Murase Remi

Researcher

基本情報

Profile and Settings

• 氏名

  Murase Remi

Affiliation

• Cancer Genome and Pharmacotherapy, Senior Lecturer

Location

• Hatanodai Campus

Degree

• Doctor of Pharmaceutical Science, Showa University, Mar. 2016

Achievements

Published Papers

• Group X phospholipase A2 links colonic lipid homeostasis to systemic metabolism via host-microbiota interaction., Sato Hiroyasu;Taketomi Yoshitaka;Murase Remi;Park Jonguk;Hosomi Koji;Sanada Takayuki Jujo;Mizuguchi Kenji;Arita Makoto;Kunisawa Jun;Murakami Makoto, Cell reports, 43(10):114752, Sep. 2024, Peer-reviewed, DOI:10.1016/j.celrep.2024.114752
• Association of VEGFA and CCL4L2 polymorphisms with hand-foot skin reactions and survival of regorafenib in Japanese patients with colorectal cancer, Koutaro Ono; Remi Murase; Natsumi Matsumoto; Yutaro Kubota; Hiroo Ishida; Ken-ichi Fujita, Cancer Chemotherapy and Pharmacology, 94(1), Mar. 2024, Peer-reviewed
• Association Between ABCC2 -24C>T and Nab-Paclitaxel-induced Peripheral Neuropathy in Japanese Patients With Pancreatic Cancer., Nakayama Hana;Ishida Hiroo;Iidaka Masanori;Kato Shoko;Nakatani Kei;Nakayama Akihiro;Noguchi Toshihiro;Nishihara Shigetoshi;Oikawa Shu;Usami Tomono;Mitsui Yuta;Ishii Y U;Toshima Hirokazu;Kobayashi Kouji;Murase Remi;Matsumoto Natsumi;Suzuki Kosuke;Shimada Ken;Yoshida Hitoshi;Fujita Ken-Ichi, Anticancer research, 44(11), 2024, Peer-reviewed, DOI:https://doi.org/10.21873/anticanres.17326
• A polymorphism in ABCA2 is associated with neutropenia induced by capecitabine in Japanese patients with colorectal cancer., Yukitaka Shibata, Natsumi Matsumoto, Remi Murase, Yutaro Kubota, Hiroo Ishida, Ken Shimada, Ken-ichi Fujita, Cancer Chemother. Pharmacol., 92(6):465 - 474, Dec. 2023, Peer-reviewed, DOI:10.1007/s00280-023-04584-x
• Associations of HLA-C*01:02 and HLA-B*46:01 with regorafenib-induced erythema multiforme in Japanese patients with metastatic colorectal cancer., Fujita Ken-Ichi;Matsumoto Natsumi;Murase Remi;Takeshima Kosuke;Ishida Hiroo;Kubota Yutaro, Clinical and translational science, 16(10):1741 - 1747, Oct. 2023, Peer-reviewed, DOI:10.1111/cts.13589
• Investigation of Hypersensitivity Reactions in Carboplatin Desensitization Therapy., Shibata Naoki;Kawakami Kazuyoshi;Hisanori Shimizu;Kobayashi Kazuo;Yunokawa Mayu;Kanao Hiroyuki;Taki Iori;Murase Remi;Kamei Daisuke;Yamaguchi Masakazu, Anticancer research, 42(2):1091 - 1097, Feb. 2022, Peer-reviewed, DOI:10.21873/anticanres.15571
• Mast Cell-Specific Deletion of Group III Secreted Phospholipase A₂ Impairs Mast Cell Maturation and Functions., TAKETOMI Y;ENDO Y;HIGASHI T;MURASE R;ONO T;TAYA C;KOBAYASHI T;MURAKAMI M, Cells, 10(7):1691, Jul. 2021, Peer-reviewed
• Secreted Phospholipase PLA2G2D Contributes to Metabolic Health by Mobilizing ω3 Polyunsaturated Fatty Acids in WAT., Hiroyasu Sato; Yoshitaka Taketomi; Yoshimi Miki; Remi Murase; Kei Yamamoto; Makoto Murakami, Cell reports, 31(5):107579 - 107579, May 2020, Peer-reviewed
• Effect of intraoral antioxidative capacity in orengedokuto, Hiroaki Nishijima; Satoshi Takamatsu; Kazue Satoh; Remi Murase; Iori Taki; Daisuke Kamei; Kazuyoshi Kawazoe; Yukio Nemoto; Shinichi Iwai, Traditional & Kampo Medicine, 7(1):30 - 37, Apr. 2020, Peer-reviewed
• Five Prognostic Factors for Readmission in Patients Over 75 Years Old with Worsening Heart Failure, SAITO Hiroshi;SHOJI Makoto;TAKI Iori;MURASE Remi;KAMEI Daisuke;SHINKE Toshiro;IWAI Shinichi, The Showa University Journal of Medical Sciences, 32(1):33 - 42, Apr. 2020, Peer-reviewed, DOI:10.15369/sujms.32.33
• Risk of Drug-Induced Accidents and Injuries in Elderly Patients Treated with Specific Drugs Rather than Polypharmacy : Analyses of the Japanese Adverse Drug Event Report Database, HAGA Tomohiro; TAKI-TAKEMOTO Iori; MURASE Remi; KAMEI Daisuke; IWAI Shinichi, The Showa University Journal of Medical Sciences, 31(2):125 - 137, Jun. 2019, Peer-reviewed, DOI:10.15369/sujms.31.125
• Group IID, IIE, IIF and III secreted phospholipase A2s., Makoto Murakami; Yoshimi Miki; Hiroyasu Sato; Remi Murase; Yoshitaka Taketomi; Kei Yamamoto, Biochimica et biophysica acta. Molecular and cell biology of lipids, 1864(6):803 - 818, Jun. 2019, Peer-reviewed
• Anti-inflammatory effects of new catechin derivatives in a hapten-induced mouse contact dermatitis model., Eriko Nakano; Daisuke Kamei; Remi Murase; Iori Taki; Koji Karasawa; Kiyoshi Fukuhara; Shinichi Iwai, European journal of pharmacology, 845:40 - 47, Feb. 2019, Peer-reviewed
• Group III phospholipase A2 promotes colitis and colorectal cancer., Remi Murase; Yoshitaka Taketomi; Yoshimi Miki; Yasumasa Nishito; Moe Saito; Kiyoko Fukami; Kei Yamamoto; Makoto Murakami, Scientific reports, 7(1):12261 - 12261, Sep. 2017, Peer-reviewed
• Secreted phospholipase A2 specificity on natural membrane phospholipids, K. Yamamoto,Y. Miki,H. Sato,R. Murase,Y. Taketomi,M. Murakami, Methods in Enzymology, 583:101 - 117, Nov. 2016, Peer-reviewed
• The roles of the secreted phospholipase A2 gene family in immunology., M. Murakami, K. Yamamoto,Y. Miki, R. Murase,H. Sato,Y. Taketomi, Advances in Immunology, 132:91 - 134, Jun. 2016, Peer-reviewed
• Group X Secreted Phospholipase A2 Releases ω3 Polyunsaturated Fatty Acids, Suppresses Colitis, and Promotes Sperm Fertility., Remi Murase; Hiroyasu Sato; Kei Yamamoto; Ayako Ushida; Yasumasa Nishito; Kazutaka Ikeda; Tetsuyuki Kobayashi; Toshinori Yamamoto; Yoshitaka Taketomi; Makoto Murakami, The Journal of biological chemistry, 291(13):6895 - 6911, Mar. 2016, Peer-reviewed
• Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis., Yoshitaka Taketomi; Noriko Ueno; Takumi Kojima; Hiroyasu Sato; Remi Murase; Kei Yamamoto; Satoshi Tanaka; Mariko Sakanaka; Masanori Nakamura; Yasumasa Nishito; Momoko Kawana; Naotomo Kambe; Kazutaka Ikeda; Ryo Taguchi; Satoshi Nakamizo; Kenji Kabashima; Michael H Gelb; Makoto Arita; Takehiko Yokomizo; Motonao Nakamura; Kikuko Watanabe; Hiroyuki Hirai; Masataka Nakamura; Yoshimichi Okayama; Chisei Ra; Kosuke Aritake; Yoshihiro Urade; Kazushi Morimoto; Yukihiko Sugimoto; Takao Shimizu; Shuh Narumiya; Shuntaro Hara; Makoto Murakami, Nature immunology, 14(6):554 - 63, Jun. 2013, Peer-reviewed

Presentations

• Association of polymorphisms in genes encoding immune response-related factors and regorafenib-induced erythema multiforme in patients with advanced colorectal cancer, Geonwoo Lee, Remi Murase, Natsumi Matsumoto, Yutaro Kubota, Hiroo Ishida and Ken-ichi Fujita, 日本薬学会第145年会, 28 Mar. 2025, 日本薬学会, 福岡
• Examination of inflammation-related polymorphisms involved in regorafenib-induced hand-foot skin reactions., Remi Murase, Natsumi Matsumoto, Yutaro Kubota, Hiroo Ishida, Ken-ichi Fujita, 日本薬学会第145年会, 28 Mar. 2025, 福岡
• Effect of base-line plasma albumin and unbound plasma level of lenvatinib in patients with hepatocellular carcinoma, 鈴木康介、音山裕美、中島陽子、杉浦育也、冨士貴弘、野村英里佳、市川雪、下間祐、打越学、坂木理、水戸守智香、増尾友佑、早野桃花、松本奈都美、村瀬礼美、加藤将夫、吉田仁、藤田健一, 2025 the Japanese Society of Medical Oncology Annual Meeting, 07 Mar. 2025, Japanese Society of Medical Oncology, 神戸コンベンションセンター
• A polymorphism in ABCC3 is associated with capecitabine-induced hand-foot syndrome and capecitabine pharmacokinetics, Kengo Omata, Natsumi Matsumoto, Remi Murase, Yutaro Kubota, Hiroo Ishida3 Ken Shimada, and Ken-ichi Fujita, 2025 the Japanese Society of Medical Oncology Annual Meeting, 06 Mar. 2025
• Association between ABCC2 -24C>T and nab-paclitaxel-induced peripheral neuropathy in Japanese patients with pancreatic cancer, Hana Nakayama,Hiroo Ishida, Masanori Iidaka, Shoko Kato, Kei Nakatani, Akihiro Nakayama, Toshihiro Noguchi, Shigetoshi Nishihara, Shu Oikawa, Tomono Usami, Yuta Mitsui, Yu Ishii, Hirokazu Toshima, Kouji Kobayashi, Remi Murase, Natsumi Matsumoto, Kosuke Suzuki, Ken Shimada, Hitoshi Yoshida, Ken-ichi Fujita, 2025 the Japanese Society Medical Oncology annual Meeting, 06 Mar. 2025, 日本臨床腫瘍学会, 神戸
• Effect of VEGFA and CCL4L2 variants on hand-foot skin reaction and survival of regorafenib in Japanese patients with CRC, Koutaro Ono; Remi Murase; Natsumi Matsumoto; Yutaro Kubota; Hiroo Ishida; Ken-ichi Fujita, 2024 the Japanese Society Medical Oncology Annual Meeting, 22 Feb. 2024, Hirogi Iwata, Nagoya Congress Center
• Associations of polymorphisms in CCL4L1 with regorafenib-induced hand-foot skin reaction in colorectal cancer patients, Koutaro Ono, Remi Murase, Natsumi Matsumoto, Yutaro Kubota, Hiroo Ishida, Takuya Tsunoda, Yasutsuna Sasaki, Ken-ichi Fujita, 2023 the Japanese Society of Medical Oncology Annual Meeting. The 20th Anniversary Meeting, 16 Mar. 2023, Japanese Society of Medical Oncology, Fukuoka International Congress Center/ Marine Messe
• sPLA2-Xは腸内細菌叢の調節を介してメタボリックシンドロームを制御する, 佐藤 弘泰, 武富 芳隆, 村瀬 礼美, 三木 寿美, 原 俊太郎, 細見 晃司, 朴 鐘旭, 水口 賢司, 國澤 純, 村上 誠, 第95回日本生化学会大会, 11 Nov. 2022
• Short-Form McGill Pain Questionnaire 2を用いたプレガバリンの有効性評価, 滝 伊織, 村瀬 礼美, 亀井 大輔, 岩井 信市, 日本薬学会第141年会, 27 Mar. 2021, オンライン開催
• Distinct Roles of Phospholipase A2s in Colitis and Colonic Cancer, MURASE Remi;TAKETOMI Yoshitaka;MIKI Yoshimi;YAMAMOTO Kei;MURAKAMI Makoto, 60th International Conference on the Bioscience of Lipids, 18 Jun. 2019, Tokyo
• インスリングラルギン注のバイオ後続品切り替えに伴う有効性評価, 岡村 駿人, 滝 伊織, 坂田 恵利佳, 村瀬 礼美, 亀井 大輔, 岩井 信市, 第62回日本薬学会関東支部大会, 15 Sep. 2018, 東京
• カテキン誘導体化合物によるアレルギー性接触皮膚炎に対するサイトカイン抑制効果, 中野 恵理子, 亀井 大輔, 村瀬 礼美, 滝 伊織, 唐沢 浩二, 福原 潔, 岩井 信市, 第23回日本フードファクター学会・第12回日本ポリフェノール学会・第15回日本カテキン学会合同学術集会, 07 Sep. 2018, 京都
• Group III phospholipase A2 is a novel promoting factor of colorectal diseases, Remi Murase, Yoshitaka Taketomi, Moe Saito, Yoshimi Miki, Makoto Murakami, 15th International Conference on Bioactive Lipids in Cancer, Inflammation, and Related Diseases, 23 Oct. 2017, Puerto Vallarta, Mexico
• リピドミクスを応用した組織固有のsPLA2依存的脂質代謝経路の探索, 三木寿美, 山本 圭, 佐藤弘泰, 村瀬礼美, 武富芳隆, 村上 誠, 第42回日本医用マススペクトル学会年会, 14 Sep. 2017
• III型分泌性ホスホリパーゼA2は大腸疾患の促進因子である, 村瀬礼美, 武富芳隆, 齋藤萌, 三木寿美, 佐藤弘泰, 深見希代子, 村上誠, 第59回日本脂質生化学会, 15 Jun. 2017
• III型分泌性ホスホリパーゼA2は大腸疾患の新規増悪因子である, 村瀬 礼美, 武富 芳隆, 斎藤 萌, 三木 寿美, 村上 誠, 第89回日本生化学会大会, 26 Sep. 2016
• III型分泌性ホスホリパーゼA2は大腸癌の進展に関わる, 齋藤 萌, 村瀬 礼美, 田中 弘文, 武富 芳隆, 村上 誠, 第88回日本生化学会大会（BMB2015）, 02 Dec. 2015
• ホスホリパーゼA2分子群を起点とした脂質代謝経路による大腸炎の制御, 村瀬 礼美, 武富 芳隆, 佐藤 弘泰, 山本 圭, 山元 俊憲, 村上 誠, 第27回高遠・分子細胞生物学シンポジウム, 26 Aug. 2015, 大津
• Group X sPLA2 mobilizes ω3 polyunsaturated fatty acid metabolites to protect from colitis, MURASE Remi;TAKETOMI Yoshitaka;SATO Hiroyasu;YAMAMOTO Kei;YAMAMOTO Toshinori;MURAKAMI Makoto, 14th International Conference on Bioactive Lipids in Cancer, Inflammation, and Related Diseases, 14 Jul. 2015, Budapest
• Group X sPLA2 protects from colitis by mobilizing ω3 polyunsaturated fatty acid metabolites, MURASE Remi;TAKETOMI Yoshitaka;SATO Hiroyasu;YAMAMOTO Kei;YAMAMOTO Toshinori;MURAKAMI Makoto, The 6th International Conference on Phospholipase A2 and Lipid Mediators (PLM2015), 11 Feb. 2015, 東京
• 炎症性腸疾患における分泌性ホスホリパーゼA2の機能解析, 村瀬 礼美, 武富 芳隆, 佐藤 弘泰, 山本 圭, 山元 俊憲, 村上 誠, 第87回日本生化学会大会, 17 Oct. 2014, 京都

Research Projects

• Elucidation of disease control mechanism through gut microbiota maintenance by extracellular phospholipid-metabolizing enzymes, Remi Murase, 日本学術振興会, 科学研究費, 若手研究, From 20180401, To 20210331