

• Health Chemistry, Visiting Professor

Location

• Hatanodai Campus

Degree

• Doctor of Pharmaceutical Science, The University of Tokyo, Mar. 2000

Achievements

Published Papers

• Coordinated action of microsomal prostaglandin E synthase-1 and prostacyclin synthase on contact hypersensitivity., OCHIAI Tsubasa;SASAKI Yuka;KUWATA Hiroshi;NAKATANI Yoshihito;YOKOYAMA Chieko;HARA Shuntaro, Biochem Biophys Res Commun, 546:124 - 129, Mar. 2021, Peer-reviewed
• Gene deletion of microsomal prostaglandin E synthase-1 suppresses chemically induced skin carcinogenesis., SASAKI Yuka;KUWATA Hiroshi;AIDA Eri;OCHIAI Tsubasa;KAMEI Daisuke;NAKATANI Yoshihito;HARA Shuntaro, Anticancer Res, 41(3):1307 - 1314, Mar. 2021, Peer-reviewed
• Involvement of prostacyclin synthase in high-fat-diet-induced obesity., SASAKI Yuka;KUWATA Hiroshi;AKATSU Moe;YAMAKAWA Yuri;OCHIAI Tsubasa;YODA Emiko;NAKATANI Yoshihito;YOKOYAMA Chieko;HARA Shuntaro, Prostaglandins Other Lipid Mediat, 153:106523, Dec. 2020, Peer-reviewed
• Gene Deletion of Calcium-Independent Phospholipase A₂γ (iPLA₂γ) Suppresses Adipogenic Differentiation of Mouse Embryonic Fibroblasts., YODA Emiko;HACHISU Keiko;KUWATA Hiroshi;NAKATANI Yoshihito;HARA Shuntaro, Biol Pharm Bull, 43(9):1375 - 1381, Sep. 2020, Peer-reviewed
• Long-chain acyl-CoA synthetase 4 participates in the formation of highly unsaturated fatty acid-containing phospholipids in murine macrophages., Kuwata Hiroshi;Nakatani Eriko;Shimbara-Matsubayashi Satoko;Ishikawa Fumihiro;Shibanuma Motoko;Sasaki Yuka;Yoda Emiko;Nakatani Yoshihito;Hara Shuntaro, Biochimica et biophysica acta. Molecular and cell biology of lipids, 1864(11):1606 - 1618, Jul. 2019, Peer-reviewed
• Calcium-independent phospholipase A2γ (iPLA2γ) and its roles in cellular functions and diseases., HARA Shuntaro;YODA Emiko;SASAKI Yuka;NAKATANI Yoshihito;KUWATA Hiroshi, Biochim Biophys Acta Mol Cell Biol Lipids, 1864(6):861 - 868, Jun. 2019, Peer-reviewed
• Calcium-independent phospholipase A2γ (iPLA2γ) and its roles in cellular functions and diseases., Hara Shuntaro;Yoda Emiko;Sasaki Yuka;Nakatani Yoshihito;Kuwata Hiroshi, Biochimica et biophysica acta. Molecular and cell biology of lipids, 1864(6), Nov. 2018, Peer-reviewed
• The group VIA calcium-independent phospholipase A2 and NFATc4 pathway mediates IL-1β-induced expression of chemokines CCL2 and CXCL10 in rat fibroblasts., KUWATA Hiroshi;YUZURIHARA Chihiro;KINOSHITA Natsumi;TAKI Yuki;IKEGAMI Yuki;WASHIO Sana;HIRAKAWA Yushi;YODA Emiko;AIUCHI Toshihiro;ITABE Hiroyuki;NAKATANI Yoshihito;HARA Shuntaro, FEBS J, 285(11):2056 - 2070, Jun. 2018, Peer-reviewed
• Cytosolic Prostaglandin E Synthase Is Involved in c-Fos Expression in Rat Fibroblastic 3Y1 cells, NAKATANI Yoshihito;MIYAZAKI Yuki;HARA Shuntaro, Biol Pharm Bull, 40(11):1963 - 1967, Nov. 2017, Peer-reviewed
• Genetic-deletion of Cyclooxygenase-2 Downstream Prostacyclin Synthase Suppresses Inflammatory Reactions but Facilitates Carcinogenesis, unlike Deletion of Microsomal Prostaglandin E Synthase-1, SASAKI Yuka;KAMIYAMA Shuhei;KAMIYAMA Azusa;MATSUMOTO Konomi;AKATSU Moe;NAKATANI Yoshihito;KUWATA Hiroshi;ISHIKAWA Yukio;ISHII Toshiharu;YOKOYAMA Chieko;HARA Shuntaro, Sci Rep, 5(17376):1 - 11, Nov. 2015, Peer-reviewed
• Role of microsomal prostaglandin E synthase-1 (mPGES-1)-derived prostaglandin E2 in colon carcinogenesis, SASAKI Yuka;NAKATANI Yoshihito;HARA Shuntaro, Prostaglandins Other Lipid Mediat, 121:42 - 45, Sep. 2015, Peer-reviewed
• Group VIB calcium-independent phospholipase A2 (iPLA2γ) regulates platelet activation, hemostasis and thrombosis in mice., YODA Emiko; RAI Kohmi; OGAWA Mai; TAKAKURA Yuki; KUWATA Hiroshi; SUZUKI Hidenori; NAKATANI Yoshihito; MURAKAMI Makoto; HARA Shuntaro, PLOS ONE, 9(10):e109409, Oct. 2014, Peer-reviewed
• 10. Group VIB calcium-independent phospholipase A2 (iPLA2γ) regulates platelet activation, hemostasis and thrombosis in mice., YODA Emiko;RAI Kohmi;OGAWA Mai;TAKAKURA Yuki;KUWATA Hiroshi; SUZUKI Hidenori; NAKATANI Yoshihito; MURAKAMI Makoto;HARA Shuntaro, PLOS ONE, e0109409, Oct. 2014, Peer-reviewed, DOI:10.1371/journal.pone.0109409
• Group VIB calcium-independent phospholipase A2 (iPLA2γ) regulates platelet activation, hemostasis and thrombosis in mice., YODA Emiko;RAI Kohmi;OGAWA Mai;TAKAKURA Yuki;KUWATA Hiroshi; SUZUKI Hidenori; NAKATANI Yoshihito; MURAKAMI Makoto;HARA Shuntaro, PLOS ONE, e0109409, Oct. 2014, Peer-reviewed, DOI:10.1371/journal.pone.0109409
• Role of long-chain acyl-coenzyme A synthetases in the regulation of arachidonic acid metabolism in interleukin 1β-stimulated rat fibroblasts., Hiroshi Kuwata; Makiko Yoshimura; Yuka Sasaki; Emiko Yoda; Yoshihito Nakatani; Ichiro Kudo; Shuntaro Hara, Biochimica et biophysica acta, 1841(1):44 - 53, Jan. 2014, Peer-reviewed
• 細胞質型プロスタグランジンE2合成酵素, 中谷　良人, 昭和大学薬学雑誌, 3(1):27 - 34, Jun. 2012, Peer-reviewed
• A novel role of group VIB calcium-independent phospholipase A2 (iPLA2gamma) in the inducible expression of group IIA secretory PLA2 in rat fibroblastic cells., Hiroshi Kuwata; Chikako Fujimoto; Emiko Yoda; Satoko Shimbara; Yoshihito Nakatani; Shuntaro Hara; Makoto Murakami; Ichiro Kudo, The Journal of biological chemistry, 282(28):20124 - 32, Jul. 2007, Peer-reviewed
• Group VIB Ca2+-independent phospholipase A2gamma promotes cellular membrane hydrolysis and prostaglandin production in a manner distinct from other intracellular phospholipases A2., Makoto Murakami; Seiko Masuda; Kaori Ueda-Semmyo; Emiko Yoda; Hiroshi Kuwata; Yasukazu Takanezawa; Junken Aoki; Hiroyuki Arai; Hideki Sumimoto; Yukio Ishikawa; Toshiharu Ishii; Yoshihito Nakatani; Ichiro Kudo, The Journal of biological chemistry, 280(14):14028 - 41, Apr. 2005, Peer-reviewed
• Studies on a mechanism by which cytosolic phospholipase A2 regulates the expression and function of type IIA secretory phospholipase A2, H. Kuwata; S. Yamamoto; Y. Miyazaki; S. Shimbara; Y. Nakatani; H. Suzuki; N. Ueda; S. Yamamoto; M. Murakami; I. Kudo, Journal of Immunology, 165(7):4024 - 4031, Oct. 2000, Peer-reviewed
• Characterization of heparin low-affinity phospholipase A(1) present in brain and testicular tissue, S Uchiyama; Y Miyazaki; Y Amakasu; H Kuwata; Y Nakatani; G Atsumi; M Murakami; Kudo, I, JOURNAL OF BIOCHEMISTRY, 125(6):1001 - 1010, Jun. 1999, Peer-reviewed
• Cytosolic phospholipase A(2) is required for cytokine-induced expression of type IIA secretory phospholipase A(2) that mediates optimal cyclooxygenase-2-dependent delayed prostaglandin E-2 generation in rat 3Y1 fibroblasts, H Kuwata; Y Nakatani; M Murakami; Kudo, I, JOURNAL OF BIOLOGICAL CHEMISTRY, 273(3):1733 - 1740, Jan. 1998, Peer-reviewed
• Cancer cells isolated from malignant pleural and peritoneal effusions inhibit phospholipase A2 activity in human polymorphonuclear leukocytes, Masayoshi Abe; Hisao Kitsuki; Sachiko Saruwatari; Hiroshi Asoh; Tsugutomo Sakurada; Hiroshi Kuwata; Yoshihito Nakatani; Ichiro Kudo; Tatsuo Furukawa, Cancer Letters, 121(2):155 - 161, Dec. 1997, Peer-reviewed
• Prostaglandin E-2 amplifies cytosolic phospholipase A(2)- and cyclooxygenase-2-dependent delayed prostaglandin E-2 generation in mouse osteoblastic cells - Enhancement by secretory phospholipase A(2), M Murakami; H Kuwata; Y Amakasu; S Shimbara; Y Nakatani; G Atsumi; Kudo, I, JOURNAL OF BIOLOGICAL CHEMISTRY, 272(32):19891 - 19897, Aug. 1997, Peer-reviewed
• Phospholipase A(2) inhibitory activity in lung cancer cell lines, M Abe; T Sakurada; H Kuwata; Y Nakatani; Kudo, I; T Furukawa, RECENT ADVANCES IN PROSTAGLANDIN, THROMBOXANE, AND LEUKOTRIENE RESEARCH, 433:343 - 345, 1997

Presentations

• 細胞内ホスホリパーゼA2による細胞遊走因子産生の制御, 桑田　浩;平川　裕士;中谷　良人;原　俊太郎, フォーラム2016　衛生薬学・環境トキシコロジー, 10 Sep. 2016, 東京