MF Researcher Database

Researcher Database

Advance

Shakuo Tomoharu

■FacultyAnesthesiology
■PositionSenior Lecturer
Last Updated :2026/09/02

Researcher

基本情報

Profile and Settings

  • 氏名

    Shakuo Tomoharu

Affiliation

  • Anesthesiology, Senior Lecturer

Location

  • Northern Yokohama Hospital

Degree

  • Doctor of Medical Science, Showa University, Mar. 2016

Achievements

Published Papers

  • Patient- and Operator-Related Factors Associated With Difficult Thoracic Epidural Catheter Placement: A Retrospective Observational Study, Shota Tanimoto • Takuya Mizukami • Ken Hirai • Sae Ono • Tomoharu Shakuo • Yukiko Inoue • Seiji Mochizuki • Takuya Miwa • Masayoshi Kawasaki • Ko Imamura • Atsunori Sakamoto • Megumi Hashimoto • Kenji Shida • Naoki Uchida, Cureus, Aug. 2026, Peer-reviewed, DOI:10.7759/cureus.114927
  • Effective postoperative analgesia using a single-shot intertransverse process block after mastectomy with immediate latissimus dorsi flap reconstruction: A case report, Nobuhide Sasaki; Ken Hirai; Tomoharu Shakuo; Shota Tanimoto; Atsunori Sakamoto; Kenji Shida, JCA Advances, 3(2):100230 - 100230, Jun. 2026, Peer-reviewed, DOI:10.1016/j.jcadva.2026.100230
  • Early Postintubation Hemodynamic Changes Following Remimazolam or Propofol Induction With Simultaneous Bolus Remifentanil in Total Hip Arthroplasty: A Retrospective Observational Study., Sasaki Nobuhide;Shakuo Tomoharu;Morotomi Shinichiro;Tanimoto Shota;Hirai Ken;Ono Sae;Takahashi Kenichi;Dosei Takuya;Ishida Yusuke;Sakamoto Atsunori;Hashimoto Megumi;Shida Kenji, Cureus, 18(6), Jun. 2026, Peer-reviewed, DOI:10.7759/cureus.111755
  • 周術期における全身麻酔下の指輪の取り外しに関する後ろ向き研究, 萩原 有彩 , 橋本 徳 , 道姓 拓也 , 釋尾 知春 , 坂本 篤紀 , 信太 賢治, 臨床麻酔, 50(6):771 - 775, Jun. 2026, Peer-reviewed
  • 緊急帝王切開に至った前置癒着胎盤を合併する妊婦に対する周術期管理, 平井 顕 , 坂本 篤紀 , 川口 由佳 , 釋尾 知春 , 道姓 拓也 , 信太 賢治, 臨床麻酔, 50(6):761 - 766, Jun. 2026, Peer-reviewed
  • Seated Sedation-Analgesia With Preserved Spontaneous Ventilation to Facilitate Intubation After Transition to the Supine Position: A Case Report., Tagawa Ryo;Shakuo Tomoharu;Yamazaki Yutaro;Masunaga Nagisa;Shida Kenji, Cureus, 18(4), Apr. 2026, Peer-reviewed, DOI:10.7759/cureus.106349
  • Effective Use of the Thoracolumbar Interfascial Plane Block With Total IV Anesthesia for Laminoplasty in a Patient With Myasthenia Gravis: A Case Report., Tanimoto Shota;Shakuo Tomoharu;Yamazaki Yutaro;Umetani Yumi;Sakamoto Atsunori;Shida Kenji, Cureus, 18(1), Jan. 2026, Peer-reviewed, DOI:10.7759/cureus.102532
  • 妊婦の側臥位におけるヤコビ線の位置に関する後ろ向き検討, 津島 佑季子;橋本 徳;道姓 拓也;釋尾 知春;山村 彩;坂本 篤紀;信太 賢治, 麻酔, 74(8):521, Aug. 2025, Peer-reviewed, DOI:10.18916/masui.2025080009
  • Anesthesia Management Using Remimazolam in A Patient With Bernard-Soulier Syndrome: A Case Report., Shakuo Tomoharu;Ishida Yusuke;Sugawara Daiki;Ryo Masato;Okazaki Haruko;Oe Katsunori, Clinical case reports, 13(5), May 2025, Peer-reviewed, DOI:10.1002/ccr3.70519
  • How to Achieve Quick Filling of Suprane (desflurane)to D-Vapor, Megumi Hashimoto; Takuya Dousei; Kenichi Takahashi; Tomoharu Shakuo; Atsunori Sakamoto; Kneji Shida, Journal of Clinical Anesthesia (Japan), 49(2):143 - 146, Feb. 2025, Peer-reviewed
  • Bilateral Continuous Thoracic Paravertebral Block for the Pain Management of Multiple Rib Fractures With Flail Chest: A Case Report., Tanimoto Shota;Shakuo Tomoharu;Dosei Takuya;Sakamoto Atsunori;Shida Kenji, Cureus, 16(12), Dec. 2024, Peer-reviewed, DOI:10.7759/cureus.75406
  • Remimazolam Anesthesia for Modified Electroconvulsive Therapy Mitigates Postoperative Agitation., Shimono Shinako;Shakuo Tomoharu;Yamamura Aya;Hashimoto Megumi;Masuda Rikuo;Shida Kenji, Cureus, 16(10), Oct. 2024, Peer-reviewed, DOI:10.7759/cureus.71037
  • 妊婦の褐色細胞腫に対して,腹腔鏡下摘出術を硬膜外併用全身麻酔で施行した1症例, 谷本 翔太;橋本 徳;荘田 博朗;大橋 みどり;釋尾 知春;坂本 篤紀;信太 賢治, 麻酔, 73(8):557, Aug. 2024, Peer-reviewed, DOI:10.18916/masui.2024080009
  • Novel ultrasound-guided lateral approach for modified thoracoabdominal nerve block through the perichondrial approach provides effective analgesia in gynecological lower abdominal surgery, Morotomi Shinichiro; Shakuo Tomoharu; Soda Hiroaki; Tsushima Yukiko; Shida Kenji, The Showa University Journal of Medical Sciences, 36(2):99 - 101, Jun. 2024, Peer-reviewed, DOI:10.15369/sujms.36.99
  • Remimazolam Anesthesia for Thyroid Surgery., Nakagawa Sae;Shakuo Tomoharu;Matsudo Sakurako;Soda Hiroaki;Shida Kenji, Case reports in anesthesiology, 2023, May 2023, Peer-reviewed, DOI:10.1155/2023/2352693
  • クエチアピン長期内服患者の周術期難治性低血圧に対して,長期休薬が有効であった1症例, 谷本 翔太;高橋 健一;釋尾 知春;山村 彩;信太 賢治, 臨床麻酔, 46(11):1401, Nov. 2022, Peer-reviewed
  • 44 Defects in Mitophagy Response in Burns Involved in Poor Regeneration Capacity, Takahiko Tamura; Tomoharu Shakuo; Aki Kahiwagi; Nobuo Yasuda; Wiem Ben Amor; Hiroyuki Morinaga; Mohammed shoeb Khan; Shohei Shinozaki; Masao; Kaneki; Jeevendra Martyn; Shingo Yasuhara, Journal of burn care & research, 41:29 - 30, Mar. 2020, Peer-reviewed, DOI:10.1093/jbcr/iraa024.048
  • 73 Establishment of New Cellular Model Supportive of Burn-Induced Perturbation in Mitophagy Response, Nobuo Yasuda; Tomoharu Shakuo; Aki Kahiwagi; Takahiko Tamura; Masao Kaneki; Mohammed shoeb; Khan Jeevendra Martyn; Shingo Yasuhara, Journal of burn care & research, 40:50 - 50, Mar. 2019, Peer-reviewed, DOI:10.1093/jbcr/irz013.075
  • 77 Microtubule Network Disturbance is Likely the Target of Oxidative-Stress-Induced Mitophagy Perturbation, Nobuo Yasuda; Tomoharu Shakuo; Aki Kahiwagi; Takahiko Tamura; Masao Kaneki Mohammed shoeb; Khan; Jeevendra Martyn; Shingo Yasuhara, Journal of burn care & research, 40:52 - 53, Mar. 2019, Peer-reviewed, DOI:10.1093/jbcr/irz013.079
  • Intraoperative anesthetic management of an infant with a bridging bronchus: A case report, SHAKUO Tomoharu;OE Katsunori;SHIMURA Yuko;AWAKURA Hanae;YAMADA Arata, Paediatr Anaesth, 28(9):815 - 816, Sep. 2018, Peer-reviewed, DOI:10.1111/pan.13451
  • 223 Potential Association of Burn-Induced NMJ Derrangement and Oxidative Stress-Induced AChR Declustering Signal and the Reversal with AChR alpha7 Agonist, Ryusuke Ueki; L Liu; Aki Kahiwagi; Tomoharu Shakuo; Nobuo Yasuda; Munetaka Hirose; Shingo Yasuhara; Jeevendra Martyn, Journal of burn care & research, 39:78 - 78, Apr. 2018, Peer-reviewed, DOI:10.1093/jbcr/iry006.145
  • 225 Pharmacological Ameioration of Perturbed Mitophagy Response (Mitophagy Resistance) in Burns, Ryusuke Ueki; Aki Kahiwagi; Nobuo Yasuda; Tomoharu Shakuo; Mohammed shoeb Khan Y Yu; Munetaka; Hirose; Jeevendra Martyn; Shingo Yasuhara, Journal of burn care & research, 39:80 - 80, Apr. 2018, Peer-reviewed, DOI:10.1093/jbcr/iry006.147
  • Continuous PECS II block for postoperative analgesia in patients undergoing transapical transcatheter aortic valve implantation, SHAKUO Tomoharu;KAKUMOTO Shinichi;KURIBAYASHI Junya;OE Katsunori;SEO Katsuhiro, JA Clin Rep, 3(1):65, Dec. 2017, Peer-reviewed, DOI:10.1186/s40981-017-0135-0
  • Abdominal compartment syndrome during hip arthroscopy for an acetabular fracture: a case report., SHAKUO Tomoharu;BITO Kiyoko;YASUDA Seiichi;ASAGI Chie, JA Clin Rep, 3(1):24, May 2017, Peer-reviewed, DOI:10.1186/s40981-017-0100-y
  • The Effects of Lidocaine on Central Respiratory Neuron Activity and Nociceptive-Related Responses in the Brainstem-Spinal Cord Preparation of the Newborn Rat., SHAKUO Tomoharu;LIN Shih-Tien;ONIMARU Hiroshi, Anesth Analg, 122(5):1586 - 1593, May 2016, Peer-reviewed
  • Effects of ouabain on respiratory rhythm generation in brainstem-spinal cord preparation from newborn rats and in decerebrate and arterially perfused in situ preparation from juvenile rats, TSUZAWA Kayo;YAZAWA Itaru;SHAKUO Tomoharu;IKEDA K;KAWAKAMI K;ONIMARU Hiroshi, Neuroscience, 286:404 - 411, Feb. 2015, Peer-reviewed
  • 小児における術前経口補水液と炭水化物含有飲料の比較　無作為化比較試験, 岩本　泰斗;岩本　梢 ;釋尾　知春;鈴木　尚志 ;世良田　和幸 ;田山　愛;大橋　祐介;鈴木　孝明;渡井　有, 昭和学士会雑誌, 73(6):518 - 525, Dec. 2013, Peer-reviewed, DOI:10.14930/jshowaunivsoc.73.518

Presentations

  • 心臓血管麻酔における 神経ブロックを用いた周術期鎮痛管理 -胸骨正中切開と向き合う-, 釋尾知春, 日本区域麻酔学会第１３回学術集会　シンポジウム・ワークショップ パネル（指名）, 25 Apr. 2026
  • 神経ブロック下肢 TKAの鎮痛がいまいち, 釋尾知春, 神奈川麻酔科医会第５７回学術集会　神経ブロックセミナー講演, 14 Mar. 2026
  • 非心臓手術における TEEの役割, 釋尾知春, 第４３回経食道心エコー講習会, 28 Feb. 2026
  • P172 Experience of using total intravenous anaesthesia with thoracolumbar interfascial plane block in patients with myasthenia gravis undergoing laminoplasty, Shota Tanimoto, Shakuo Tomoharu, Yutaro Yanazaki, Yumi Umetani and Kenji Shida, European Survey Research Association 2025, 10 Sep. 2025
  • 臨床に活かす背部ブロック ～ガイドラインと実践へ向けて～, 釋尾知春, 第７回 ひょうご５国神経ブロック塾, 13 Jun. 2025
  • 臨床で役立つ 超音波の原理, 釋尾知春, 第４１回経食道心エコー講習会, 01 Mar. 2025
  • 修正型電気痙攣療法施行後の興奮対策として,レミマゾラムが有効であった一例, 下野 史菜子, 釋尾 知春, 梅本 理子, 石田 碧, 信太 賢治, 神奈川麻酔科医会第５５回学術集会, 09 Mar. 2024
  • 臨床で役立つ 超音波の原理, 釋尾知春, 第３９回経食道心エコー講習会, 17 Feb. 2024
  • 大動脈弁・僧帽弁再置換術の人工心肺離脱後に生じた低酸素血症に対し一酸化窒素吸入が奏効した1症例, 荘田 博朗, 坂本 篤紀, 釋尾 知春, 高橋 健一, 道姓 拓也, 日本心臓血管麻酔学会第28回学術大会, 16 Sep. 2023
  • レミマゾラムによる全身麻酔下に超重症大動脈弁狭窄症に対する 大動脈弁置換術を施行した1症例, 平木 伶奈、釋尾 知春、坂本 篤紀、髙橋 健一、道姓 拓也、荘田 博朗, 日本心臓血管麻酔学会第２８回学術大会, 16 Sep. 2023
  • レミマゾラムによる全身麻酔下に超重症大動脈弁狭窄症に対する大動脈弁置換術を施行した1症例, 平木 伶奈, 釋尾 知春, 道姓 拓也, 荘田 博朗, 坂本 篤紀, 信太 賢治, 神奈川麻酔科医会第５４回学術集会, 11 Mar. 2023
  • 画像装置の基礎と設定・感染安全管理, 釋尾知春, 第３７回経食道心エコー講習会, 18 Feb. 2023
  • 採卵時の鎮静, 釋尾知春, 第１回FERTILITY CLINIC TOKYO 鎮静セミナー, 21 Jan. 2023
  • 超低出生体重児の動脈管結紮術を分娩室で施行した一例, 高橋 健一, 坂本 篤紀, 釋尾 知春, 荘田 博朗, 道姓 拓也, 日本心臓血管麻酔学会第２７回学術大会, 17 Sep. 2022
  • Eisenmenger化した動脈管開存症患者の仮性動脈瘤手術の麻酔経験, 釋尾 知春, 坂本 篤紀, 高橋 健一, 岩本 泰斗, 荘田 博朗, 道姓 拓也, 日本心臓血管麻酔学会第２７回学術大会, 17 Sep. 2022
  • 微小管保護作用を有するTrehaloseは、酸化ストレスによるmitophagy障害を改善する, 田村 貴彦, 釋尾 知春, 安原 進吾, 第４８回日本集中治療医学会学術集会, 12 Feb. 2021
  • 脳室腹腔シャント留置中の帝王切開に対する脊髄くも膜下麻酔においてdry tapであった麻酔経験, 伊藤 杏奈, 橋本 徳, 大橋 みどり, 荘田 博朗, 釋尾 知春, 山田 新, 信太 賢治, 日本臨床麻酔学会第４０回大会, 06 Nov. 2020
  • Defects in Mitophagy Response in Burns Involved in Poor Regeneration Capacity, Takahiko Tamura, Tomoharu Shakuo, Aki Kahiwagi, Nobuo Yasuda, American Burn Association (Orlando), 17 Mar. 2020
  • Target For Sepsis-induced Disturbed Mitophagy Response Is Likely At The Maturation Process, Jingyuan Chen, Tomoharu Shakuo, Takahiko Tamura, Nobuo Yasuda, American Society of Anesthesiologists Annual Meeting (Orlando), 21 Oct. 2019
  • Mitophagy defect in critical illness deciphered by a novel reporter system with myocytes under oxidative stress, Takahiko Tamura, Nobuo Yasuda, Tomoharu Shakuo, Aki Kashiwagi, American Society of Anesthesiologists Annual Meeting (Orlando), 20 Oct. 2019
  • Essential Roles Of Mitophagy In The Quality Control Of Mitochondrial Functions In Myocytes Exposed To Isoflurane Revealed By Seahorse Analyses, Tomoharu Shakuo, Takahiko Tamura, Masao Kaneki, Shohei Shinozaki, American Society of Anesthesiologists Annual Meeting: Young Investigator Session: finalists (Orlando), 20 Oct. 2019
  • Essential Roles Of Mitophagy In The Quality Control Of Mitochondrial Functions In Myocytes Exposed To Isoflurane Revealed By Seahorse Analyses, Tomoharu Shakuo, Takahiko Tamura, Masao Kaneki, Shohei Shinozaki, American Society of Anesthesiologists Annual Meeting (Orlando), 20 Oct. 2019
  • Essential Roles Of Mitophagy In The Quality Control Of Mitochondrial Functions In Myocytes Exposed To Isoflurane Revealed By Seahorse Analyses, Tomoharu Shakuo, Takahiko Tamura, Masao Kaneki, Shohei Shinozaki, American Society of Anesthesiologists Annual Meeting: Featured Abstracts: finalists (Orlando), 19 Oct. 2019
  • Microtubule Network Disturbance is Likely the Target of Oxidative-Stress-Induced Mitophagy Perturbation, Nobuo Yasuda, Tomoharu Shakuo, Aki Kashiwagi, Takahiko Tamura, American Burn Association (Las Vegas), 02 Apr. 2019
  • Establishment of New Cellular Model Supportive of Burn-Induced Perturbation in Mitophagy Response, Nobuo Yasuda, Tomoharu Shakuo, Aki Kashiwagi, Takahiko Tamura, American Burn Association (Las Vegas), 02 Apr. 2019
  • Novel In Vivo and In Vitro Experimental Models Reveal Isoflurane-induced Mitochondrial Toxicity in Muscular Dystrophy Models, Tomoharu Shakuo, Li Liu, Nobuo Yasuda, Aki Kashiwagi, Hiroshi Otake, American Society of Anesthesiologists Annual Meeting: Young Investigator session: finalists (San Francisco), 14 Oct. 2018
  • Novel In Vivo and In Vitro Experimental Models Reveal Isoflurane-induced Mitochondrial Toxicity in Muscular Dystrophy Models, Tomoharu Shakuo, Nobuo Yasuda, Aki Kashiwagi, Hiroshi Otake, American Society of Anesthesiologists Annual Meeting (San Francisco), 13 Oct. 2018
  • 手術終了直後に体温の急激な上昇を呈し、ダントロレンを使用するに至った乳児の一例, 高橋 健一, 大江 克憲, 道姓 拓也, 粟倉 英恵, 釋尾 知春, 藤井 智子, 志村 裕子, 坂本 篤紀, 日本小児麻酔学会第２４回大会, 08 Oct. 2018
  • Pharmacological Ameioration of Perturbed Mitophagy Response (Mitophagy Resistance) in Burns, Ryusuke Ueki, Aki Kashiwagi, Nobuo Yasuda, Tomoharu Shakuo, American Burn Association (Chicago), 09 Apr. 2018
  • Potential Association of Burn-Induced NMJ Derrangement and Oxidative Stress-Induced AChR Declustering Signal and the Reversal with AChR alpha7 Agonist, Ryusuke Ueki, Li Liu, Aki Kashiwagi, Tomoharu Shakuo, American Burn Association (Chicago), 09 Apr. 2018
  • 気管気管支を合併した乳児に対する術中の気道管理, 釋尾　知春;大江　克憲;粟倉　英恵;髙橋　健一;岩本　泰斗;小坂　誠, 日本小児麻酔学会第21回大会, 29 Aug. 2015, 東京
  • A case of cardiac herniation during left pneumonectomy with pericardiectomy for malignant thymoma, 粟倉　英恵;大江　克憲;吉田　愛;釋尾　知春;志村　裕子;小坂　誠, 日本麻酔科学会関東甲信越・東京支部第54回合同学術集会, 30 Aug. 2014, 東京
  • 食道アカラシアに対するPOEM(Per-Oral Endoscopic Myotomy)の麻酔管理, 行田　梢;橋本　徳;釋尾　知春;岩本　泰斗;藤井　智子;世良田　和幸, 日本麻酔科学会関東甲信越・東京支部第52回合同学術集会, 22 Sep. 2012, 軽井沢町

Books etc

  • Lisa 体幹の神経ブロックがうまくいかない, 心臓手術の末梢神経ブロックがうまくいかない, 谷本翔太，釋尾知春, pp.325-329, (株)メディカル･サイエンス･インターナショナル, Apr. 2026, DOI:https://doi.org/10.11477/mf.134088360330040325
  • 手術のための神経ブロックビジュアル基本手技 : 麻酔科医が知りたいエキスパートの手技, 第2章　脊髄幹ブロック（3. 硬膜外麻酔，4. 仙骨ブロック, 5. 脊髄くま膜下硬膜外併用麻酔, 6. 硬膜穿刺硬膜外麻酔(DEP)）, 釋尾知春, p66-p93, 羊土社, Jul. 2025
  • Lisa 徹底分析シリーズ -誤嚥とご縁にならないために-誤嚥ゼロへの挑戦, 誤嚥の危険因子-誤嚥はあなたのすぐそばに, 釋尾知春, pp. 698-702, (株)メディカル･サイエンス･インターナショナル, Jul. 2025, DOI:https://doi.org/10.11477/mf.134088360320070698

Research Projects

  • 抗血栓療法患者の抜歯時における血液粘弾性分析装置を用いた止血モニタリング法の確立, 増田 陸雄 , 立川 哲史 , 釋尾 知春 , 中澤 碧 , 生方 雄平 , 松村 憲, Coinvestigator, 日本学術振興会 科学研究費助成事業 基盤研究(C), 25K13215, From 20250401, To 20280331
  • Research on Autophagy and Mitophagy in Burn-Induced Skeletal Muscle Dysfunction, 釋尾知春, 公益財団法人 日米医学医療交流財団（JANAMEF） 2017年度 JANAMEF留学助成（A項）, From 20170801, To 20190731

Copyright © MEDIA FUSION Co.,Ltd. All rights reserved.