Ohta Kiminori

Researcher

基本情報

Profile and Settings

• 氏名

  Ohta Kiminori

Affiliation

• Organic and Medicinal Chemistry, Associate Professor

Location

• Hatanodai Campus

Degree

• Doctor of Pharmaceutical Science, The University of Tokyo, Mar. 2000

Academic Contributions

• Planning etc

Achievements

Published Papers

• Development of Force Field Parameters for p-Carborane to Investigate the Structural Influence of Carborane Derivatives on Drug Targets by Complex Formation, KATO Koichi;NAKAYOSHI Tomoki;INOUE Hiroki;FUKUYOSHI Shuichi;OHTA Kiminori;ENDO Yasuyuki;KURIMOTO Eiji;ODA Akifumi, Biol Pharm Bull, 43(12):1931 - 1939, Dec. 2020, Peer-reviewed
• Antidepressant effect of BE360, a new selective estrogen receptor modulator, activated via CREB/BDNF, Bcl-2 signaling pathways in ovariectomized mice, SAKUMA Wakana;NAKAGAWASAI Osamu;NEMOTO Wataru;ODAIRA Takayo;OGAWA Takumi;OHTA Kiminori;ENDO Yasuyuki;TAN-NO Koichi, Behav Brain Res, 393:112764, Sep. 2020, Peer-reviewed, DOI:10.1016/j.bbr.2020.112764
• Design and Synthesis of Novel Breast Cancer Therapeutic Drug Candidates Based upon the Hydrophobic Feedback Approach of Antiestrogens, OHTA Kiminori;KAISE Asako;TAGUCHI Fumi;AOTO Sayaka;OGAWA Takumi;ENDO Yasuyuki, Molecules, 24(21):3966, Nov. 2019, Peer-reviewed
• ER subtype selectivity of m-carborane-containing phenols: C-alkyl groups on the m-carborane cage enhance ERα selectivity, OHTA Kiminori;OGAWA Takumi;KATO Koichi;ODA Akifumi;Endo Yasuyuki, Bioorg Med Chem Lett, 29(16):2290 - 2293, Aug. 2019, Peer-reviewed
• Anti-​cancer activity of m-​carborane-​containing trimethoxyphenyl derivatives through tubulin polymerization inhibition, KAISE Asako;ENDO Yasuyuki;OHTA Kiminori, Bioorg Med Chem, 27(6):1139 - 1144, Mar. 2019, Peer-reviewed
• An automated microliter-scale high-throughput screening system (MSHTS) for real-time monitoring of protein aggregation using quantum-dot nanoprobes, SASAKI Rina;TAINAKA Reina;ANDO Yuichi;HASHI Yurika;DEEPAK Hadya V;SUGA Yoshiko;MURAI Yuta;ANETAI Masaki;MONDE Kenji;OHTA Kiminori;ITO Ikuko;KIKUCHI Haruhisa;OSHIMA Yoshiteru;ENDO Yasuyuki;NAKAO Hitomi;SAKONO Masafumi;UWAI Koji;TOKURAKU Kiyotaka, Sci Rep, 9(1):2587, Feb. 2019, Peer-reviewed
• Novel androgen receptor full antagonists: Design, synthesis, and a docking study of glycerol and aminoglycerol derivatives that contain p-​carborane cages, KAISE Asako;OHTA Kiminori;FUJII Shinya;ODA Akifumi;GOTO Tokuhito;ENDO Yasuyuki, Bioorg Med Chem, 26(13):3805 - 3811, Jul. 2018, Peer-reviewed

Presentations

• 会員がファルマシアへ期待すること, 太田　公規, 日本薬学会第141年会, 28 Mar. 2021, オンライン開催
• アンドロゲン受容体とカルボラン誘導体との複合体の分子動力学シミュレーション, 金井　涼;加藤　紘一;仲吉　朝希;太田　公規;遠藤　泰之;栗本　英治;小田　彰史, 日本薬学会第140年会, 28 Mar. 2020, Web開催
• 抗腫瘍活性を示すm-カルボラン含有トリメトキシフェニル誘導体, 皆瀨　麻子;太田　公規;遠藤　泰之, 日本薬学会第140年会, 27 Mar. 2020, Ｗeb開催
• キサンチンオキシダーゼ阻害作用を有するトロポロン誘導体の探索, 太田　公規;佐藤　大輔;皆瀨　麻子;遠藤　泰之, 日本薬学会第140年会, 26 Mar. 2020, Web公開
• 新規5-アリールアゾトロポロン誘導体の細胞増殖抑制活性と活性メカニズム, 皆瀬　麻子;氣仙　拓也;畠山　瑞季;太田　公規;佐藤　大輔;今野　茉歩;遠藤　泰之, 日本薬学会第139年会, 21 Mar. 2019, 千葉